{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T23:19:24Z","timestamp":1771543164378,"version":"3.50.1"},"reference-count":0,"publisher":"Sociedad Chilena de Pediatria","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Chil Pediatr"],"abstract":"<jats:p>Objetivo: describir las terapias utilizadas en lactantes con bronquiolitis aguda admitidos en 20 Unidades de Cuidados Intensivos (UCI) pedi\u00e1tricos miembros de LARed en 5 pa\u00edses latinoamericanos.Pacientes y M\u00e9todo: Estudio observacional retrospectivo, multic\u00e9ntrico, de datos del Registro Latinoamericano de Falla Respiratoria Aguda Pedi\u00e1trica. Se incluyeron ni\u00f1os menores de 2 a\u00f1os ingresados a UCI pedi\u00e1trica por bronquiolitis aguda comunitaria entre mayo-septiembre 2017. Se recolectaron datos demogr\u00e1ficos, cl\u00ednicos, soporte respiratorio, terapias utilizadas y resultados cl\u00ednicos. Se realiz\u00f3 an\u00e1lisis de subgrupos seg\u00fan ubicaci\u00f3n geogr\u00e1fica, tipo financiaci\u00f3n y presencia de academia.Resultados: Ingresaron al registro 1.155 pacientes con falla respiratoria aguda. Seis casos fueron excluidos por no tener formulario completo. De los 1.147 pacientes, 908 eran menores de 2 a\u00f1os. De ellos, 467 tuvieron diagn\u00f3stico de bronquiolitis aguda, correspondiendo a la principal causa de ingreso a UCI pedi\u00e1trica por falla respiratoria aguda (51,4%). Las caracter\u00edsticas demogr\u00e1ficas y de gravedad entre los centros fueron similares. El soporte m\u00e1ximo respiratorio m\u00e1s frecuente fue c\u00e1nula nasal de alto flujo (47%), seguido por ventilaci\u00f3n mec\u00e1nica no invasiva (26%) y ventilaci\u00f3n mec\u00e1nica invasiva (17%), con un coeficiente de variaci\u00f3n (CV) amplio entre los centros. Hubo una gran dispersi\u00f3n en uso de terapias, siendo frecuente el uso de broncodilatadores, antibi\u00f3ticos y corticoides, con CV hasta 400%. El an\u00e1lisis de subgrupos mostr\u00f3 diferencias significativas en soporte respiratorio y tratamientos utilizados. Un paciente falleci\u00f3 en esta cohorte.Conclusi\u00f3n: Detectamos gran variabilidad en el soporte respiratorio y tratamientos entre UCI pedi\u00e1tricas latinoamericanas. Esta variabilidad no es explicada por disparidades demogr\u00e1ficas ni cl\u00ednicas. Esta heterogeneidad de tratamientos deber\u00eda promover iniciativas colaborativas para disminuir la brecha entre la evidencia cient\u00edfica y la pr\u00e1ctica asistencial.<\/jats:p>","DOI":"10.32641\/rchped.v91i2.1156","type":"journal-article","created":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T16:40:47Z","timestamp":1588005647000},"page":"216","source":"Crossref","is-referenced-by-count":8,"title":["Therapeutic variability in infants admitted to Latin-American pediatric intensive units due to acute bronchiolitis"],"prefix":"10.32641","volume":"91","author":[{"given":"Jes\u00fas Alberto","family":"Serra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebasti\u00e1n","family":"Gonz\u00e1lez-Dambrauskas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"V\u00e1squez Hoyos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Crist\u00f3bal","family":"Carvajal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"Donoso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Cruces","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alicia","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Mart\u00ednez Arroyo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Piedad","family":"Sarmiento","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Nu\u00f1ez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Wegner Araya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Camilo","family":"Jaramillo-Bustamante","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"C\u00e9spedes-Lesczinsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Jabornisky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicol\u00e1s","family":"Monteverde-Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara","family":"C\u00f3rdova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4763-074X","authenticated-orcid":false,"given":"Franco","family":"D\u00edaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17639","published-online":{"date-parts":[[2020,4,22]]},"container-title":["Revista Chilena de Pediatr\u00eda"],"original-title":[],"link":[{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/viewFile\/1156\/1947","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/viewFile\/1156\/1947","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T18:28:17Z","timestamp":1618252097000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/view\/1156"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,22]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,4,22]]}},"URL":"https:\/\/doi.org\/10.32641\/rchped.v91i2.1156","relation":{},"ISSN":["0370-4106","0370-4106"],"issn-type":[{"value":"0370-4106","type":"electronic"},{"value":"0370-4106","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4,22]]}}}