{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T10:43:28Z","timestamp":1792665808536,"version":"4.5.0"},"reference-count":33,"publisher":"The Japanese Society for Medical Mycology","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Mycology Journal"],"published-print":{"date-parts":[[2019]]},"DOI":"10.3314\/mmj.19-00001","type":"journal-article","created":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T22:08:41Z","timestamp":1559254121000},"page":"29-37","source":"Crossref","is-referenced-by-count":15,"title":["Mild Heat Stress Affects on the Cell Wall Structure in &lt;i&gt;Candida albicans&lt;\/i&gt; Biofilm"],"prefix":"10.3314","volume":"60","author":[{"given":"Shojiro","family":"Ikezaki","sequence":"first","affiliation":[{"name":"Section of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College"},{"name":"Section of Oral Surgery, Department of Oral and Maxillofacial Surgery, Fukuoka Dental College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamaki","family":"Cho","sequence":"additional","affiliation":[{"name":"Section of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-ichi","family":"Nagao","sequence":"additional","affiliation":[{"name":"Section of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonoko","family":"Tasaki","sequence":"additional","affiliation":[{"name":"Section of Dentistry for the Disabled, Department of Oral Growth and Development, Fukuoka Dental College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masashi","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Medical Mycology Research Center, Chiba University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken-ichi","family":"Arita-Morioka","sequence":"additional","affiliation":[{"name":"Section of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanae","family":"Yasumatsu","sequence":"additional","affiliation":[{"name":"Section of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroji","family":"Chibana","sequence":"additional","affiliation":[{"name":"Medical Mycology Research Center, Chiba University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuro","family":"Ikebe","sequence":"additional","affiliation":[{"name":"Section of Oral Surgery, Department of Oral and Maxillofacial Surgery, Fukuoka Dental College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiko","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Section of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1842","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Calderone RA, Clancy CJ (eds): <i>Candida<\/i> and candidiasis. ASM Press, Washington, 2011.","DOI":"10.1128\/9781555817176"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Hanson DF: Fever, temperature, and the immune response. Ann N Y Acad Sci 813: 453-464, 1997.","DOI":"10.1111\/j.1749-6632.1997.tb51733.x"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Shui C, Scutt A: Mild heat shock induces proliferation, alkaline phosphatase activity, and mineralization in human bone marrow stromal cells and Mg-63 cells <i>in vitro<\/i>. J Bone Miner Res 16: 731-741, 2001.","DOI":"10.1359\/jbmr.2001.16.4.731"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Park HG, Han SI, Oh SY, Kang HS: Cellular responses to mild heat stress. Cell Mol Life Sci 62: 10-23, 2005.","DOI":"10.1007\/s00018-004-4208-7"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Yamaguchi T, Suzuki T, Arai H, Tanabe S, Atomi Y: Continuous mild heat stress induces differentiation of mammalian myoblasts, shifting fiber type from fast to slow. Am J Physiol Cell Physiol 298: C140-C148, 2010.","DOI":"10.1152\/ajpcell.00050.2009"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Griffin RJ, Dings RP, Jamshidi-Parsian A, Song CW: Mild temperature hyperthermia and radiation therapy: role of tumor vascular thermotolerance and relevant physiological factors. Int J Hyperthermia 26: 256-263, 2010.","DOI":"10.3109\/02656730903453546"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Hasday JD, Fairchild KD, Shanholtz C: The role of fever in the infected host. Microbes Infect 2: 1891-1904, 2000.","DOI":"10.1016\/S1286-4579(00)01337-X"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Cowen LE, Lindquist S: Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi. Science 309: 2185-2189, 2005.","DOI":"10.1126\/science.1118370"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Cho T, Nagao J, Imayoshi R, Kodama J, Morotomi T, Kaminishi H: <i>In vitro<\/i> efficacy of continuous mild heat stress on the antifungal susceptibility of <i>Candida albicans<\/i> biofilm formation. Biol Pharm Bull 35: 1371-1373, 2012.","DOI":"10.1248\/bpb.b12-00228"},{"key":"10","unstructured":"10) Pumeesat P, Muangkaew W, Ampawong S, Luplertlop N: <i>Candida albicans<\/i> biofilm development under increased temperature. New Microbiol 40: 279-283, 2017."},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Zeng R, Li M, Chen Q, Wang L, Zhan P, Wang C, Lv G, Shen Y, Liu W: <i>In Vitro<\/i> analyses of mild heat stress in combination with antifungal agents against <i>Aspergillus fumigatus<\/i> biofilm. Antimicrob Agents Chemother 58: 1443-1450, 2014.","DOI":"10.1128\/AAC.01007-13"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Gillum AM, Tsay EY, Kirsch DR: Isolation of the <i>Candida albicans<\/i> gene for orotidine-5&apos;-phosphate decarboxylase by complementation of S. cerevisiae ura3 and <i>E. coli<\/i> pyrF mutations. Mol Gen Genet 198: 179-182, 1984.","DOI":"10.1007\/BF00328721"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Nakayama H, Mio T, Nagahashi S, Kokado M, Arisawa M, Aoki Y: Tetracycline-regulatable system to tightly control gene expression in the pathogenic fungus <i>Candida albicans<\/i>. Infect Immun 68: 6712-6719, 2000.","DOI":"10.1128\/IAI.68.12.6712-6719.2000"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Chandra J, Mukherjee PK, Leidich SD, Faddoul FF, Hoyer LL, Douglas LJ, Ghannoum MA: Antifungal resistance of candidal biofilms formed on denture acrylic <i>in vitro<\/i>. J Dent Res 80: 903-908, 2001.","DOI":"10.1177\/00220345010800031101"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Umeyama T, Kaneko A, Nagai Y, Hanaoka N, Tanabe K, Takano Y, Niimi M, Uehara Y: <i>Candida albicans<\/i> protein kinase CaHsl1p regulates cell elongation and virulence. Mol Microbiol 55: 381-395, 2005.","DOI":"10.1111\/j.1365-2958.2004.04405.x"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Reuss O, Vik A, Kolter R, Morschh&auml;user J: The SAT1 flipper, an optimized tool for gene disruption in <i>Candida albicans<\/i>. Gene 341: 119-127, 2004.","DOI":"10.1016\/j.gene.2004.06.021"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Bolstad BM, Irizarry RA, Astrand M, Speed TP: A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 19: 185-193, 2003.","DOI":"10.1093\/bioinformatics\/19.2.185"},{"key":"18","unstructured":"18) Gentleman RC, Carey VJ, Bates DM, et al: Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 5: R80, 2004."},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Quackenbush J: Microarray data normalization and transformation. Nat Genet 32 Suppl: 496-501, 2002.","DOI":"10.1038\/ng1032"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Toyoda M, Cho T, Kaminishi H, Sudoh M, Chibana H: Transcriptional profiling of the early stages of germination in <i>Candida albicans<\/i> by real-time RT-PCR. FEMS Yeast Res 5: 287-296, 2004.","DOI":"10.1016\/j.femsyr.2004.08.004"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408, 2001.","DOI":"10.1006\/meth.2001.1262"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Lan CY, Rodarte G, Murillo LA, Jones T, Davis RW, Dungan J, Newport G, Agabian N: Regulatory networks affected by iron availability in <i>Candida albicans<\/i>. Mol Microbiol 53: 1451-1469, 2004.","DOI":"10.1111\/j.1365-2958.2004.04214.x"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Yamaguchi M, Okada H, Namiki Y: Smart specimen prepara-tion for freeze substitution and serial ultrathin sectioning of yeast cells. J Electron Microsc (Tokyo) 58: 261-266, 2009.","DOI":"10.1093\/jmicro\/dfp013"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Yamaguchi M, Chibana H: A method for obtaining serial ultrathin sections of microorganisms in transmission electron microscopy. J Vis Exp 131: e56235, 2018.","DOI":"10.3791\/56235"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Nagao J, Cho T, Uno J, Ueno K, Imayoshi R, Nakayama H, Chibana H, Kaminishi H: <i>Candida albicans<\/i> Msi3p, a homolog of the <i>Saccharomyces cerevisiae<\/i> Sse1p of the Hsp70 family, is involved in cell growth and fluconazole tolerance. FEMS Yeast Res 12: 728-737, 2012.","DOI":"10.1111\/j.1567-1364.2012.00822.x"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Ene IV, Walker LA, Schiavone M, Lee KK, Martin-Yken H, Dague E, Gow NA, Munro CA, Brown AJ: Cell wall remodeling enzymes modulate fungal cell wall elasticity and osmotic stress resistance. MBio 6: e00986-15, 2015.","DOI":"10.1128\/mBio.00986-15"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Heilmann CJ, Sorgo AG, Mohammadi S, Sosinska GJ, de Koster CG, Brul S, de Koning LJ, Klis FM: Surface stress induces a conserved cell wall stress response in the pathogenic fungus <i>Candida albicans<\/i>. Eukaryot Cell 12: 254-264, 2013.","DOI":"10.1128\/EC.00278-12"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Cappellaro C, Baldermann C, Rachel R, Tanner W: Mating type-specific cell-cell recognition of <i>Saccharomyces cerevisiae<\/i>: cell wall attachment and active sites of a- and &alpha;-agglutinin. EMBO J 13: 4737-4744, 1994.","DOI":"10.1002\/j.1460-2075.1994.tb06799.x"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Levin DE: Regulation of cell wall biogenesis in <i>Saccharomyces cerevisiae<\/i>: the cell wall integrity signaling pathway. Genetics 189: 1145-1175, 2011.","DOI":"10.1534\/genetics.111.128264"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) Pradhan A, Avelar GM, Bain JM, Childers DS, Larcombe DE, Netea MG, Shekhova E, Munro CA, Brown GD, Erwig LP, Gow NAR, Brown AJP: Hypoxia promotes immune evasion by triggering &beta;-glucan masking on the <i>Candida albicans<\/i> cell surface via mitochondrial and cAMP-protein kinase A signaling. MBio 9: e01318-18, 2018.","DOI":"10.1128\/mBio.01318-18"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31) Calderon J, Zavrel M, Ragni E, Fonzi WA, Rupp S, Popolo L: <i>PHR1<\/i>, a pH-regulated gene of <i>Candida albicans<\/i> encoding a glucan-remodelling enzyme, is required for adhesion and invasion. Microbiology 156: 2484-2494, 2010.","DOI":"10.1099\/mic.0.038000-0"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) Popolo L, Degani G, Camilloni C, Fonzi WA: The PHR family: the role of extracellular transglycosylases in shaping <i>Candida albicans<\/i> cells. J Fungi (Basel) 3: 59, 2017.","DOI":"10.3390\/jof3040059"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33) Plaine A, Walker L, Da Costa G, Mora-Montes HM, Mckinnon A, Gow NA, Gaillardin C, Munro CA, Richard ML: Functional analysis of <i>Candida albicans<\/i> GPI-anchored protein: role in cell wall integrity and caspofungin sensitivity. Fungal Genet Biol 45: 1404-1414, 2008.","DOI":"10.1016\/j.fgb.2008.08.003"}],"container-title":["Medical Mycology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/mmj\/60\/2\/60_19-00001\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,16]],"date-time":"2020-12-16T07:12:00Z","timestamp":1608102720000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/mmj\/60\/2\/60_19-00001\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.3314\/mmj.19-00001","relation":{},"ISSN":["2185-6486","2186-165X"],"issn-type":[{"value":"2185-6486","type":"print"},{"value":"2186-165X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]}}}