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Emerg Infect Dis 21: 1041-1044, 2015.","DOI":"10.3201\/eid2106.140717"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Hagiwara D, Watanabe A, Kamei K, Goldman GH: Epidemiological and genomic landscape of azole resistance mechanisms in <i>Aspergillus<\/i> fungi. Front Microbiol 7: 1382, 2016.","DOI":"10.3389\/fmicb.2016.01382"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Chowdhary A, Kathuria S, Xu J, Meis JF: Emergence of azole-resistant <i>Aspergillus fumigatus<\/i> strains due to agricultural azole use creates an increasing threat to human health. PLoS Pathog 9: e1003633, 2013.","DOI":"10.1371\/journal.ppat.1003633"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) van Ingen J, van der Lee HA, Rijs TA, Zoll J, Leenstra T, Melchers WJ, Verweij PE: Azole, polyene and echinocandin MIC distributions for wild-type, TR34\/L98H and TR46\/Y121F\/T289A <i>Aspergillus fumigatus<\/i> isolates in the Netherlands. J Antimicrob Chemother 70: 178-181, 2015.","DOI":"10.1093\/jac\/dku364"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Lockhart SR, Frade JP, Etienne KA, Pfaller MA, Diekema DJ, Balajee SA: Azole resistance in <i>Aspergillus fumigatus<\/i> isolates from the ARTEMIS global surveillance study is primarily due to the TR\/L98H mutation in the <i>cyp51A<\/i> gene. Antimicrob Agents Chemother 55: 4465-4468, 2011.","DOI":"10.1128\/AAC.00185-11"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Hagiwara D, Takahashi H, Fujimoto M, Sugahara M, Misawa Y, Gonoi T, Itoyama S, Watanabe A, Kamei K: Multi-azole resistant <i>Aspergillus fumigatus<\/i> harboring Cyp51A TR46\/Y121F\/T289A isolated in Japan. J Infect Chemother 22: 577-579, 2016.","DOI":"10.1016\/j.jiac.2016.01.015"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Wu CJ, Wang HC, Lee JC, Lo HJ, Dai CT, Chou PH, Ko WC, Chen YC: Azole-resistant <i>Aspergillus fumigatus<\/i> isolates carrying TR<sub>34<\/sub>\/L98H mutations in Taiwan. Mycoses 58: 544-549, 2015.","DOI":"10.1111\/myc.12354"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Lee HJ, Cho SY, Lee DG, Park C, Chun HS, Park YJ: TR<sub>34<\/sub>\/L98H mutation in CYP51A gene in <i>Aspergillus fumigatus<\/i> clinical isolates during posaconazole prophylaxis: First case in Korea. Mycopathologia 183: 731-736, 2018.","DOI":"10.1007\/s11046-018-0271-8"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Chen J, Li H, Li R, Bu D, Wan Z: Mutations in the <i>cyp51A<\/i> gene and susceptibility to itraconazole in <i>Aspergillus fumigatus<\/i> serially isolated from a patient with lung aspergilloma. J Antimicrob Chemother 55: 31-37, 2005.","DOI":"10.1093\/jac\/dkh507"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Chen Y, Lu Z, Zhao J, et al: Epidemiology and molecular characterizations of azole resistance in clinical and environmental <i>Aspergillus fumigatus<\/i> isolates from China. Antimicrob Agents Chemother 60: 5878-5884, 2016.","DOI":"10.1128\/AAC.01005-16"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Liu M, Zeng R, Zhang L, Li D, Lv G, Shen Y, Zheng H, Zhang Q, Zhao J, Zheng N, Liu W: Multiple <i>cyp51A<\/i>-based mechanisms identified in azole-resistant isolates of <i>Aspergillus fumigatus<\/i> from China. Antimicrob Agents Chemother 59: 4321-4325, 2015.","DOI":"10.1128\/AAC.00003-15"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Ren J, Jin X, Zhang Q, Zheng Y, Lin D, Yu Y: Fungicides induced triazole-resistance in <i>Aspergillus fumigatus<\/i> associated with mutations of TR46\/Y121F\/T289A and its appearance in agricultural fields. J Hazard Mater 326: 54-60, 2017.","DOI":"10.1016\/j.jhazmat.2016.12.013"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Zhang M, Feng CL, Chen F, He Q, Su X, Shi Y: Triazole resistance in <i>Aspergillus fumigatus<\/i> clinical isolates obtained in Nanjing, China. Chin Med J (Engl) 130: 665-668, 2017.","DOI":"10.4103\/0366-6999.201609"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Asano M, Kano R, Makimura K, Hasegawa A, Kamata H: Molecular typing and <i>in-vitro<\/i> activity of azoles against clinical isolates of <i>Aspergillus fumigatus<\/i> and <i>A. niger<\/i> in Japan. J Infect Chemother 17: 483-486, 2011.","DOI":"10.1007\/s10156-010-0202-1"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Tashiro M, Izumikawa K, Hirano K, et al: Correlation between triazole treatment history and susceptibility in clinically isolated <i>Aspergillus fumigatus<\/i>. Antimicrob Agents Chemother 56: 4870-4875, 2012.","DOI":"10.1128\/AAC.00514-12"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Toyotome T, Fujiwara T, Kida H, Matsumoto M, Wada T, Komatsu R: Azole susceptibility in clinical and environmental isolates of <i>Aspergillus fumigatus<\/i> from eastern Hokkaido, Japan. J Infect Chemother 22: 648-650, 2016.","DOI":"10.1016\/j.jiac.2016.03.002"},{"key":"20","unstructured":"20) Hagiwara D, Arai T, Takahashi H, Kusuya Y, Watanabe A, Kamei K: Clinical isolates of non-<i>cyp51A<\/i> azole-resistant <i>Aspergillus fumigatus<\/i> harboring a mutation in <i>hmg1<\/i> gene encoding HMG-CoA reductase. 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Med Mycol J 58: E67-E70, 2017.","DOI":"10.3314\/mmj.17-00002"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Kikuchi K, Watanabe A, Ito J, Oku Y, Wuren T, Taguchi H, Yarita K, Muraosa Y, Yahiro M, Yaguchi T, Kamei K: Antifungal susceptibility of <i>Aspergillus fumigatus<\/i> clinical isolates collected from various areas in Japan. J Infect Chemother 20: 336-338, 2014.","DOI":"10.1016\/j.jiac.2014.01.003"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Hagiwara D, Takahashi H, Watanabe A, Takahashi-Nakaguchi A, Kawamoto S, Kamei K, Gonoi T: Whole-genome comparison of <i>Aspergillus fumigatus<\/i> strains serially isolated from patients with aspergillosis. J Clin Microbiol 52: 4202-4209, 2014.","DOI":"10.1128\/JCM.01105-14"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Hagiwara D, Miura D, Shimizu K, Paul S, Ohba A, Gonoi T, Watanabe A, Kamei K, Shintani T, Moye-Rowley WS, Kawamoto S, Gomi K: A Novel Zn2-Cys6 transcription factor AtrR plays a key role in an azole resistance mechanism of <i>Aspergillus fumigatus<\/i> by co-regulating <i>cyp51A<\/i> and <i>cdr1B<\/i> expressions. PLoS Pathog 13: e1006096, 2017.","DOI":"10.1371\/journal.ppat.1006096"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Umeyama T, Hayashi Y, Shimosaka H, Inukai T, Yamagoe S, Takatsuka S, Hoshino Y, Nagi M, Nakamura S, Kamei K, Ogawa K, Miyazaki Y: CRISPR\/Cas9 genome editing to demonstrate the contribution of Cyp51A Gly138Ser to azole resistance in <i>Aspergillus fumigatus<\/i>. Antimicrob Agents Chemother 62: e00894-18, 2018.","DOI":"10.1128\/AAC.00894-18"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Wu CJ, Wang HC, Lee JC, Lo HJ, Dai CT, Chou PH, Ko WC, Chen YC: Azole-resistant <i>Aspergillus fumigatus<\/i> isolates carrying TR<sub>34<\/sub>\/L98H mutations in Taiwan. Mycoses 58: 544-549, 2015.","DOI":"10.1111\/myc.12354"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Wang HC, Huang JC, Lin YH, Chen YH, Hsieh MI, Choi PC, Lo HJ, Liu WL, Hsu CS, Shih HI, Wu CJ, Chen YC: Prevalence, mechanisms and genetic relatedness of the human pathogenic fungus <i>Aspergillus fumigatus<\/i> exhibiting resistance to medical azoles in the environment of Taiwan. 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