{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T13:04:05Z","timestamp":1784293445336,"version":"3.55.0"},"reference-count":0,"publisher":"National Institute of Public Health NIH (National Research Institute)","issue":"1","license":[{"start":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:00:00Z","timestamp":1783987200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:00:00Z","timestamp":1783987200000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:00:00Z","timestamp":1783987200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rocz Panstw Zakl Hig"],"published-print":{"date-parts":[[2026,7,17]]},"abstract":"<jats:p>The aim of this study was to present the current state of knowledge regarding the use of the ketogenic diet in the treatment\nof obesity in adults, with particular emphasis on its safety, indications, and contraindications, and to relate these findings\nto its established use in drug-resistant epilepsy and other clinical conditions. Despite growing interest in its clinical\napplication, the effectiveness and safety of this intervention remain a matter of debate. A narrative review of the literature\navailable in PubMed and Google Scholar from 2021 to 2024 was conducted using the keywords \u201cketogenic diet,\u201d \u201cobesity,\u201d\n\u201cepilepsy,\u201d \u201ctype 2 diabetes,\u201d \u201ccardiovascular diseases,\u201d \u201cPCOS,\u201d \u201cneurological diseases,\u201d and \u201cpsychiatric disorders,\u201d\nas well as their combinations with AND\/OR operators. Meta-analyses, randomized controlled trials, systematic reviews,\nand selected clinical trials evaluating the effectiveness and safety of the ketogenic diet were included in the analysis. The\nketogenic diet demonstrates effectiveness in short-term weight loss and improvement of selected metabolic parameters in\npatients with obesity. However, its long-term effects remain equivocal and do not appear to offer significant advantages over\nother dietary strategies. The diet is associated with a risk of adverse effects and requires appropriate clinical monitoring.\nWhile it is a recognized and effective therapeutic option for drug-resistant epilepsy, its use in other conditions has not\nbeen established as a standard therapeutic approach. The ketogenic diet may be considered as part of obesity treatment\nin carefully selected patients, provided that potential benefits and risks are individually assessed. Further high-quality\nstudies are needed to determine its long-term effectiveness and safety.<\/jats:p>","DOI":"10.32394\/rpzh\/225527","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T12:12:44Z","timestamp":1784031164000},"page":"33-41","source":"Crossref","is-referenced-by-count":0,"title":["Ketogenic diet in adult obesity: safety, limitations, and evidence from various clinical applications"],"prefix":"10.32394","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-2380-3187","authenticated-orcid":false,"given":"Urszula","family":"Kacprzak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7839-1581","authenticated-orcid":false,"given":"Natalia","family":"Adamaszek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3488-2949","authenticated-orcid":false,"given":"Agnieszka","family":"Buczkowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9484-6634","authenticated-orcid":false,"given":"Julia","family":"Sochowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9936-6975","authenticated-orcid":false,"given":"Michalina","family":"Flejszman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1513-6814","authenticated-orcid":false,"given":"Julia","family":"Danieluk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2270-5027","authenticated-orcid":false,"given":"Justyna","family":"W\u00f3jcik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0795-2992","authenticated-orcid":false,"given":"Laura","family":"Stochaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1422-6940","authenticated-orcid":false,"given":"Micha\u0142","family":"Gli\u0144ski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5448-9956","authenticated-orcid":false,"given":"Dominika","family":"Do\u0142\u0119ga-Mostowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"17323","published-online":{"date-parts":[[2026,7,14]]},"container-title":["Roczniki Pa\u0144stwowego Zak\u0142adu Higieny"],"original-title":[],"link":[{"URL":"https:\/\/roczniki.pzh.gov.pl\/pdf-225527-142416","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/roczniki.pzh.gov.pl\/pdf-225527-142416","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T12:26:25Z","timestamp":1784291185000},"score":1,"resource":{"primary":{"URL":"https:\/\/roczniki.pzh.gov.pl\/Ketogenic-diet-in-adult-obesity-safety-limitations-and-evidence-from-various-clinical,225527,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,14]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"alternative-id":["225527"],"URL":"https:\/\/doi.org\/10.32394\/rpzh\/225527","relation":{},"ISSN":["0035-7715","2451-2311"],"issn-type":[{"value":"0035-7715","type":"print"},{"value":"2451-2311","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,14]]}}}