{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T22:06:13Z","timestamp":1648850773883},"reference-count":0,"publisher":"Sociedad Chilena de Pediatria","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Chil Pediatr"],"abstract":"<jats:p>Al menos 50% de los pacientes pedi\u00e1tricos portadores de artritis idiop\u00e1tica juvenil (AIJ) continuar\u00e1 control en reumatolog\u00eda adulto. La clasificaci\u00f3n de la Liga Internacional de Asociaciones de Reumatolog\u00eda (ILAR) vigente, actualmente en revisi\u00f3n, difiere de la clasificaci\u00f3n de las artritis inflamatorias del adulto. Se ha reportado cambios de categor\u00eda en 10,8% de los pacientes durante el seguimiento.Objetivo: Analizar los pacientes con AIJ seguidos al menos 7 a\u00f1os para objetivar cambios de diagn\u00f3stico en la transici\u00f3n, e identificar factores de mal pron\u00f3stico funcional.Pacientes y M\u00e9todo: Estudio retrospectivo en base a registros cl\u00ednicos. Se incluy\u00f3 a la totalidad de los pacientes con AIJ controlados en policl\u00ednico pedi\u00e1trico del Hospital de Puerto Montt entre el a\u00f1o 2005 y 2017, que cumplieron siete o m\u00e1s a\u00f1os de seguimiento. Se realiz\u00f3 an\u00e1lisis descriptivo en base a variables cl\u00ednicas: categor\u00eda diagn\u00f3stica, tiempo de evoluci\u00f3n al diagn\u00f3stico, actividad cl\u00ednica y serol\u00f3gica, y tiempo de evoluci\u00f3n\u00a0al inicio de la terapia farmacol\u00f3gica.Resultados: Se evaluaron 18 pacientes, 3 Oligo-articular (OA) persistente, 1 OA extendida, 4 Poli-articular (PA) factor reumatoide (FR) negativo, 4 PA FR positivo, 5 Sist\u00e9micas, 1 Psori\u00e1tica, todos con seguimiento mayor a 7 a\u00f1os. Once de 18 ni\u00f1os fueron transferidos a adultos. Tres de 11 cambiaron de diagn\u00f3stico a Artritis Reumatoide (AR) m\u00e1s otra enfermedad autoinmune: S\u00edndrome de Sj\u00f6gren + Lupus eritematoso sist\u00e9mico, P\u00farpura trombocitop\u00e9nico inmune, Enfermedad autoinmune no clasificada y cinco de 11 ni\u00f1os de categor\u00eda ILAR: OA a Artritis reumatoide juvenil, OA extendida a PA FR negativo, 3 Sist\u00e9micas a PA FR negativo. Edad de inicio, formas poli-articulares, retrasos en diagn\u00f3stico y comienzo de terapia se asociaron a secuelas e inflamaci\u00f3n persistente.Conclusiones: Ocho de once pacientes transferidos cambiaron denominaci\u00f3n diagn\u00f3stica y\/o presentaron otras enfermedades autoinmunes. Algunos factores de mal pron\u00f3stico deben mejorar.<\/jats:p>","DOI":"10.32641\/rchped.v91i4.1376","type":"journal-article","created":{"date-parts":[[2020,8,14]],"date-time":"2020-08-14T22:45:18Z","timestamp":1597445118000},"source":"Crossref","is-referenced-by-count":0,"title":["Cambio de diagn\u00f3stico y de categor\u00eda diagn\u00f3stica en pacientes con artritis idiop\u00e1tica juvenil"],"prefix":"10.32641","volume":"91","author":[{"given":"Alexis L.","family":"Strickler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Cifuentes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krasna","family":"Mihovilovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fracisca","family":"Vergara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Grez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viviana","family":"Rivera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17639","published-online":{"date-parts":[[2020,8,14]]},"container-title":["Revista Chilena de Pediatr\u00eda"],"original-title":[],"link":[{"URL":"http:\/\/revistachilenadepediatria.cl\/index.php\/rchped\/article\/viewFile\/1376\/2490","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revistachilenadepediatria.cl\/index.php\/rchped\/article\/viewFile\/1376\/2490","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T18:28:40Z","timestamp":1618252120000},"score":1,"resource":{"primary":{"URL":"http:\/\/revistachilenadepediatria.cl\/index.php\/rchped\/article\/view\/1376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,14]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,8,14]]}},"URL":"https:\/\/doi.org\/10.32641\/rchped.v91i4.1376","relation":{},"ISSN":["0370-4106","0370-4106"],"issn-type":[{"value":"0370-4106","type":"electronic"},{"value":"0370-4106","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8,14]]}}}