{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T06:11:57Z","timestamp":1788588717385,"version":"build-2803163510"},"reference-count":15,"publisher":"The Japanese Society for Medical Mycology","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Mycology Journal"],"published-print":{"date-parts":[[2026]]},"DOI":"10.3314\/mmj.26-00002","type":"journal-article","created":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T22:12:43Z","timestamp":1788127963000},"page":"207-211","source":"Crossref","is-referenced-by-count":0,"title":["Anticandidal Efficacy of a Paste Containing Capric Acid and a Lysozyme-Chitosan Oligosaccharide Conjugate"],"prefix":"10.3314","volume":"67","author":[{"given":"Mayu","family":"Miyanohara","sequence":"first","affiliation":[{"name":"Department of Oral Health Science, Tsurumi University School of Dental Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidenori","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Oral Health Science, Tsurumi University School of Dental Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takako","family":"Nakatsuka","sequence":"additional","affiliation":[{"name":"Department of Oral Health Science, Tsurumi University School of Dental Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaaki","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Department of Oral Health Science, Tsurumi University School of Dental Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhiro","family":"Hanada","sequence":"additional","affiliation":[{"name":"Institute of Photochemistry and Photofunctional Materials, University of Shanghai for Science and Technology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Kageshima","sequence":"additional","affiliation":[{"name":"Wako Filter Technology, CO., Ltd."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shouichirou","family":"Hirano","sequence":"additional","affiliation":[{"name":"Wako Filter Technology, CO., Ltd."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takatoshi","family":"Murata","sequence":"additional","affiliation":[{"name":"Department of Oral Health Science, Tsurumi University School of Dental Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1842","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Mun M, Yap T, Alnuaimi AD, Adams GG, McCullough MJ: Oral candidal carriage in asymptomatic patients. Aust Dent J 61: 190&ndash;5, 2016.","DOI":"10.1111\/adj.12335"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Vila T, Sultan AS, Montelongo-Jauregui D, Jabra-Rizk MA: Oral candidiasis: A disease of opportunity. J Fungi (Basel) 6: 15, 2020.","DOI":"10.3390\/jof6010015"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Ger\u00f3s-Mesquita \u00c2, Carvalho-Pereira J, Franco-Duarte R, Alves A, Ger\u00f3s H, Pais C, et al: Oral <i>Candida albicans<\/i> colonization in healthy individuals: prevalence, genotypic diversity, stability along time and transmissibility. J Oral Microbiol 12: 1820292, 2020.","DOI":"10.1080\/20002297.2020.1820292"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Xiao J, Huang X, Alkhers N, Alzamil H, Alzoubi S, Wu TT, et al: <i>Candida albicans<\/i> and early childhood caries: A systematic review and meta-analysis. Caries Res 52: 102&ndash;12, 2018.","DOI":"10.1159\/000481833"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Khadka S, Khan S, King A, Goldberg LR, Crocombe L, Bettiol S: Poor oral hygiene, oral microorganisms and aspiration pneumonia risk in older people in residential aged care: a systematic review. Age Ageing 50: 81&ndash;7, 2021.","DOI":"10.1093\/ageing\/afaa102"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Epstein JB, Pearsall NN, Truelove EL: Quantitative relationships between <i>Candida albicans<\/i> in saliva and the clinical status of human subjects. J Clin Microbiol 12: 475&ndash;6, 1980.","DOI":"10.1128\/jcm.12.3.475-476.1980"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Villa S, Hamideh M, Weinstock A, Qasim MN, Hazbun TR, Sellam A, et al: Transcriptional control of hyphal morphogenesis in <i>Candida albicans<\/i>. FEMS Yeast Res 20: foaa005, 2020.","DOI":"10.1093\/femsyr\/foaa005"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Hayama K, Takahashi M, Yui S, Abe S: Inhibitory effects of several saturated fatty acids and their related fatty alcohols on the growth of <i>Candida albicans<\/i>. Drug Discov Ther 9: 386&ndash;90, 2015.","DOI":"10.5582\/ddt.2015.01062"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Takahashi M, Inoue S, Hayama K, Ninomiya K, Abe S: Inhibition of <i>Candida<\/i> mycelia growth by a medium chain fatty acids, capric acid <i>in vitro<\/i> and its therapeutic efficacy in murine oral candidiasis. Med Mycol J 53: 255&ndash;61, 2012. [Article in Japanese]","DOI":"10.3314\/mmj.53.255"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Kageshima H, Hayama K, Takahashi M, Abe M, Yamada T, Saito A, et al: Inhibition of growth of <i>Candida albicans<\/i> by a lysozyme-chitosan conjugate, LYZOX and its combination with decanoic acid. Med Mycol J 58: J63&ndash;9, 2017. [Article in Japanese]","DOI":"10.3314\/mmj.17-00005"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Song Y, Babiker EE, Usui M, Saito A, Kato A: Emulsifying properties and bactericidal action of chitosan\u2013lysozyme conjugates. Food Res Int 35: 459&ndash;66, 2002.","DOI":"10.1016\/S0963-9969(01)00144-2"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Ragland SA, Criss AK: From bacterial killing to immune modulation: Recent insights into the functions of lysozyme. PLoS Pathog 13: e1006512, 2017.","DOI":"10.1371\/journal.ppat.1006512"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Cheung RC, Ng TB, Wong JH, Chan WY: Chitosan: An update on potential biomedical and pharmaceutical applications. Mar Drugs 13: 5156&ndash;86, 2015.","DOI":"10.3390\/md13085156"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Jadhav A, Mortale S, Halbandge S, Jangid P, Patil R, Gade W, et al: The dietary food components capric acid and caprylic acid inhibit virulence factors in <i>Candida albicans<\/i> through multitargeting. J Med Food 20: 1083&ndash;90, 2017.","DOI":"10.1089\/jmf.2017.3971"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Maziere M, Rompante P, Andrade JC, Rodrigues CF: Are mouthwashes really effective against <i>Candida<\/i> spp.? J Fungi (Basel) 10: 528, 2024.","DOI":"10.3390\/jof10080528"}],"container-title":["Medical Mycology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/mmj\/67\/3\/67_207\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T05:12:04Z","timestamp":1788585124000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/mmj\/67\/3\/67_207\/_article"}},"subtitle":["A Case Series"],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.3314\/mmj.26-00002","relation":{},"ISSN":["2185-6486","2186-165X"],"issn-type":[{"value":"2185-6486","type":"print"},{"value":"2186-165X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}