{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T06:11:25Z","timestamp":1788588685552,"version":"build-2803163510"},"reference-count":21,"publisher":"The Japanese Society for Medical Mycology","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Mycology Journal"],"published-print":{"date-parts":[[2026]]},"DOI":"10.3314\/mmj.25-00043","type":"journal-article","created":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T22:12:42Z","timestamp":1788127962000},"page":"193-197","source":"Crossref","is-referenced-by-count":0,"title":["Refractory Azole-Resistant &lt;i&gt;Candida albicans&lt;\/i&gt; Renal and Perirenal Abscess Requiring Nephrectomy"],"prefix":"10.3314","volume":"67","author":[{"given":"Nobuaki","family":"Mori","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Clinical Infectious Diseases, Showa Medical University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kana","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmaceutics, Faculty of Pharmaceutical Sciences, Doshisha Women\u2019s College of Liberal Arts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosuke","family":"Shoji","sequence":"additional","affiliation":[{"name":"Department of Hospital Pharmaceutics, Showa Medical University School of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emiko","family":"Mura","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Medical Oncology, Showa Medical University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhiko","family":"Oshinomi","sequence":"additional","affiliation":[{"name":"Department of Urology, School of Medicine, Showa Medical University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuyuki","family":"Ohira","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Showa University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Fungal Infection, National Institute of Infectious Diseases, Japan Institute for Health Security"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ami","family":"Koizumi","sequence":"additional","affiliation":[{"name":"Department of Fungal Infection, National Institute of Infectious Diseases, Japan Institute for Health Security"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahito","family":"Oda","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Clinical Infectious Diseases, Showa Medical University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Maeda","sequence":"additional","affiliation":[{"name":"Division of Infection Control Sciences, Department of Clinical Pharmacy, Showa Medical University School of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiko","family":"Ishino","sequence":"additional","affiliation":[{"name":"Division of Infection Control Sciences, Department of Clinical Pharmacy, Showa Medical University School of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Issei","family":"Tokimatsu","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Clinical Infectious Diseases, Showa Medical University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1842","reference":[{"key":"1","unstructured":"1) Rodr\u00edguez Arias EA, Santoya Espinosa LC, Romano JP, Mota MF, Chabay P, Diaz Aguiar P: Bilateral multifocal kidney abscess due to <i>Candida albicans<\/i>. Medicina 83: 832&ndash;5, 2023. [Article in Spanish]"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Govel JC, Seabury RW, Asiago-Reddy EA, Gutierrez RL, Parsels KA, Kufel WD: Evaluation of shorter versus longer antifungal treatment durations for <i>Candida<\/i> spp. urinary tract infections among hospitalized adults. Antimicrob Agents Chemother 69: e0192024, 2025.","DOI":"10.1128\/aac.01920-24"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Pappas PG, Kauffman CA, Andes DR, Clancy CJ, Marr KA, Ostrosky-Zeichner L, et al: Clinical practice guideline for the management of candidiasis: 2016 update by the Infectious Diseases Society of America. Clin Infect Dis 62: e1&ndash;50, 2016.","DOI":"10.1093\/cid\/civ933"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Schelenz S, Ross CN: Limitations of caspofungin in the treatment of obstructive pyonephrosis due to <i>Candida glabrata<\/i> infection. BMC Infect Dis 6: 126, 2006.","DOI":"10.1186\/1471-2334-6-126"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Bays DJ, Jenkins EN, Lyman M, Chiller T, Strong N, Ostrosky-Zeichner L, et al: Epidemiology of invasive candidiasis. Clin Epidemiol 16: 549&ndash;66, 2024.","DOI":"10.2147\/CLEP.S459600"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Kajihara T, Yahara K, Nagi M, Kitamura N, Hirabayashi A, Hosaka Y, et al: Distribution, trends, and antifungal susceptibility of <i>Candida<\/i> species causing candidemia in Japan, 2010-2019: A retrospective observational study based on national surveillance data. Med Mycol 60:  myac071, 2022.","DOI":"10.1093\/mmy\/myac071"},{"key":"7","unstructured":"7) Tanaka E, Fukumoto K, Matsumoto K, Tsuchishita Y, Kusumoto M, Ueno K: Comparison of fiuconazole concentration between in serum and in tissue lnpatient receiving fluconazole lntravenously. TDM Kenkyu 23: 226&ndash;8, 2006. [Article in Japanese]"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Niimi K, Harding DRK, Parshot R, King A, Lun DJ, Decottignies A, et al: Chemosensitization of fluconazole resistance in <i>Saccharomyces cerevisiae<\/i> and pathogenic fungi by a Doctapeptide derivative. Antimicrob Agents Chemother 48: 1256&ndash;71, 2004.","DOI":"10.1128\/AAC.48.4.1256-1271.2004"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Uchida T, Somada A, Kagoshima Y, Konosu T, Oida S: Carbon analogs of antifungal dioxane-triazole derivatives: synthesis and in vitro activities. Bioorg Med Chem Lett 18: 6538&ndash;41, 2008.","DOI":"10.1016\/j.bmcl.2008.10.055"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Azeredo FJ, de Ara\u00fajo BV, Haas SE, Torres B, Pigatto M, de Andrade C, et al: Comparison of fluconazole renal penetration levels in healthy and <i>Candida albicans<\/i>-infected Wistar rats. Antimicrob Agents Chemother 56: 5852&ndash;7, 2012.","DOI":"10.1128\/AAC.01323-12"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Cancela Costa A, Kritikos A, Glampedakis E, Da Silva Pereira Clara J, Schaller F, Mercier T, et al: Antifungal drug penetration in soft tissue abscesses: a comparative analysis. J Antimicrob Chemother 79: 1668&ndash;72, 2024.","DOI":"10.1093\/jac\/dkae162"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Cancela Costa A, Grass F, Andres Cano I, Desgranges F, Delabays C, Kritikos A, et al: Antibacterial and antifungal drug concentrations in intra-abdominal abscesses: a prospective clinical study. Antimicrob Agents Chemother 69: e0117824, 2025.","DOI":"10.1128\/aac.01178-24"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Baddley JW, Patel M, Bhavnani SM, Moser SA, Andes DR: Association of fluconazole pharmacodynamics with mortality in patients with candidemia. Antimicrob Agents Chemother 52: 3022&ndash;8, 2008.","DOI":"10.1128\/AAC.00116-08"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Sasse C, Dunkel N, Sch\u00e4fer T, Schneider S, Dierolf F, Ohlsen K, et al: The stepwise acquisition of fluconazole resistance mutations causes a gradual loss of fitness in <i>Candida albicans<\/i>. Mol Microbiol 86: 539&ndash;56, 2012.","DOI":"10.1111\/j.1365-2958.2012.08210.x"},{"key":"15","unstructured":"15) Hoseinnejad A, Maheronnaghsh M, Taghizadeh Armaki M, Jafarzadeh J, Fatahinia M: Is there a difference in the expression levels of genes responsible for fluconazole resistance in <i>Candida albicans<\/i> isolated from people with different underlying diseases? A systematic review. Curr Med Mycol 11: 1589, 2025."},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Flowers SA, Col\u00f3n B, Whaley SG, Schuler MA, Rogers PD: Contribution of clinically derived mutations in ERG11 to azole resistance in <i>Candida albicans<\/i>. Antimicrob Agents Chemother 59: 450&ndash;60, 2015.","DOI":"10.1128\/AAC.03470-14"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Whaley SG, Berkow EL, Rybak JM, Nishimoto AT, Barker KS, Rogers PD: Azole antifungal resistance in <i>Candida albicans<\/i> and emerging non-<i>albicans Candida<\/i> species. Front Microbiol 7: 2173, 2016.","DOI":"10.3389\/fmicb.2016.02173"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Siegel JF, Smith A, Moldwin R: Minimally invasive treatment of renal abscess. J Urol 155: 52&ndash;5, 1996.","DOI":"10.1016\/S0022-5347(01)66536-4"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Bamberger DM: Outcome of medical treatment of bacterial abscesses without therapeutic drainage: review of cases reported in the literature. Clin Infect Dis 23: 592&ndash;603, 1996.","DOI":"10.1093\/clind\/23.1.592"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Fisher JF, Kavanagh K, Sobel JD, Kauffman CA, Newman CA: <i>Candida<\/i> urinary tract infection: pathogenesis. Clin Infect Dis 52 (Suppl 6): S437&ndash;51, 2011.","DOI":"10.1093\/cid\/cir110"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Rodrigues CF, Rodrigues ME, Henriques M: <i>Candida<\/i> sp. infections in patients with diabetes mellitus. J Clin Med 8: 76, 2019.","DOI":"10.3390\/jcm8010076"}],"container-title":["Medical Mycology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/mmj\/67\/3\/67_193\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T05:12:05Z","timestamp":1788585125000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/mmj\/67\/3\/67_193\/_article"}},"subtitle":["A Case Report and Analysis of Fluconazole Concentration"],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.3314\/mmj.25-00043","relation":{},"ISSN":["2185-6486","2186-165X"],"issn-type":[{"value":"2185-6486","type":"print"},{"value":"2186-165X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}