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Rodents are considered the best choice among animal models, because they are characterized by a small size, short induction period, easy diabetes induction, and economic efficiency. This review summarizes data on experimental models of T2DM that are currently used, evaluates their advantages and disadvantages vis-a-vis research, and describes in detail the factors that should be taken into account when using these models. Selection of a suitable model for tackling a particular issue is not always trivial; it affects study results and their interpretation.<\/jats:p>","DOI":"10.32607\/actanaturae.11751","type":"journal-article","created":{"date-parts":[[2022,10,29]],"date-time":"2022-10-29T18:38:12Z","timestamp":1667068692000},"page":"57-68","source":"Crossref","is-referenced-by-count":14,"title":["Type 2 Diabetes Mellitus: Pathogenic Features and Experimental Models in Rodents"],"prefix":"10.32607","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0172-9998","authenticated-orcid":false,"given":"Inessa G.","family":"Gvazava","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. V.","family":"Karimova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. V.","family":"Vasiliev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. 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