{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T02:07:57Z","timestamp":1789092477955,"version":"build-2803163510"},"reference-count":72,"publisher":"National Institute for Health and Care Research","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000664","name":"Health Technology Assessment programme","doi-asserted-by":"publisher","award":["NIHR128128"],"award-info":[{"award-number":["NIHR128128"]}],"id":[{"id":"10.13039\/501100000664","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journalslibrary.nihr.ac.uk"],"crossmark-restriction":false},"short-container-title":["Health Technol Assess"],"abstract":"Background<\/jats:title>\nPeople with severe mental illness who experience co-occurring substance use experience poor outcome including suicide, violence, relapses and use of crisis services. They struggle to access care and treatment due to a lack of an integrated and co-ordinated approach which means that some people can fall between services. Despite these concerns, there is limited evidence as to what works for this population.<\/jats:p>\n<\/jats:sec>\nObjectives<\/jats:title>\nTo undertake a realist evaluation of service models in order to identify and refine programme theories of what works under what contexts for this population.<\/jats:p>\n<\/jats:sec>\nDesign<\/jats:title>\nRealist synthesis and evaluation using published literature and case study data.<\/jats:p>\n<\/jats:sec>\nSetting<\/jats:title>\nMental health, substance use and related services that had some form of service provision in six locations in the United Kingdom (five in England and one in Northern Ireland).<\/jats:p>\n<\/jats:sec>\nParticipants<\/jats:title>\nPeople with lived experience of severe mental illness and co-occurring substance use, carers and staff who work in the specialist roles as well as staff in mental health and substance use services.<\/jats:p>\n<\/jats:sec>\nResults<\/jats:title>\nEleven initial programme theories were generated by the evidence synthesis and in conjunction with stakeholders. These theories were refined through focus groups and interviews with 58 staff, 25 service users and 12 carers across the 6 case study areas. We identified three forms of service provision (network, consultancy and lead and link worker); however, all offered broadly similar interventions. Evidence was identified to support most of the 11 programme theories. Theories clustered around effective leadership, workforce development and collaborative integrated care pathways. Outcomes that are meaningful for service users and staff were identified, including the importance of engagement.<\/jats:p>\n<\/jats:sec>\nLimitations<\/jats:title>\nThe requirement for online data collection (due to the COVID-19 pandemic) worked well for staff data but worked less well for service users and carers. Consequently, this may have reduced the involvement of those without access to information technology equipment.<\/jats:p>\n<\/jats:sec>\nConclusion<\/jats:title>\nThe realist evaluation co-occurring study provides details on how and in what circumstances integrated care can work better for people with co-occurring severe mental health and alcohol\/drug conditions. This requires joined-up policy at government level and local integration of services. We have also identified the value of expert clinicians who can support the workforce in sustaining this programme of work. People with co-occurring severe mental health and alcohol\/drug conditions have complex and multifaceted needs which require a comprehensive and long-term integrated approach. The shift to integrated health and social care is promising but will require local support (local expert leaders, network opportunities and clarity of roles).<\/jats:p>\n<\/jats:sec>\nFuture work<\/jats:title>\nFurther work should evaluate the effectiveness and cost-effectiveness of service models for this group.<\/jats:p>\n<\/jats:sec>\nStudy registration<\/jats:title>\nThis study is registered as PROSPERO CRD42020168667.<\/jats:p>\n<\/jats:sec>\nFunding<\/jats:title>\nThis award was funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme (NIHR award ref: NIHR128128) and is published in full in Health Technology Assessment<\/jats:italic>; Vol. 28, No. 67. See the NIHR Funding and Awards website for further award information.<\/jats:p>\n<\/jats:sec>","DOI":"10.3310\/jtnt0476","type":"journal-article","created":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T15:11:59Z","timestamp":1728918719000},"page":"1-100","update-policy":"https:\/\/doi.org\/10.3310\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Care models for coexisting serious mental health and alcohol\/drug conditions: the RECO realist evidence synthesis and case study evaluation"],"prefix":"10.3310","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4480-0806","authenticated-orcid":true,"given":"Elizabeth","family":"Hughes","sequence":"first","affiliation":[{"name":"School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, 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