{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T22:01:17Z","timestamp":1792101677540,"version":"4.4.0"},"reference-count":0,"publisher":"National Institute of Public Health NIH (National Research Institute)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rocz Panstw Zakl Hig"],"abstract":"<p><strong>ABSTRACT<\/strong><br \/><strong>Background.<\/strong> During the recent years, appropriate attention has been paid to the oxidative stress which damages the\u00a0body\u2019s cells, proteins, and DNA. Therefore, the need of antioxidants becomes a therapeutic and preventive priority. In\u00a0addition, microbial infections also constitute a public health problem.<br \/><strong>Objective.<\/strong> To find efficient, reliable and safe alternatives sources to synthetic antioxidants, antibiotics and antifungals\u00a0drugs.<br \/><strong>Materials and methods.<\/strong> Extract and essential oil of <em>Psidium guajava<\/em> were screened for their antioxidant and\u00a0antimicrobial activities against gram positive bacteria (<em>Enterococcus faecalis<\/em> and <em>Staphylococcus aureus<\/em>), gram negative\u00a0bacteria (<em>Citrobacter freundii, Escherichia coli<\/em> and <em>Pseudomonas sp<\/em>) and fungi (<em>Candida albicans,Candida tropicalis\u00a0<\/em>and <em>Cryptococcus neoformans<\/em>), as well as to determine the functional groups of phytochemicals present in the essential\u00a0oil by Fourier transform infrared spectroscopy (FTIR).<br \/><strong>Results.<\/strong> The results indicate that <em>P. guajava<\/em> leaves extract demonstrated very high antioxidant activity and <em>P.guajava\u00a0<\/em>essential oil showed the highest polyphenols content. The antioxidant capacity showed a significant negative linear\u00a0correlation to total polyphenolic content (TPC) with Pearson\u2019s correlation coefficients. <em>P. guajava<\/em> essential oil shows high\u00a0antibacterial and antifungal activity against all the studied bacteria and fungi. The FTIR analysis of <em>P. guajava<\/em> essential\u00a0oil showed the presence of several functional groups (ethers, esters, ketones, terpenes, alkanes, aldehydes, aromatic\u00a0hydrocarbons, alcohols, and phenols). The relationship between the chemical composition and antimicrobial activity of\u00a0<em>P.guajava<\/em> essential oil suggests that the attribution of its antimicrobial activity to a particular compound or a synergistic\u00a0effects between its different constituents remains difficult.<br \/><strong>Conclusions.<\/strong> The present study demonstrated that <em>Psidium guajava<\/em> is a valuable source of active compounds with antioxidant\u00a0and antimicrobial activities. This finding suggests the new use of the fruits and the leaves extracts of this plant in\u00a0the treatment of bacterial and fungal infections, as well as for the extraction of new antioxidants. Therefore, it is necessary to be carried out in another study to identify the active(s) compound(s) in <em>P.guajava<\/em> essential oil with respect to their\u00a0mechanisms and synergistic actions.<\/p><\/jats:p>","DOI":"10.32394\/rpzh.2022.0199","type":"journal-article","created":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T10:52:56Z","timestamp":1648205576000},"page":"65-77","source":"Crossref","is-referenced-by-count":6,"title":["Chemical composition, antioxidant and antimicrobial activities of Moroccan species of Psidium guajava extracts"],"prefix":"10.32394","volume":"73","author":[{"given":"Youssef","family":"Lahlou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belkassem","family":"El-Amraoui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majida","family":"El-Wahidi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toufiq","family":"Bamhaoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"17323","published-online":{"date-parts":[[2022,3,31]]},"container-title":["Roczniki Pa\u0144stwowego Zak\u0142adu Higieny"],"original-title":[],"link":[{"URL":"https:\/\/roczniki.pzh.gov.pl\/pdf-182701-103197","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/roczniki.pzh.gov.pl\/pdf-182701-103197","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T11:01:28Z","timestamp":1768474888000},"score":1,"resource":{"primary":{"URL":"https:\/\/roczniki.pzh.gov.pl\/Chemical-composition-antioxidant-and-antimicrobial-activities-of-Moroccan-species,182701,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,31]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022]]}},"alternative-id":["182701"],"URL":"https:\/\/doi.org\/10.32394\/rpzh.2022.0199","relation":{},"ISSN":["0035-7715","2451-2311"],"issn-type":[{"value":"0035-7715","type":"print"},{"value":"2451-2311","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,31]]}}}