{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T05:13:59Z","timestamp":1791954839541,"version":"4.3.4"},"reference-count":29,"publisher":"The Japanese Society for Medical Mycology","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Mycology Journal"],"published-print":{"date-parts":[[2016]]},"DOI":"10.3314\/mmj.16-00002","type":"journal-article","created":{"date-parts":[[2016,8,30]],"date-time":"2016-08-30T22:18:01Z","timestamp":1472595481000},"page":"E41-E46","source":"Crossref","is-referenced-by-count":26,"title":["Identification of Disseminated Cryptococcosis Using MALDI-TOF MS and Clinical Evaluation"],"prefix":"10.3314","volume":"57","author":[{"given":"Norihito","family":"Tarumoto","sequence":"first","affiliation":[{"name":"Department of Infectious Disease and Infection Control, Saitama Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Sakai","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease and Infection Control, Saitama Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Kodana","sequence":"additional","affiliation":[{"name":"Clinical Laboratory Medicine, Saitama Medical University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tohru","family":"Kawamura","sequence":"additional","affiliation":[{"name":"Clinical Laboratory Medicine, Saitama Medical University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Ohno","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease and Infection Control, Saitama Medical Center, Saitama Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigefumi","family":"Maesaki","sequence":"additional","affiliation":[{"name":"Clinical Laboratory Medicine, Saitama Medical University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1842","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Perfect JR, Dismukes WE, Dromer F, Goldman DL, Graybill JR, Hamill RJ, Harrison TS, Larsen RA, Lortholary O, Nguyen MH, Pappas PG, Powderly WG, Singh N, Sobel JD, Sorrell TC: Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of america. Clin Infect Dis 50: 291-322, 2010.","DOI":"10.1086\/649858"},{"key":"2","unstructured":"2) Mycoses Forum Task Force on the Guidelines of Deep-Seated Mycoses: Guidelines for the Diagnosis and Management of Deep-Seated Mycoses 2014. Kyowa Kikaku Ltd, Tokyo, Japan, 2014."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Arendrup MC, Boekhout T, Akova M, Meis JF, Cornely OA, Lortholary O: ESCMID and ECMM joint clinical guidelines for the diagnosis and management of rare invasive yeast infections. Clin Microbiol Infect 20 Suppl 3: 76-98, 2014.","DOI":"10.1111\/1469-0691.12360"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Bratton EW, El Husseini N, Chastain CA, Lee MS, Poole C, Stürmer T, Juliano JJ, Weber DJ, Perfect JR: Comparison and temporal trends of three groups with cryptococcosis: HIV-infected, solid organ transplant, and HIV-negative\/non-transplant. PLoS One 7: e43582, 2012.","DOI":"10.1371\/journal.pone.0043582"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Brizendine KD, Baddley JW, Pappas PG: Predictors of mortality and differences in clinical features among patients with Cryptococcosis according to immune status. PLoS One 8: e60431, 2013.","DOI":"10.1371\/journal.pone.0060431"},{"key":"6","doi-asserted-by":"crossref","unstructured":"7) Mihara T, Izumikawa K, Kakeya H, Ngamskulrungroj P, Umeyama T, Takazono T, Tashiro M, Nakamura S, Imamura Y, Miyazaki T, Ohno H, Yamamoto Y, Yanagihara K, Miyzaki Y, Kohno S: Multilocus sequence typing of Cryptococcus neoformans<\/I> in non-HIV associated cryptococcosis in Nagasaki, Japan. Med Mycol 51: 252-260, 2013.","DOI":"10.3109\/13693786.2012.708883"},{"key":"7","doi-asserted-by":"crossref","unstructured":"8) Umeyama T, Ohno H, Minamoto F, Takagi T, Tanamachi C, Tanabe K, Kaneko Y, Yamagoe S, Kishi K, Fujii T, Takemura H, Watanabe H, Miyazaki Y: Determination of epidemiology of clinically isolated Cryptococcus neoformans<\/I> strains in Japan by multilocus sequence typing. Jpn J Infect Dis 66: 51-55, 2013.","DOI":"10.7883\/yoken.66.51"},{"key":"8","doi-asserted-by":"crossref","unstructured":"9) Okamoto K, Hatakeyama S, Itoyama S, Nukui Y, Yoshino Y, Kitazawa T, Yotsuyanagi H, Ikeda R, Sugita T, Koike K: Cryptococcus gattii<\/I> genotype VGIIa infection in man, Japan, 2007. Emerg Infect Dis 16: 1155-1157, 2010.","DOI":"10.3201\/eid1607.100106"},{"key":"9","doi-asserted-by":"crossref","unstructured":"10) Nakashima K, Akamatsu H, Endo M, Kawamura I, Nakajima T, Takahashi T: Endobronchial cryptococcosis induced by Cryptococcus gattii<\/I> mimicking metastatic lung cancer. Respirol Case Rep 2: 108-110, 2014.","DOI":"10.1002\/rcr2.64"},{"key":"10","doi-asserted-by":"crossref","unstructured":"11) Kawamura I, Kamei K, Yarita K, Ohkusu M, Ito K, Tsukahara M, Honda M, Nakashima K, Akamatsu H, Kurai H: Cryptococcus gattii<\/I> genotype VGIIb infection in Japan. Med Mycol J 55: E51-54, 2014.","DOI":"10.3314\/mmj.55.E51"},{"key":"11","doi-asserted-by":"crossref","unstructured":"12) Khawcharoenporn T, Apisarnthanarak A, Mundy LM: Non-neoformans cryptococcal infections: a systematic review. Infection 35: 51-58, 2007.","DOI":"10.1007\/s15010-007-6142-8"},{"key":"12","doi-asserted-by":"crossref","unstructured":"13) Bernal-Martinez L, Gomez-Lopez A, Castelli MV, Mesa-Arango AC, Zaragoza O, Rodriguez-Tudela JL, Cuenca-Estrella M: Susceptibility profile of clinical isolates of non-Cryptococcus neoformans\/<\/I> non-Cryptococcus gattii Cryptococcus<\/I> species and literature review. Med Mycol 48: 90-96, 2010.","DOI":"10.3109\/13693780902756073"},{"key":"13","doi-asserted-by":"crossref","unstructured":"14) Marklein G, Josten M, Klanke U, Müller E, Horré R, Maier T, Wenzel T, Kostrzewa M, Bierbaum G, Hoerauf A, Sahl HG: Matrix-assisted laser desorption ionization-time of flight mass spectrometry for fast and reliable identification of clinical yeast isolates. J Clin Microbiol 47: 2912-2917, 2009.","DOI":"10.1128\/JCM.00389-09"},{"key":"14","doi-asserted-by":"crossref","unstructured":"15) McTaggart LR, Lei E, Richardson SE, Hoang L, Fothergill A, Zhang SX: Rapid identification of Cryptococcus neoformans<\/I> and Cryptococcus gattii<\/I> by matrix-assisted laser desorption ionization-time of flight mass spectrometry. J Clin Microbiol 49: 3050-3053, 2011.","DOI":"10.1128\/JCM.00651-11"},{"key":"15","doi-asserted-by":"crossref","unstructured":"16) Bader O, Weig M, Taverne-Ghadwal L, Lugert R, Gross U, Kuhns M: Improved clinical laboratory identification of human pathogenic yeasts by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Clin Microbiol Infect 17: 1359-1365, 2011.","DOI":"10.1111\/j.1469-0691.2010.03398.x"},{"key":"16","unstructured":"17) Clinical and laboratory standards institute: Reference method for broth dilution. antifungal susceptibility testing of yeasts, approved standard-third edition. Wayne, PA, 2008."},{"key":"17","doi-asserted-by":"crossref","unstructured":"18) Pfaller MA, Lodge JK, Ghannoum MA: Drug resistance in cryptococcus<\/I>: epidemiology and Molecular mechanisms. In Cryptococcus<\/I> (Heitman J, Kozel TR, Kwon-Chung KJ, Perfect JR, Casadevall A eds), pp.203-216, Washington, DC, ASM press, 2011.","DOI":"10.1128\/9781555816858.ch16"},{"key":"18","doi-asserted-by":"crossref","unstructured":"19) Singer LM, Meyer W, Firacative C, Thompson GR 3rd, Samitz E, Sykes JE: Antifungal drug susceptibility and phylogenetic diversity among Cryptococcus<\/I> isolates from dogs and cats in North America. J Clin Microbiol 52: 2061-2070, 2014.","DOI":"10.1128\/JCM.03392-13"},{"key":"19","doi-asserted-by":"crossref","unstructured":"20) Smith KD, Achan B, Hullsiek KH, McDonald TR, Okagaki LH, Alhadab AA, Akampurira A, Rhein JR, Meya DB, Boulware DR, Nielsen K: Increased Antifungal Drug Resistance in Clinical Isolates of Cryptococcus neoformans<\/I> in Uganda. Antimicrob Agents Chemother 59: 7197-7204, 2015.","DOI":"10.1128\/AAC.01299-15"},{"key":"20","doi-asserted-by":"crossref","unstructured":"21) Witt MD, Lewis RJ, Larsen RA, Milefchik EN, Leal MA, Haubrich RH, Richie JA, Edwards JE Jr., Ghannoum MA: Identification of patients with acute AIDS-associated cryptococcal meningitis who can be effectively treated with fluconazole: the role of antifungal susceptibility testing. Clin Infect Dis 22: 322-328, 1996.","DOI":"10.1093\/clinids\/22.2.322"},{"key":"21","doi-asserted-by":"crossref","unstructured":"22) Aller AI, Martin-Mazuelos E, Lozano F, Gomez-Mateos J, Steele-Moore L, Holloway WJ, Gutiérrez MJ, Recio FJ, Espinel-Ingroff A: Correlation of fluconazole MICs with clinical outcome in cryptococcal infection. Antimicrob Agents Chemother 44: 1544-1548, 2000.","DOI":"10.1128\/AAC.44.6.1544-1548.2000"},{"key":"22","doi-asserted-by":"crossref","unstructured":"23) Lee CH, Chang TY, Liu JW, Chen FJ, Chien CC, Tang YF, Lu CH: Correlation of anti-fungal susceptibility with clinical outcomes in patients with cryptococcal meningitis. BMC Infect Dis 12: 361, 2012.","DOI":"10.1186\/1471-2334-12-361"},{"key":"23","doi-asserted-by":"crossref","unstructured":"24) Bicanic T, Harrison T, Niepieklo A, Dyakopu N, Meintjes G: Symptomatic relapse of HIV-associated cryptococcal meningitis after initial fluconazole monotherapy: the role of fluconazole resistance and immune reconstitution. Clin Infect Dis 43: 1069- 1073, 2006.","DOI":"10.1086\/507895"},{"key":"24","doi-asserted-by":"crossref","unstructured":"25) Yan Y, He Y, Maier T, Quinn C, Shi G, Li H, Stratton CW, Kostrzewa M, Tang YW: Improved identification of yeast species directly from positive blood culture media by combining Sepsityper specimen processing and Microflex analysis with the matrix-assisted laser desorption ionization Biotyper system. J Clin Microbiol 49: 2528-2532, 2011.","DOI":"10.1128\/JCM.00339-11"},{"key":"25","doi-asserted-by":"crossref","unstructured":"26) De Carolis E, Vella A, Florio AR, Posteraro P, Perlin DS, Sanguinetti M, Posteraro B: Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry for caspofungin susceptibility testing of Candida<\/I> and Aspergillus<\/I> species. J Clin Microbiol 50: 2479-2483, 2012.","DOI":"10.1128\/JCM.00224-12"},{"key":"26","doi-asserted-by":"crossref","unstructured":"27) Vella A, De Carolis E, Vaccaro L, Posteraro P, Perlin DS, Kostrzewa M, Posteraro B, Sanguinetti M: Rapid antifungal susceptibility testing by matrix-assisted laser desorption ionization-time of flight mass spectrometry analysis. J Clin Microbiol 51: 2964-2969, 2013.","DOI":"10.1128\/JCM.00903-13"},{"key":"27","doi-asserted-by":"crossref","unstructured":"28) Huang AM, Newton D, Kunapuli A, Gandhi TN, Washer LL, Isip J, Collins CD, Nagel JL: Impact of rapid organism identification via matrix-assisted laser desorption\/ionization time-of-flight combined with antimicrobial stewardship team intervention in adult patients with bacteremia and candidemia. Clin Infect Dis 57: 1237-1245, 2013.","DOI":"10.1093\/cid\/cit498"},{"key":"28","doi-asserted-by":"crossref","unstructured":"29) Dromer F, Moulignier A, Dupont B, Guého E, Baudrimont M, Improvisi L, Provost F, Gonzalez-Canali G: Myeloradiculitis due to Cryptococcus curvatus<\/I> in AIDS. AIDS 9: 395-396, 1995.","DOI":"10.1097\/00002030-199509040-00012"},{"key":"29","doi-asserted-by":"crossref","unstructured":"30) Shimokawa O, Niimi M, Kikuchi K, Saito M, Kajiwara H, Yoshida S: Relationship between MIC and minimum sterol 14α-demethylation-inhibitory concentration as a factor in evaluating activities of azoles against various fungal species. J Clin Microbiol 43: 5547-5549, 2005.","DOI":"10.1128\/JCM.43.11.5547-5549.2005"}],"container-title":["Medical Mycology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/mmj\/57\/3\/57_16-00002\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T21:40:40Z","timestamp":1498340440000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/mmj\/57\/3\/57_16-00002\/_article\/-char\/ja\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.3314\/mmj.16-00002","relation":{},"ISSN":["2185-6486","2186-165X"],"issn-type":[{"value":"2185-6486","type":"print"},{"value":"2186-165X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}