{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:10:48Z","timestamp":1791472248983,"version":"4.3.4"},"reference-count":170,"publisher":"National Institute for Health and Care Research","issue":"16","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.nationalarchives.gov.uk\/doc\/non-commercial-government-licence\/non-commercial-government-licence.htm"}],"funder":[{"DOI":"10.13039\/501100000664","name":"Health Technology Assessment programme","doi-asserted-by":"publisher","award":["11\/15\/13"],"award-info":[{"award-number":["11\/15\/13"]}],"id":[{"id":"10.13039\/501100000664","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Health Technol Assess"],"abstract":"\n Background<\/jats:title>\n The quality of care for people with dementia in care homes is of concern. Interventions that can improve care outcomes are required.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To investigate the clinical effectiveness and cost-effectiveness of Dementia Care Mapping\u2122 (DCM) for reducing agitation and improving care outcomes for people living with dementia in care homes, versus usual care.<\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n A pragmatic, cluster randomised controlled trial with an open-cohort design, follow-up at 6 and 16 months, integrated cost-effectiveness analysis and process evaluation. Clusters were not blinded to allocation. The primary end point was completed by staff proxy and independent assessors.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n Stratified randomisation of 50 care homes to the intervention and control groups on a 3\u2009:\u20092 ratio by type, size, staff exposure to dementia training and recruiting hub.<\/jats:p>\n <\/jats:sec>\n \n Participants<\/jats:title>\n Fifty care homes were randomised (intervention, n<\/jats:italic>\u2009=\u200931; control, n<\/jats:italic>\u2009=\u200919), with 726 residents recruited at baseline and a further 261 recruited after 16 months. Care homes were eligible if they recruited a minimum of 10 residents, were not subject to improvement notices, had not used DCM in the previous 18 months and were not participating in conflicting research. Residents were eligible if they lived there permanently, had a formal diagnosis of dementia or a score of 4+ on the Functional Assessment Staging Test of Alzheimer\u2019s Disease, were proficient in English and were not terminally ill or permanently cared for in bed. All homes were audited on the delivery of dementia and person-centred care awareness training. Those not reaching a minimum standard were provided training ahead of randomisation. Eighteen homes took part in the process evaluation.<\/jats:p>\n <\/jats:sec>\n \n Intervention<\/jats:title>\n Two staff members from each intervention home were trained to use DCM and were asked to carry out three DCM cycles; the first was supported by an external expert.<\/jats:p>\n <\/jats:sec>\n \n Main outcome measures<\/jats:title>\n The primary outcome was agitation (Cohen-Mansfield Agitation Inventory), measured at 16 months. Secondary outcomes included resident behaviours and quality of life.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n There were 675 residents in the final analysis (intervention, n<\/jats:italic>\u2009=\u2009388; control, n<\/jats:italic>\u2009=\u2009287). There was no evidence of a difference in agitation levels between the treatment arms. The adjusted mean difference in Cohen-Mansfield Agitation Inventory score was \u20132.11 points, being lower in the intervention group than in the control (95% confidence interval \u20134.66 to 0.44; p<\/jats:italic>\u2009=\u20090.104; adjusted intracluster correlation coefficient: control\u2009=\u20090, intervention\u2009=\u20090.001). The sensitivity analyses results supported the primary analysis. No differences were detected in any of the secondary outcomes. The health economic analyses indicated that DCM was not cost-effective. Intervention adherence was problematic; only 26% of homes completed more than their first DCM cycle. Impacts, barriers to and facilitators of DCM implementation were identified.<\/jats:p>\n <\/jats:sec>\n \n Limitations<\/jats:title>\n The primary completion of resident outcomes was by staff proxy, owing to self-report difficulties for residents with advanced dementia. Clusters were not blinded to allocation, although supportive analyses suggested that any reporting bias was not clinically important.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n There was no benefit of DCM over control for any outcomes. The implementation of DCM by care home staff was suboptimal compared with the protocol in the majority of homes.<\/jats:p>\n <\/jats:sec>\n \n Future work<\/jats:title>\n Alternative models of DCM implementation should be considered that do not rely solely on leadership by care home staff.<\/jats:p>\n <\/jats:sec>\n \n Trial registration<\/jats:title>\n Current Controlled Trials ISRCTN82288852.<\/jats:p>\n <\/jats:sec>\n \n Funding<\/jats:title>\n This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment<\/jats:italic>; Vol. 24, No. 16. See the NIHR Journals Library website for further project information.<\/jats:p>\n <\/jats:sec>","DOI":"10.3310\/hta24160","type":"journal-article","created":{"date-parts":[[2020,3,27]],"date-time":"2020-03-27T14:51:02Z","timestamp":1585320662000},"page":"1-172","update-policy":"https:\/\/doi.org\/10.3310\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":30,"title":["Dementia Care Mapping\u2122 to reduce agitation in care home residents with dementia: the EPIC cluster RCT"],"prefix":"10.3310","volume":"24","clinical-trial-number":[{"clinical-trial-number":"isrctn82288852","registry":"10.18810\/isrctn","type":"results"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4312-6661","authenticated-orcid":true,"given":"Claire A","family":"Surr","sequence":"first","affiliation":[{"name":"Centre for Dementia Research, School of Health and Community Studies, Leeds Beckett University, Leeds, 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Low Expectations: Attitudes on Choice, Care and Community for People with Dementia in Care Homes. London: Alzheimer\u2019s Society; 2013."},{"key":"key2020032516161965_ref1-bib3","unstructured":"Care Quality Commission. The State of Adult Social Care Services 2014 to 2017. Newcastle upon Tyne: Care Quality Commission; 2017."},{"key":"key2020032516161965_ref1-bib4","unstructured":"All-Party Parliamentary Group on Dementia. Always a Last Resort: Inquiry into the Prescription of Antipsychotic Drugs to People with Dementia Living in Care Homes. London: The Stationery Office; 2008."},{"key":"key2020032516161965_ref1-bib5","unstructured":"Department of Health and Social Care (DHSC). Quality Outcomes for People with Dementia: Building on the Work of the National Dementia Strategy. London: DHSC; 2010."},{"key":"key2020032516161965_ref1-bib6","unstructured":"Department of Health and Social Care (DHSC). Living Well with Dementia: A National Dementia Strategy. London: DHSC; 2009."},{"key":"key2020032516161965_ref1-bib7","unstructured":"Department of Health and Social Care (DHSC). Prime Minister\u2019s Challenge on Dementia: Delivering Major Improvements in Dementia Care and Research by 2015. London: DHSC; 2012."},{"key":"key2020032516161965_ref1-bib8","unstructured":"Department of Health and Social Care (DHSC). Prime Minister\u2019s Challenge on Dementia 2020. London: DHSC; 2015."},{"key":"key2020032516161965_ref1-bib9","unstructured":"Ministerial Advisory Group on Dementia Research. The Ministerial Advisory Group on Dementia Research: Headline Report. London: Department of Health and Social Care; 2011."},{"key":"key2020032516161965_ref1-bib10","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1002\/(SICI)1099-1166(199707)12:7<718::AID-GPS608>3.0.CO;2-3","article-title":"The relationship between patient behaviour and environmental quality for the dementing","volume":"12","author":"Bowie","year":"1997","journal-title":"Int J Geriatr Psychiatry"},{"key":"key2020032516161965_ref1-bib11","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1017\/S1041610201007499","article-title":"Quality of life for people with dementia living in residential and nursing home care: the impact of performance on activities of daily living, behavioral and psychological symptoms, language skills, and psychotropic drugs","volume":"13","author":"Ballard","year":"2001","journal-title":"Int Psychogeriatr"},{"key":"key2020032516161965_ref1-bib12","unstructured":"All-Party Parliamentary Group on Dementia. Prepared to Care. Challenging the Dementia Skills Gap. London: The Stationery Office; 2009."},{"key":"key2020032516161965_ref1-bib13","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1017\/S1041610206004352","article-title":"Nursing home staff training in dementia care: a systematic review of evaluated programs","volume":"19","author":"Kuske","year":"2007","journal-title":"Int Psychogeriatr"},{"key":"key2020032516161965_ref1-bib14","doi-asserted-by":"publisher","first-page":"966","DOI":"10.3102\/0034654317723305","article-title":"Effective dementia education and training for the health and social care workforce: a systematic review of the literature","volume":"87","author":"Surr","year":"2017","journal-title":"Rev Educ Res"},{"key":"key2020032516161965_ref1-bib15","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1002\/gps.4072","article-title":"The disconnect between evidence and practice: a systematic review of person-centred interventions and training manuals for care home staff working with people with dementia","volume":"29","author":"Fossey","year":"2014","journal-title":"Int J Geriatr Psychiatry"},{"key":"key2020032516161965_ref1-bib16","volume-title":"Evaluating Dementia Care. 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Can it be done?","volume":"51","author":"Brooker","year":"1994","journal-title":"PSIGE Newsletter"},{"key":"key2020032516161965_ref1-bib22","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1080\/13607869856957","article-title":"The efficacy of Dementia Care Mapping as an audit tool: report of a 3-year British NHS evaluation","volume":"2","author":"Brooker","year":"1998","journal-title":"Aging Ment Health"},{"key":"key2020032516161965_ref1-bib23","first-page":"10","article-title":"Spreading DCM far and wide in Suffolk","volume":"14","author":"Clare","year":"2006","journal-title":"J Dement Care"},{"key":"key2020032516161965_ref1-bib24","first-page":"12","article-title":"DCM 8 in Cheshire","volume":"14","author":"Edwards","year":"2006","journal-title":"J Dement Care"},{"key":"key2020032516161965_ref1-bib25","first-page":"10","article-title":"Evaluating care services for people living with dementia","volume":"8","author":"Jacques","year":"1996","journal-title":"Elder Care"},{"key":"key2020032516161965_ref1-bib26","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1046\/j.1365-2850.2000.00264.x","article-title":"Anti oppressive practice: a route to the empowerment of people with dementia through communication and choice","volume":"7","author":"Martin","year":"2000","journal-title":"J Psychiatr Ment Health Nurs"},{"key":"key2020032516161965_ref1-bib27","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1046\/j.1351-0126.2001.00427.x","article-title":"Person-centred care for people with dementia: a quality audit approach","volume":"8","author":"Martin","year":"2001","journal-title":"J Psychiatr Ment Health Nurs"},{"key":"key2020032516161965_ref1-bib28","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1002\/gps.930081211","article-title":"Dementia Care Mapping: a pilot study of its implementation in a psychogeriatric service","volume":"8","author":"Wilkinson","year":"1993","journal-title":"Int J Geriatr Psychiatry"},{"key":"key2020032516161965_ref1-bib29","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1046\/j.1365-2648.1997.1997025316.x","article-title":"The use of \u2018dementia care mapping\u2019 as a method of evaluating care received by patients with dementia \u2013 an initiative to improve quality of life","volume":"25","author":"Williams","year":"1997","journal-title":"J Adv Nurs"},{"key":"key2020032516161965_ref1-bib30","doi-asserted-by":"publisher","first-page":"729","DOI":"10.2165\/11319240-000000000-00000","article-title":"Management of neuropsychiatric symptoms in people with dementia","volume":"24","author":"Ballard","year":"2010","journal-title":"CNS Drugs"},{"key":"key2020032516161965_ref1-bib31","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1002\/1099-1166(200101)16:1<39::AID-GPS269>3.0.CO;2-F","article-title":"Prevalence and pharmacological management of behavioural and psychological symptoms amongst dementia sufferers living in care environments","volume":"16","author":"Margallo-Lana","year":"2001","journal-title":"Int J Geriatr Psychiatry"},{"key":"key2020032516161965_ref1-bib32","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1017\/S1041610206004224","article-title":"An individualized psychosocial approach for \u2018treatment resistant\u2019 behavioral symptoms of dementia among aged care residents","volume":"19","author":"Davison","year":"2007","journal-title":"Int Psychogeriatr"},{"key":"key2020032516161965_ref1-bib33","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1136\/jnnp.2005.072983","article-title":"Quality of life in dementia: more than just cognition. 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