{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T00:14:25Z","timestamp":1709943265600},"reference-count":0,"publisher":"National Institute of Public Health NIH (National Research Institute)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Przegl Epidemiol"],"abstract":"<p><strong>ABSTRACT<\/strong><br \/>We present the case of a young patient who developed pneumonia during the COVID-19 outbreak. The course\u00a0of the disease with involvement of interstitial lung tissue atypical for bacterial infections, the picture of infection\u00a0markers could indicate SARS-CoV-2. The patient was tested by PCR method on admission with negative results.<br \/>Due to the atypical follow-up of the disease, suggesting a severe course of SARS, PCR testing of the material\u00a0collected by BAL was performed BIOFIRE\u00ae FILMARRAY\u00ae Pneumonia plus Panel (bioM\u00e9rieux). <em>Legionella\u00a0pneumophilla<\/em> and coronavirus genetic materials were found. We conclude that in the described case there was\u00a0a bacterial co-infection, paved by virus infection. The similar radiological picture of the two cases of pneumonia,\u00a0as well as the similar infectious response in the blood, specific for atypical infections, may pose a problem in\u00a0the differential diagnosis. The study was able to confirm the bacterial etiology of pneumonia and introduce\u00a0targeted treatment. The patient was discharged from the hospital. We believe that in any case of pneumonia of\u00a0non-bacterial etiology, extending the diagnosis with a PCR pulmonary panel allows early and effective treatment\u00a0of patients. In the treatment of patients with pulmonary interstitial lesions in the course of virus infections, one should always keep in mind the possibility of atypical co-infections.<br \/><br \/><strong>STRESZCZENIE<\/strong><br \/>Przedstawiamy przypadek chorej, u kt\u00f3rej dosz\u0142o do zapalenia p\u0142uc w czasie epidemii COVID-19. Przebieg\u00a0choroby z zaj\u0119ciem tkanki \u015br\u00f3dmi\u0105\u017cszowej p\u0142uc by\u0142 nietypowy dla zaka\u017ce\u0144 bakteryjnych, obraz marker\u00f3w\u00a0zaka\u017cenia m\u00f3g\u0142 wskazywa\u0107 na SARS-CoV-2. Przy przyj\u0119ciu pacjentki wykonano badanie wymazu z tylnej\u00a0\u015bciany gard\u0142a metod\u0105 PCR, uzyskuj\u0105c wynik ujemny. Ze wzgl\u0119du na nietypowy przebieg choroby, sugeruj\u0105cy\u00a0ci\u0119\u017cki przebieg COVID-19, wykonano badanie PCR materia\u0142u pobranego z BAL (Broncho-alveolar lavage -\u00a0P\u0142ukanie p\u0119cherzykowo-oskrzelowe) testem BIOFIRE\u00ae FILMARRAY\u00ae Pneumonia plus Panel (bioM\u00e9rieux).<br \/>Stwierdzono obecno\u015b\u0107 materia\u0142u genetycznego <em>Legionella pneumophilla<\/em> i koronawirusa. Uwa\u017camy, \u017ce w opisanym\u00a0przypadku dosz\u0142o do wsp\u00f3\u0142zaka\u017cenia bakteryjnego utorowanego przez infekcj\u0119 wirusow\u0105. Podobny\u00a0obraz radiologiczny zapalenia p\u0142uc, podobny obraz marker\u00f3w infekcji we krwi, charakterystyczny dla zaka\u017ce\u0144\u00a0atypowych, mo\u017ce stanowi\u0107 problem w diagnostyce r\u00f3\u017cnicowej. W badaniu uda\u0142o si\u0119 potwierdzi\u0107 bakteryjn\u0105\u00a0etiologi\u0119 zapalenia p\u0142uc i wprowadzi\u0107 celowane leczenie. Pacjentka stanie dobrym zosta\u0142a wypisana ze szpitala.<br \/>Uwa\u017camy, \u017ce w ka\u017cdym przypadku ci\u0119\u017ckiego zapalenia p\u0142uc o niejasnej etiologii rozszerzenie diagnostyki\u00a0o panel p\u0142ucny PCR u\u0142atwia wczesne i skuteczne leczenie chorych. W leczeniu pacjent\u00f3w ze zmianami\u00a0\u015br\u00f3dmi\u0105\u017cszowymi p\u0142uc w przebiegu zaka\u017ce\u0144 wirusowych nale\u017cy zawsze pami\u0119ta\u0107 o mo\u017cliwo\u015bci wyst\u0105pienia\u00a0atypowych wsp\u00f3\u0142zaka\u017ce\u0144.<\/p><\/jats:p>","DOI":"10.32394\/pe.77.06","type":"journal-article","created":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T10:24:00Z","timestamp":1686133440000},"page":"59-65","source":"Crossref","is-referenced-by-count":0,"title":["Bacterial complications in patients with coronavirus infection, new diagnostic and therapeutic possibilities"],"prefix":"10.32394","volume":"77","author":[{"given":"M","family":"\u0141ukaszewski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Nelke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17323","published-online":{"date-parts":[[2023,6,7]]},"container-title":["Przeglad Epidemiologiczny"],"original-title":["Powik\u0142ania bakteryjne u pacjent\u00f3w zaka\u017conych koronawirusem, nowe mo\u017cliwo\u015bci diagnostyczne i terapeutyczne"],"link":[{"URL":"https:\/\/www.przeglepidemiol.pzh.gov.pl\/pdf-181110-101671","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.przeglepidemiol.pzh.gov.pl\/pdf-181110-101671","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T08:43:07Z","timestamp":1709887387000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.przeglepidemiol.pzh.gov.pl\/Bacterial-complications-in-patients-with-coronavirus-infection-new-diagnostic-and,181110,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,7]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023]]}},"alternative-id":["181110"],"URL":"https:\/\/doi.org\/10.32394\/pe.77.06","relation":{},"ISSN":["0033-2100","2545-1898"],"issn-type":[{"value":"0033-2100","type":"print"},{"value":"2545-1898","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,7]]}}}