{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T12:49:59Z","timestamp":1782737399442,"version":"3.54.5"},"reference-count":202,"publisher":"National Institute for Health and Care Research","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002001","name":"Health and Social Care Delivery Research (HSDR) Programme","doi-asserted-by":"publisher","award":["NIHR152115"],"award-info":[{"award-number":["NIHR152115"]}],"id":[{"id":"10.13039\/501100002001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journalslibrary.nihr.ac.uk"],"crossmark-restriction":false},"short-container-title":["Health Soc Care Deliv Res"],"abstract":"\n Parts of this abstract have been reproduced with permission from Bradley N, McConnell T, Blair C, O\u2019Halloran P, Prue G, Lynn F,\n et al<\/jats:italic>\n . Integrated palliative care and oncology: a realist synthesis.\n BMC Med<\/jats:italic>\n 2025;\n 23<\/jats:bold>\n :272. https:\/\/doi.org\/10.1186\/s12916-025-04083-1. This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) licence, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: https:\/\/creativecommons.org\/licenses\/by\/4.0\/. The text below includes minor additions and formatting changes to the original text.\n <\/jats:p>\n \n Background<\/jats:title>\n Existing evidence demonstrates the benefits of integrated palliative care for people with cancer and their carers, for improved symptom burden, quality of life and appropriate healthcare resource use. The integration of palliative care and oncology has the potential to improve the quality of life and is recommended by international guidelines. However, it is not yet consistent practice. There are many approaches to integration, but it is unclear what works, for whom and in what contexts to achieve the best possible outcomes for people with cancer, carers and healthcare systems.<\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n \n \n To conduct a realist synthesis to develop a programme theory of how integrated palliative care in cancer works, for whom and in what contexts to achieve improved symptom management and increased quality of life for people with cancer and their carers.<\/jats:p>\n <\/jats:list-item>\n \n To use the programme theory to coproduce, with stakeholders (e.g. patient and public involvement representatives, local, national, international content experts and multidisciplinary practitioners), guidance to inform delivery of best practice and guide future research.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:sec>\n \n Design and methods<\/jats:title>\n Realist review, conducted in accordance with Realist and Meta-narrative Evidence Synthesis: Evolving Standards. Evidence was identified through systematically searching academic databases and through stakeholder engagement. Data were extracted from included articles and were synthesised using a realist logic of analysis to develop explanations of how and why integrated palliative care in oncology works, for whom and in what contexts.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n One hundred and sixty-four papers from 33 countries were included in the review. Integrated palliative care and oncology could improve people with cancer\u2019s outcomes, increase the goal-concordance of care and support workforce well-being. Interventions to support integration should be tailored to the context in which they are delivered. Ensuring the timely delivery of palliative care for people with cancer requires integration that overcomes siloes between oncology, specialist palliative care and primary and community care. The motivation to prioritise the integration of palliative care relies upon all stakeholders first understanding its value. Enriched interdisciplinary collaboration involves developing confidence in their own and their colleagues\u2019 skillsets, facilitating co-ordination between care settings and supporting communication within and between teams. Supportive leadership could promote an institutional culture of acceptance of the value of integrating palliative care into oncology management.<\/jats:p>\n <\/jats:sec>\n \n Limitations<\/jats:title>\n The realist approach to analysis means that findings are based on our interpretation of the data. To manage the high volume of studies, we limited inclusion to documents published since 2010, using qualitative, mixed or economic methods; therefore, we may have excluded relevant documents.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The success of integration is influenced by the ways in which palliative care is understood, prioritised, operationalised and measured within oncology. Through the synthesis of international evidence, this project draws on implementation science to contribute clarity on how integrated palliative care and cancer care can be achieved in practice.<\/jats:p>\n <\/jats:sec>\n \n Future work<\/jats:title>\n Future work should use the implications and recommendations to initiate and optimise palliative care in oncology management.<\/jats:p>\n <\/jats:sec>\n \n Funding<\/jats:title>\n This synopsis presents independent research funded by the National Institute for Health and Care Research (NIHR) Health and Social Care Delivery Research programme as award number NIHR152115.<\/jats:p>\n <\/jats:sec>","DOI":"10.3310\/gjjr3630","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T04:35:07Z","timestamp":1751258107000},"page":"1-100","update-policy":"https:\/\/doi.org\/10.3310\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["A realist synthesis of integrated palliative care and oncology: Synopsis"],"prefix":"10.3310","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5454-5813","authenticated-orcid":true,"given":"Carolyn","family":"Blair","sequence":"first","affiliation":[{"name":"School of Nursing and Midwifery, Queen\u2019s University Belfast, Belfast, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0768-9819","authenticated-orcid":true,"given":"Natasha","family":"Bradley","sequence":"additional","affiliation":[{"name":"School of Nursing and Midwifery, Queen\u2019s University Belfast, Belfast, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0022-7331","authenticated-orcid":true,"given":"Peter","family":"O\u2019Halloran","sequence":"additional","affiliation":[{"name":"School of Nursing and Midwifery, Queen\u2019s University Belfast, Belfast, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2198-3731","authenticated-orcid":true,"given":"Gillian","family":"Prue","sequence":"additional","affiliation":[{"name":"School of Nursing and Midwifery, Queen\u2019s University Belfast, Belfast, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0216-643X","authenticated-orcid":true,"given":"Fiona","family":"Lynn","sequence":"additional","affiliation":[{"name":"School of Nursing and Midwifery, Queen\u2019s University Belfast, Belfast, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1142-6440","authenticated-orcid":true,"given":"Nia","family":"Roberts","sequence":"additional","affiliation":[{"name":"Bodleian Health Care Libraries, University of Oxford, Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5384-4157","authenticated-orcid":true,"given":"Geoff","family":"Wong","sequence":"additional","affiliation":[{"name":"Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5000-8564","authenticated-orcid":true,"given":"Elspeth","family":"Banks","sequence":"additional","affiliation":[{"name":"Living With and Beyond Cancer Research Group, National Cancer Research Institute, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1292-8597","authenticated-orcid":true,"given":"Tracey","family":"McConnell","sequence":"additional","affiliation":[{"name":"School of Nursing and Midwifery, Queen\u2019s University Belfast, Belfast, 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