{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T23:10:31Z","timestamp":1789513831859,"version":"build-2803163510"},"reference-count":0,"publisher":"Sociedad Chilena de Pediatria","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Chil Pediatr"],"abstract":"<jats:p>Introducci\u00f3n: Las paniculitis constituyen un grupo de enfermedades que afectan al tejido graso subcut\u00e1neo y se manifiestan cl\u00ednicamente como n\u00f3dulos. Su patogenia no es del todo clara, por lo general es asintom\u00e1tico. El diagn\u00f3stico confirmatorio es histol\u00f3gico.Objetivo: describir las caracter\u00edsticas cl\u00ednicas e histopatol\u00f3gicas de un caso de necrosis grasa, una forma especifica de paniculitis en el reci\u00e9n nacido (RN).Caso Cl\u00ednico: RN femenino de 40 semanas, parto ces\u00e1rea de urgencia por taquicardia fetal m\u00e1s meconio, APGAR 7-8-9. Requiri\u00f3 oxigeno y presi\u00f3n positiva por 5 min. Al quinto d\u00eda de vida present\u00f3 aumento de volumen en tronco posterior, de coloraci\u00f3n eritematosa - viol\u00e1cea, remitente a la palpaci\u00f3n, no doloroso. Ecotomografr\u00eda de piel y partes blandas inform\u00f3 aumento de la ecogenecidad del tejido celular subcut\u00e1neo y p\u00e9rdida de definici\u00f3n de las celdillas adiposas de aproximadamente 42.3 x 9.7 x 20.1 mm, sin presencia de vascularizaci\u00f3n. Biopsia de piel: epidermis con acantosis irregular y ortoqueratosis en cestas; dermis papilar con infiltrado inflamatorio y dermis reticular y tejido adiposo con presencia de infiltrado linfohistocitiario con tendencia a la formaci\u00f3n de n\u00f3dulos, sin compromiso vascular, leves dep\u00f3sitos de colesterol; compatible con necrosis grasa del reci\u00e9n nacido (NGRN). Paciente tuvo regresi\u00f3n completa de la lesi\u00f3n a los tres meses de vida.Conclusiones: se describe un caso compatible cl\u00ednica e histol\u00f3gicamente con NGRN; sin complicaciones durante su observaci\u00f3n. Por lo general esta patolog\u00eda tiene buen pron\u00f3stico, con resoluci\u00f3n espont\u00e1nea, como en nuestro caso.<\/jats:p>","DOI":"10.32641\/rchped.v91i1.1168","type":"journal-article","created":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T02:13:10Z","timestamp":1580955190000},"page":"94","source":"Crossref","is-referenced-by-count":1,"title":["Necrosis grasa del reci\u00e9n nacido"],"prefix":"10.32641","volume":"91","author":[{"given":"Daniel","family":"L\u00f3pez Hurtado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Elias Delgado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Ortega Diaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Sol\u00eds Avaca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heyssel","family":"Carmona Alvarado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Cabello Dur\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"17639","published-online":{"date-parts":[[2020,2,6]]},"container-title":["Revista Chilena de Pediatr\u00eda"],"original-title":[],"link":[{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/viewFile\/1168\/1420","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/viewFile\/1168\/1420","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T18:28:05Z","timestamp":1618252085000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/view\/1168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,6]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,2,6]]}},"URL":"https:\/\/doi.org\/10.32641\/rchped.v91i1.1168","relation":{},"ISSN":["0370-4106","0370-4106"],"issn-type":[{"value":"0370-4106","type":"electronic"},{"value":"0370-4106","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2,6]]}}}