{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T02:55:03Z","timestamp":1792983303144,"version":"4.5.0"},"reference-count":13,"publisher":"Polish Society of Microbiologists","issue":"3","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Few pieces of research have focused on\n                    <jats:italic>Micrococcus luteus<\/jats:italic>\n                    bloodstream infection (BSI) because of its low incidence; hence data is needed to illustrate this uncommon infection. This study aimed to explore the clinical characteristics of patients with\n                    <jats:italic>M. luteus<\/jats:italic>\n                    BSI. From January 2010 to December 2019, inpatients that met the criteria for\n                    <jats:italic>M. luteus<\/jats:italic>\n                    BSI were included in this study. Data was collected by reviewing electronic records. Ninety-seven patients were enrolled in this study. Sixty-three percent of the patients have a higher neutrophil percentage (NEUT%). The average blood C-reactive protein (CRP) concentration was 5.5 \u00b1 6.4 mg\/dl. 48.5% of the patients had malignancy, and 40.2% underwent invasive surgeries. Linezolid was found to have the largest average diameter of the inhibition zone (36 mm), while erythromycin was found to have the smallest average zone diameter (15 mm). However, some\n                    <jats:italic>M. luteus<\/jats:italic>\n                    strains had a potentially broad antimicrobial resistance spectrum. Cephalosporins (59.2%) and quinolones (21.4%) were the most commonly used antibiotics for empirical therapies. In conclusion,\n                    <jats:italic>M. luteus<\/jats:italic>\n                    BSI mainly happens in immunocompromised patients or those with former invasive surgeries or indwelling catheters.\n                    <jats:italic>M. luteus<\/jats:italic>\n                    strains are less responsive to erythromycin. Cephalosporins and quinolones are effective empirical antibiotics for\n                    <jats:italic>M. luteus<\/jats:italic>\n                    BSI; however, vancomycin and teicoplanin should be considered for potentially broadly drug-resistant\n                    <jats:italic>M. luteus<\/jats:italic>\n                    strains.\n                    <jats:fig id=\"j_pjm-2021-030_fig_001\" position=\"float\" fig-type=\"figure\">\n                      <jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/j_pjm-2021-030_fig_001.jpg\"\/>\n                    <\/jats:fig>\n                  <\/jats:p>","DOI":"10.33073\/pjm-2021-030","type":"journal-article","created":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T06:35:07Z","timestamp":1631169307000},"page":"321-326","source":"Crossref","is-referenced-by-count":69,"title":["Clinical Characteristics of Patients with\n                    <i>Micrococcus luteus<\/i>\n                    Bloodstream Infection in a Chinese Tertiary-Care Hospital"],"prefix":"10.33073","volume":"70","author":[{"given":"MINGHUI","family":"ZHU","sequence":"first","affiliation":[{"name":"Medical School of Chinese People\u2019s Liberation Army , Beijing , China"},{"name":"Department of Respiratory Diseases, First Medical Center of Chinese People\u2019s Liberation Army General Hospital , Beijing , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"QIANG","family":"ZHU","sequence":"additional","affiliation":[{"name":"Department of Respiratory Diseases, First Medical Center of Chinese People\u2019s Liberation Army General Hospital , Beijing , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ZHEN","family":"YANG","sequence":"additional","affiliation":[{"name":"Department of Respiratory Diseases, First Medical Center of Chinese People\u2019s Liberation Army General Hospital , Beijing , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ZHIXIN","family":"LIANG","sequence":"additional","affiliation":[{"name":"Department of Respiratory Diseases, First Medical Center of Chinese People\u2019s Liberation Army General Hospital , Beijing , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18083","published-online":{"date-parts":[[2021,9,17]]},"reference":[{"key":"2026042902453292295_j_pjm-2021-030_ref_001","unstructured":"Andreopoulos T, Papanikolaou G, Politou M, Konstantopoulos K, Stefanou J, Loukopoulos D. Micrococcus luteus: a putative cause of hepatic abscess? Panminerva Med. 2000 Sep;42(3):231\u2013232."},{"key":"2026042902453292295_j_pjm-2021-030_ref_002","unstructured":"CDC. National Healthcare Safety Network (NHSN). Bloodstream infection event (Central line-associated bloodstream infection and non-central line associated bloodstream infection). Atlanta (USA): Centers for Disease Control and Prevention; 2021 [cited 2021 Jun 20]. Available from https:\/\/www.cdc.gov\/nhsn\/pdfs\/pscmanual\/4psc_clabscurrent.pdf"},{"key":"2026042902453292295_j_pjm-2021-030_ref_003","doi-asserted-by":"crossref","unstructured":"Darg\u00e8re S, Cormier H, Verdon R. Contaminants in blood cultures: importance, implications, interpretation and prevention. Clin Microbiol Infect. 2018 Sep;24(9):964\u2013969. https:\/\/doi.org\/10.1016\/j.cmi.2018.03.030","DOI":"10.1016\/j.cmi.2018.03.030"},{"key":"2026042902453292295_j_pjm-2021-030_ref_004","doi-asserted-by":"crossref","unstructured":"Dib JR, Wagenknecht M, Hill RT, Far\u00edas ME, Meinhardt F. First report of linear megaplasmids in the genus Micrococcus. Plasmid. 2010 Jan;63(1):40\u201345. https:\/\/doi.org\/10.1016\/j.plasmid.2009.10.001","DOI":"10.1016\/j.plasmid.2009.10.001"},{"key":"2026042902453292295_j_pjm-2021-030_ref_005","doi-asserted-by":"crossref","unstructured":"Erbasan F. Brain abscess caused by Micrococcus luteus in a patient with systemic lupus erythematosus: case-based review. Rheumatol Int. 2018 Dec;38(12):2323\u20132328. https:\/\/doi.org\/10.1007\/s00296-018-4182-2","DOI":"10.1007\/s00296-018-4182-2"},{"key":"2026042902453292295_j_pjm-2021-030_ref_006","doi-asserted-by":"crossref","unstructured":"Fosse T, Toga B, Peloux Y, Granthil C, Bertrando J, Sethian M. Meningitis due to Micrococcus luteus. Infection. 1985 Nov;13(6): 280\u2013281. https:\/\/doi.org\/10.1007\/BF01645439","DOI":"10.1007\/BF01645439"},{"key":"2026042902453292295_j_pjm-2021-030_ref_007","doi-asserted-by":"crossref","unstructured":"Hirata Y, Sata M, Makiuchi Y, Morikane K, Wada A, Okabe N, Tomoike H. Comparative analysis of Micrococcus luteus isolates from blood cultures of patients with pulmonary hypertension receiving epoprostenol continuous infusion. J Infect Chemother. 2009; 15(6):424\u2013425. https:\/\/doi.org\/10.1007\/s10156-009-0720-X","DOI":"10.1007\/s10156-009-0720-X"},{"key":"2026042902453292295_j_pjm-2021-030_ref_008","doi-asserted-by":"crossref","unstructured":"Ianniello NM, Andrade DC, Ivancic S, Eckardt PA, Lemos Ramirez JC. Native valve infective endocarditis due to Micrococcus luteus in a non-Hodgkin\u2019s lymphoma patient. IDCases. 2019;18: e00657. https:\/\/doi.org\/10.1016\/j.idcr.2019.e00657","DOI":"10.1016\/j.idcr.2019.e00657"},{"key":"2026042902453292295_j_pjm-2021-030_ref_009","doi-asserted-by":"crossref","unstructured":"Khan A, Aung TT, Chaudhuri D. The first case of native mitral valve endocarditis due to Micrococcus luteus and review of the literature. Case Rep Cardiol. 2019 Dec 04;2019:1\u20133. https:\/\/doi.org\/10.1155\/2019\/5907319","DOI":"10.1155\/2019\/5907319"},{"key":"2026042902453292295_j_pjm-2021-030_ref_010","doi-asserted-by":"crossref","unstructured":"Liebl W, Kloos WE, Ludwig W. Plasmid-borne macrolide resistance in Micrococcus luteus. Microbiology. 2002 Aug 01;148(8):2479\u20132487. https:\/\/doi.org\/10.1099\/00221287-148-8-2479","DOI":"10.1099\/00221287-148-8-2479"},{"key":"2026042902453292295_j_pjm-2021-030_ref_011","doi-asserted-by":"crossref","unstructured":"Miltiadous G, Elisaf M. Native valve endocarditis due to Micrococcus luteus: a case report and review of the literature. J Med Case Reports. 2011 Dec;5(1):251. https:\/\/doi.org\/10.1186\/1752-1947-5-251","DOI":"10.1186\/1752-1947-5-251"},{"key":"2026042902453292295_j_pjm-2021-030_ref_012","doi-asserted-by":"crossref","unstructured":"Peces R, Gago E, Tejada F, Laures AS, Alvarez-Grande J. Relapsing bacteraemia due to Micrococcus luteus in a haemodialysis patient with a Perm-Cath catheter. Nephrol Dial Transplant. 1997 Nov 1; 12(11):2428\u20132429. https:\/\/doi.org\/10.1093\/ndt\/12.11.2428","DOI":"10.1093\/ndt\/12.11.2428"},{"key":"2026042902453292295_j_pjm-2021-030_ref_013","unstructured":"Wharton M, Rice JR, McCallum R, Gallis HA. Septic arthritis due to Micrococcus luteus. J Rheumatol. 1986 Jun;13(3):659\u2013660."}],"container-title":["Polish Journal of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/reference-global.com\/pdf\/10.33073\/pjm-2021-030","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:11:19Z","timestamp":1777471879000},"score":1,"resource":{"primary":{"URL":"https:\/\/reference-global.com\/article\/10.33073\/pjm-2021-030"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,1]]},"references-count":13,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,9,17]]},"published-print":{"date-parts":[[2021,9,1]]}},"alternative-id":["10.33073\/pjm-2021-030"],"URL":"https:\/\/doi.org\/10.33073\/pjm-2021-030","relation":{},"ISSN":["2544-4646"],"issn-type":[{"value":"2544-4646","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,1]]}}}