{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T03:43:53Z","timestamp":1768535033852,"version":"3.49.0"},"reference-count":0,"publisher":"National Institute of Public Health NIH (National Research Institute)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rocz Panstw Zakl Hig"],"abstract":"<jats:p>&lt;p&gt;&lt;strong&gt;ABSTRACT&lt;\/strong&gt;&lt;br \/&gt;&lt;strong&gt;Background.&lt;\/strong&gt; Many scientific reports have shown a decrease in total cerebrovascular disease (CeVD) mortality over the\u00a0past few decades, but too little attention has been paid to premature mortality. CeVD accounted for 22.5% and 17.8% of\u00a0premature cardiovascular disease deaths in Poland, in 2000 and 2016, respectively.&lt;br \/&gt;&lt;strong&gt;Objective.&lt;\/strong&gt; The aim of the study was to analyse premature CeVD mortality in the Polish population in the recent years,\u00a0the dynamics of its changes and the potential factors that may have contributed to the decline in mortality. The main goal\u00a0of the study was to overview the levels and trends in premature CeVD mortality with an emphasis on haemorrhagic,\u00a0ischaemic and unspecified (not specified as haemorrhagic or ischaemic) stroke.&lt;br \/&gt;&lt;strong&gt;Material and methods.&lt;\/strong&gt; The analysis was based on a database of the Central Statistical Office of Poland and included data\u00a0from 2000-2016 on premature cerebrovascular deaths occurring between 25 and 64 years of age (N=104,786). CeVD and\u00a0haemorrhagic, ischaemic or unspecified stroke were coded with ICD-10 codes I60-I69, I61-I62, I63 and I64, respectively.\u00a0&lt;br \/&gt;The analysis included assessment of CeVD deaths distribution and evaluation of age-specific mortality rates in 10-year\u00a0age groups and age-standardised mortality rates (SMR) in the age group 25-64 years, separately for men and women.\u00a0Trends in SMRs have been studied in the period 2000-2016.&lt;br \/&gt;&lt;strong&gt;Results.&lt;\/strong&gt; The number of CeVD deaths decreased by 32.8% in men and 48.8% in women. There was a two-fold decline in\u00a0CeVD mortality: from 59 to 29 male and from 30 to 12 female per 100,000. In addition, a 2-year increase in the median\u00a0age of CeVD death was observed (Men: 56.4 to 58.4 years, Women: 56.4 to 58.7 years, p&lt;0.001). A statistically significant\u00a0decline in mortality (per 100,000) was also noticed for haemorrhagic stroke (Men: 18.7 to 10.4; Women: 9.6 to 3.8),\u00a0ischaemic stroke (Men: 11.8 to 8.4; Women: 4.7 to 3.0) and unspecified stroke (Men: 19.7 to 3.5; Women: 9.1 to 1.3).&lt;br \/&gt;&lt;strong&gt;Conclusions.&lt;\/strong&gt; A substantial decline in premature CeVD mortality was observed in the period 2000-2016. Additionally,\u00a0the number of deaths that could not be classified as haemorrhagic or ischaemic stroke death decreased significantly.&lt;br \/&gt;The increasingly widespread use of new post-stroke therapies and their availability make it possible to expect a further\u00a0decrease in CeVD mortality. However, the necessary actions should be taken to compensate for the disparities in CeVD\u00a0mortality between men and women.&lt;\/p&gt;\n&lt;p&gt;&lt;strong&gt;STRESZCZENIE&lt;\/strong&gt;&lt;br \/&gt;&lt;strong&gt;Wprowadzenie.&lt;\/strong&gt; W wielu doniesieniach naukowych pokazano spadek umieralno\u015bci og\u00f3lnej z powodu chor\u00f3b naczy\u0144\u00a0m\u00f3zgowych (ChNM) w ci\u0105gu ostatnich kilku dekad, ale zbyt ma\u0142o uwagi po\u015bwi\u0119cono przedwczesnej umieralno\u015bci.\u00a0&lt;br \/&gt;ChNM odpowiada\u0142y za 22.5% i 17.8% przedwczesnych zgon\u00f3w z powodu chor\u00f3b uk\u0142adu kr\u0105\u017cenia w Polsce, odpowiednio\u00a0w 2000 i 2016 roku.&lt;br \/&gt;&lt;strong&gt;Cel pracy.&lt;\/strong&gt; Niniejsza praca mia\u0142a na celu analiz\u0119 przedwczesnej umieralno\u015bci z powodu ChNM w populacji polskiej\u00a0w ostatnich latach, dynamik\u0119 jej zmian oraz potencjalne czynniki, kt\u00f3re mog\u0142y przyczyni\u0107 si\u0119 do spadku umieralno\u015bci.&lt;br \/&gt;G\u0142\u00f3wnym celem pracy by\u0142 przegl\u0105d poziom\u00f3w i trend\u00f3w zmian przedwczesnej umieralno\u015bci z powodu ChNM\u00a0ze szczeg\u00f3lnym uwzgl\u0119dnieniem udar\u00f3w krwotocznego, niedokrwiennego i nieokre\u015blonego jako krwotoczny lub\u00a0niedokrwienny.&lt;br \/&gt;&lt;strong&gt;Materia\u0142 i metody.&lt;\/strong&gt; Analiza obejmowa\u0142a dane oficjalnej statystyki pa\u0144stwowej z lat 2000-2016 dotycz\u0105ce przedwczesnych\u00a0zgon\u00f3w z powodu ChNM pojawiaj\u0105cych si\u0119 pomi\u0119dzy 25 a 64 r.\u017c. (N=104,786). Choroby naczy\u0144 m\u00f3zgowych oraz\u00a0udary krwotoczny, niedokrwienny i nieokre\u015blony jako krwotoczny lub niedokrwienny by\u0142y kodowane zgodnie z ICD-10 odpowiednio jako I60-I69, I61-I62, I63 i I64. Analiza obejmowa\u0142a ocen\u0119 rozk\u0142adu liczby zgon\u00f3w spowodowanych\u00a0ChNM, obliczenia wsp\u00f3\u0142czynnik\u00f3w umieralno\u015bci w 10-letnich grupach wieku i standaryzowanych wsp\u00f3\u0142czynnik\u00f3w\u00a0umieralno\u015bci (SMR) w grupie wieku 25-64 lata, osobno dla m\u0119\u017cczyzn i kobiet. Badano te\u017c trendy zmian standaryzowanych\u00a0wsp\u00f3\u0142czynnik\u00f3w umieralno\u015bci w okresie 2000-2016.&lt;br \/&gt;&lt;strong&gt;Wyniki.&lt;\/strong&gt; Liczba zgon\u00f3w z powodu ChNM obni\u017cy\u0142a si\u0119 o 32.8% u m\u0119\u017cczyzn i o 48.8% u kobiet. Zaobserwowano 2-krotne\u00a0zmniejszenie si\u0119 umieralno\u015bci z powodu ChNM: z 59 do 29 m\u0119\u017cczyzn i z 30 do 12 kobiet na 100,000. Dodatkowo\u00a0zaobserwowano wzrost mediany wieku zgonu z powodu ChNM o 2 lata (m\u0119\u017cczy\u017ani: z 56.4 do 58.4 lat, kobiety: z 56.4\u00a0do 58.7 lat, p&lt;0.001). Statystycznie istotny spadek umieralno\u015bci (na 100,000) zosta\u0142 r\u00f3wnie\u017c odnotowany dla udaru\u00a0krwotocznego (m\u0119\u017cczy\u017ani: 18.7 do 10.4; kobiety: 9.6 do 3.8), udaru niedokrwiennego (m\u0119\u017cczy\u017ani: 11.8 do 8.4; kobiety:\u00a04.7 do 3.0) oraz udaru o nieokre\u015blonej jako krwotoczna lub niedokrwienna etiologii (m\u0119\u017cczy\u017ani: 19.7 do 3.5; kobiety: 9.1\u00a0do 1.3).&lt;br \/&gt;&lt;strong&gt;Wnioski.&lt;\/strong&gt; Znacz\u0105cy spadek przedwczesnej umieralno\u015bci z powodu ChNM zosta\u0142 zaobserwowany w okresie 2000-2016.\u00a0Ponadto istotnie zmniejszy\u0142a si\u0119 liczba zgon\u00f3w, kt\u00f3rych nie mo\u017cna sklasyfikowa\u0107 jako spowodowane udarem krwotocznym\u00a0lub niedokrwiennym. Coraz bardziej rozpowszechnione u\u017cycie nowych\u00a0 poudarowych terapii i ich dost\u0119pno\u015b\u0107 pozwalaj\u0105\u00a0si\u0119 spodziewa\u0107 dalszego spadku umieralno\u015bci z powodu ChNM. Jakkolwiek niezb\u0119dne dzia\u0142ania powinny zosta\u0107 podj\u0119te\u00a0w celu wyr\u00f3wnania r\u00f3\u017cnic pomi\u0119dzy przedwczesn\u0105 umieralno\u015bci\u0105 m\u0119\u017cczyzn w stosunku do kobiet.&lt;\/p&gt;<\/jats:p>","DOI":"10.32394\/rpzh.2022.0192","type":"journal-article","created":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T10:53:02Z","timestamp":1648205582000},"page":"87-97","source":"Crossref","is-referenced-by-count":1,"title":["Trends in premature cerebrovascular disease mortality in the Polish population aged 25-64 years, 2000-2016"],"prefix":"10.32394","volume":"73","author":[{"given":"Alicja","family":"Cicha-Miko\u0142ajczyk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra","family":"Piwo\u0144ska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Witold","family":"\u015amigielski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wojciech","family":"Drygas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17323","published-online":{"date-parts":[[2022,3,31]]},"container-title":["Roczniki Pa\u0144stwowego Zak\u0142adu Higieny"],"original-title":[],"link":[{"URL":"https:\/\/roczniki.pzh.gov.pl\/pdf-182703-103199","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/roczniki.pzh.gov.pl\/pdf-182703-103199","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T11:01:29Z","timestamp":1768474889000},"score":1,"resource":{"primary":{"URL":"https:\/\/roczniki.pzh.gov.pl\/Trends-in-premature-cerebrovascular-disease-mortality-in-the-Polish-population-aged,182703,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,31]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022]]}},"alternative-id":["182703"],"URL":"https:\/\/doi.org\/10.32394\/rpzh.2022.0192","relation":{},"ISSN":["0035-7715","2451-2311"],"issn-type":[{"value":"0035-7715","type":"print"},{"value":"2451-2311","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,31]]}}}