{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T06:16:29Z","timestamp":1764828989598},"reference-count":0,"publisher":"Negah Scientific Publisher","issue":"0","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BCN"],"abstract":"<jats:p>This study aimed to assess the effect of controlled mouth breathing during the resting-state using functional magnetic resonance imaging (fMRI). Eleven subjects participated in this experiment in which the controlled \u201cNose\u201d and \u201cMouth\u201d breathings of 6 seconds respiratory cycle were performed with a visual cue at 3T MRI. Voxel-wise seed-to-voxel maps and whole-brain region of interest (ROI)-to-ROI connectome maps were analyzed in both \u201cNose&gt;Mouth\u201d and \u201cMouth&gt;Nose\u201d contrasts. As the result, there were more connection pairs in the \u201cMouth\u201d breathing condition, that is, 14 seeds and 14 connecting pairs in the \u201cMouth&gt;Nose\u201d contrast, compared to 7 seeds and 4 connecting pairs in the \u201cNose&gt;Mouth\u201d contrast (false discovery rate (FDR) of P &lt; 0.05). The present study demonstrated that mouth breathing with controlled respiratory cycles could significantly induce alterations in functional connectivity in the resting-state network, suggesting that it can differently affect the resting brain function; in particular, the brain can hardly rest during mouth breathing, as opposed to conventional nasal breathing.<\/jats:p>","DOI":"10.32598\/bcn.2022.2534.1","type":"journal-article","created":{"date-parts":[[2022,6,13]],"date-time":"2022-06-13T10:18:36Z","timestamp":1655115516000},"page":"1-24","source":"Crossref","is-referenced-by-count":1,"title":["Resting-State Functional Connectivity during Controlled Respiratory Cycles using Functional Magnetic Resonance Imaging"],"prefix":"10.32598","volume":"0","author":[{"name":"Biomedical Engineering Research Center, Gachon University, Incheon 21936, Republic of Korea.","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chan-A","family":"Park","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeong-Bae","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Neurology, Gil Medical Center, Gachon University College of Medicine, Incheon 21565, Republic of Korea.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang-Ki","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Radiological Science, College of Health Science, Gachon University, Incheon 21936, Republic of Korea.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17540","published-online":{"date-parts":[[2022,6,13]]},"container-title":["Basic and Clinical Neuroscience Journal"],"original-title":[],"link":[{"URL":"https:\/\/bcn.iums.ac.ir\/article-1-1784-en.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,13]],"date-time":"2022-06-13T10:18:40Z","timestamp":1655115520000},"score":1,"resource":{"primary":{"URL":"https:\/\/bcn.iums.ac.ir\/article-1-1784-en.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,13]]},"references-count":0,"journal-issue":{"issue":"0","published-online":{"date-parts":[[2022,6,13]]}},"URL":"https:\/\/doi.org\/10.32598\/bcn.2022.2534.1","relation":{},"ISSN":["2228-7442","2008-126X"],"issn-type":[{"type":"print","value":"2228-7442"},{"type":"electronic","value":"2008-126X"}],"subject":[],"published":{"date-parts":[[2022,6,13]]}}}