{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T10:04:34Z","timestamp":1747217074181,"version":"3.40.5"},"reference-count":0,"publisher":"Sociedad Chilena de Pediatria","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Chil Pediatr"],"abstract":"<jats:p>Introducci\u00f3n: La hemorragia digestiva por hipertensi\u00f3n portal, sin alternativa de tratamiento endosc\u00f3pico o quir\u00fargico por localizaciones ect\u00f3picas, no identificadas del sitio de sangrado o caracter\u00edsticas anat\u00f3micas, constituye un desaf\u00edo terap\u00e9utico en Pediatr\u00eda. El tratamiento habitual incluye la infusi\u00f3n de octre\u00f3tido endovenoso. En los \u00faltimos a\u00f1os, la presentaci\u00f3n de octre\u00f3tido de liberaci\u00f3n prolongada (OCT-LAR) para administraci\u00f3n mensual intramuscular, resulta una alternativa terap\u00e9utica atractiva.Objetivo: Reportar el caso de un lactante con hemorragia digestiva por hipertensi\u00f3n portal que recibi\u00f3 tratamiento exitoso con OCT-LAR.Caso Cl\u00ednico: Paciente de 8 meses de vida, con malformaci\u00f3n de vena porta extrahep\u00e1tica y episodios reiterados de sangrados digestivos con requerimientos transfusionales e infusiones de octr\u00e9otido, sin posibilidad de tratamiento endosc\u00f3pico o quir\u00fargico. Indicamos OCT-LAR intramuscular mensualmente. Despu\u00e9s de diez meses de iniciado el tratamiento, el paciente no repiti\u00f3 sangrados digestivos y no present\u00f3 efectos adversos relacionados a la medicaci\u00f3n.Conclusi\u00f3n: Consideramos que el reporte de este caso puede resultar de utilidad al presentar una nueva alternativa para el tratamiento de pacientes pedi\u00e1tricos con sangrado digestivo por hipertensi\u00f3n portal sin posibilidades terap\u00e9uticas convencionales.<\/jats:p>","DOI":"10.32641\/rchped.v91i2.1184","type":"journal-article","created":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T16:40:47Z","timestamp":1588005647000},"page":"251","source":"Crossref","is-referenced-by-count":0,"title":["Long-acting Release Octreotide for Pediatric Upper Gastrointestinal Bleeding"],"prefix":"10.32641","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8427-5287","authenticated-orcid":false,"given":"I.","family":"Malla","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2994-4502","authenticated-orcid":false,"given":"S.","family":"L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0038-3999","authenticated-orcid":false,"given":"L.","family":"Busquet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2246-5039","authenticated-orcid":false,"given":"J.","family":"Lipsich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2103-5849","authenticated-orcid":false,"given":"S.","family":"Sierre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7565-0196","authenticated-orcid":false,"given":"G.","family":"Cervio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9191-8447","authenticated-orcid":false,"given":"M.","family":"Cuarterolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17639","published-online":{"date-parts":[[2020,4,22]]},"container-title":["Revista Chilena de Pediatr\u00eda"],"original-title":[],"link":[{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/viewFile\/1184\/1422","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/viewFile\/1184\/1427","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/viewFile\/1184\/1427","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T18:28:17Z","timestamp":1618252097000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.revistachilenadepediatria.cl\/index.php\/rchped\/article\/view\/1184"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,22]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,4,22]]}},"URL":"https:\/\/doi.org\/10.32641\/rchped.v91i2.1184","relation":{},"ISSN":["0370-4106","0370-4106"],"issn-type":[{"type":"electronic","value":"0370-4106"},{"type":"print","value":"0370-4106"}],"subject":[],"published":{"date-parts":[[2020,4,22]]}}}