{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T13:58:24Z","timestamp":1648562304052},"reference-count":0,"publisher":"Sociedad Chilena de Pediatria","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Chil Pediatr"],"abstract":"<jats:p>Introducci\u00f3n: El hemangioendotelioma hep\u00e1tico (HEH) es un tumor benigno, raro en ni\u00f1os, que se presenta frecuentemente en el primer a\u00f1o de vida. La presentaci\u00f3n cl\u00ednica es variable y su diagn\u00f3stico se realiza en base a la sospecha cl\u00ednica, estudios de laboratorio y de imagen. El objetivo fue describir un caso de hemangioendotelioma hep\u00e1tico multifocal.Caso cl\u00ednico: Ni\u00f1a de 3 meses que present\u00f3 hepatomegalia sin elementos de falla hep\u00e1tica ni cardiaca. Se realiz\u00f3 ecograf\u00eda y tomograf\u00eda de abdomen que orientaron al diagn\u00f3stico de HEH que se confirm\u00f3 con la angioresonancia de abdomen. Recibi\u00f3 glucocorticoides a altas dosis en forma prolongada. Al a\u00f1o y medio de iniciado el tratamiento se evidenci\u00f3 remisi\u00f3n del tumor. Present\u00f3 efectos secundarios por el tratamiento instaurado.Conclusiones: La presencia de una hepatomegalia aislada en un lactante asintom\u00e1tico debe hacer pensar en una probable patolog\u00eda tumoral, orient\u00e1ndonos por la cl\u00ednica e imagenolog\u00eda al diagn\u00f3stico nosol\u00f3gico de la misma. Siempre se debe sospesar las posibles complicaciones con los riesgos de los tratamientos a realizar. En este caso la extensi\u00f3n del tumor y sus probables complicaciones justific\u00f3 el uso de corticoterapia prologada a altas dosis a pesar de sus efectos adversos.<\/jats:p>","DOI":"10.32641\/rchped.v90i3.856","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T18:56:43Z","timestamp":1574276203000},"page":"316","source":"Crossref","is-referenced-by-count":1,"title":["Hemangioendotelioma hep\u00e1tico infantil multifocal"],"prefix":"10.32641","volume":"90","author":[{"given":"Carlos","family":"Zunino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maira","family":"Delgado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo","family":"Giachetto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17639","published-online":{"date-parts":[[2019,6,10]]},"container-title":["Revista Chilena de Pediatr\u00eda"],"original-title":[],"link":[{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/viewFile\/856\/1210","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/viewFile\/856\/1210","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T18:27:51Z","timestamp":1618252071000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/view\/856"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,10]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,6,10]]}},"URL":"https:\/\/doi.org\/10.32641\/rchped.v90i3.856","relation":{},"ISSN":["0370-4106","0370-4106"],"issn-type":[{"value":"0370-4106","type":"electronic"},{"value":"0370-4106","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6,10]]}}}