{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T16:33:55Z","timestamp":1773160435142,"version":"3.50.1"},"reference-count":0,"publisher":"Sociedad Chilena de Pediatria","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Chil Pediatr"],"abstract":"<jats:p>Introducci\u00f3n: S\u00edndrome de Bartter (SB) es una tubulopat\u00eda hereditaria, poco frecuente que tiene dos formas de presentaci\u00f3n, forma grave de inicio antenatal (Bartter neonatal) y forma de aparici\u00f3n m\u00e1s tard\u00eda (Bartter cl\u00e1sico). En su forma antenatal se manifiesta con poliuria fetal, polihidroamnios de inicio precoz y severo, parto prematuro secundario y restricci\u00f3n de crecimiento intrauterino. La etapa postnatal presenta episodios recurrentes de deshidrataci\u00f3n y desbalance electrol\u00edtico que pueden comprometer la sobrevida del paciente.Objetivo: Comunicar un caso de SB neonatal y presentar una revisi\u00f3n de la literatura en esta patolog\u00eda.Caso Cl\u00ednico: Prematuro 35 semanas, con antecedente de severo polihidroamnios diagnosticado a las 27 semanas de gestaci\u00f3n, sin causa aparente. Desde su nacimiento evolucion\u00f3 con poliuria y alcalosis metab\u00f3lica hipokal\u00e9mica haciendo plantear, en primera semana de vida, diagn\u00f3stico de S\u00edndrome de Bartter neonatal. El laboratorio confirm\u00f3 perdidas urinarias de electr\u00f3litos. Fue manejado con balance h\u00eddrico estricto y suplementaci\u00f3n de sodio y potasio, logrando estabilizar peso y desbalance electrol\u00edtico. Se mantiene en control nefrol\u00f3gico, con suplementaci\u00f3n de gluconato de potasio y cloruro de sodio. Se agreg\u00f3 ibuprofeno al cuarto mes como parte del tratamiento. Al s\u00e9ptimo mes de vida, ecograf\u00eda renal demostr\u00f3 nefrocalcinosis. Al a\u00f1o de vida se evidenci\u00f3 hipoacusia sensorioneural profunda requiriendo implante coclear.Conclusi\u00f3n: Presencia de polihidroamnios severo de aparici\u00f3n temprana sin causa identificada debe hacer sospechar SB, que aun siendo infrecuente determina graves alteraciones hidroelectrol\u00edticas y debe ser iniciado su tratamiento precozmente<\/jats:p>","DOI":"10.32641\/rchped.v90i4.932","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T20:09:33Z","timestamp":1574280573000},"page":"437","source":"Crossref","is-referenced-by-count":9,"title":["S\u00edndrome de Bartter: una tubulopat\u00eda infrecuente de inicio antenatal"],"prefix":"10.32641","volume":"90","author":[{"given":"Carmen Luz","family":"G\u00f3mez De la F.","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 M.","family":"Novoa P.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nury","family":"Caviedes R.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17639","published-online":{"date-parts":[[2019,8,14]]},"container-title":["Revista Chilena de Pediatr\u00eda"],"original-title":[],"link":[{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/viewFile\/932\/1126","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/viewFile\/932\/1244","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/viewFile\/932\/1244","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T18:27:56Z","timestamp":1618252076000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/view\/932"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,14]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2019,8,14]]}},"URL":"https:\/\/doi.org\/10.32641\/rchped.v90i4.932","relation":{},"ISSN":["0370-4106","0370-4106"],"issn-type":[{"value":"0370-4106","type":"electronic"},{"value":"0370-4106","type":"print"}],"subject":[],"published":{"date-parts":[[2019,8,14]]}}}