{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T19:24:02Z","timestamp":1750533842553},"reference-count":19,"publisher":"Tottori University Faculty of Medicine","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Yonago Acta Med."],"published-print":{"date-parts":[[2019]]},"DOI":"10.33160\/yam.2019.09.003","type":"journal-article","created":{"date-parts":[[2019,9,12]],"date-time":"2019-09-12T22:04:17Z","timestamp":1568325857000},"page":"258-262","source":"Crossref","is-referenced-by-count":3,"title":["Nodal Merkel Cell Carcinoma in Head and Neck Lesions with an Unknown                    Primary: A Case Report in Light of the Literature"],"prefix":"10.33160","volume":"62","author":[{"given":"Ryoukichi","family":"Ikeda","sequence":"first","affiliation":[{"name":"Division of Otolaryngology, Tohoku Medical and                            Pharmaceutical University, Sendai 981-0905, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuo","family":"Ohta","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology, Tohoku Medical and                            Pharmaceutical University, Sendai 981-0905, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sachiko","family":"Fukaya","sequence":"additional","affiliation":[{"name":"Division of Pathology, Tohoku Medical and                            Pharmaceutical University, Sendai 981-0905, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumi","family":"Shoji","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology, Tohoku Medical and                            Pharmaceutical University, Sendai 981-0905, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology, Tohoku Medical and                            Pharmaceutical University, Sendai 981-0905, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoya","family":"Noguchi","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology, Tohoku Medical and                            Pharmaceutical University, Sendai 981-0905, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Risako","family":"Kakuta","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology, Tohoku Medical and                            Pharmaceutical University, Sendai 981-0905, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiko","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Division of Molecular Pathology, Department of                            Pathology, Tottori University Faculty of Medicine, Yonago 683-8503,                            Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayoshi","family":"Kiba","sequence":"additional","affiliation":[{"name":"Laboratory of Gastrointestinal Regenerative                            Medicine, Okayama University of Science, Okayama 700-0005,                            Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiro","family":"Murakami","sequence":"additional","affiliation":[{"name":"Division of Pathology, Tohoku Medical and                            Pharmaceutical University, Sendai 981-0905, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Division of Pathology, Tohoku Medical and                            Pharmaceutical University, Sendai 981-0905, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18656","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"1. Toker C. Trabecular carcinoma of the                    skin. Arch Dermatol. 1972;105:107-10. PMID:5009611,                    DOI:10.1001\/archderm.1972.01620040075020","DOI":"10.1001\/archderm.1972.01620040075020"},{"key":"2","doi-asserted-by":"publisher","unstructured":"2. Smith VA, Camp ER, Lentsch EJ. Merkel                    cell carcinoma: identification of prognostic factors unique to tumors located in                    the head and neck based on analysis of SEER data. Laryngoscope.                    2012;122:1283-90. PMID:22522673, DOI:10.1002\/lary.23222","DOI":"10.1002\/lary.23222"},{"key":"3","doi-asserted-by":"publisher","unstructured":"3. Hussain SK, Sundquist J, Hemminki K.                    Incidence trends of squamous cell and rare skin cancers in the Swedish national                    cancer registry point to calendar year and age-dependent increases. J Invest                    Dermatol. 2010;130:1323-8. PMID:20090766,                    DOI:10.1038\/jid.2009.426","DOI":"10.1038\/jid.2009.426"},{"key":"4","unstructured":"4. Huber GF, Khalil M, Falck V, Matthews TW,                    Dort JC. Merkel cell carcinoma with solitary parotid metastasis: diagnostic                    dilemma in the absence of a primary site. J Otolaryngol Head Neck Surg.                    2008;37:E19-21."},{"key":"5","doi-asserted-by":"publisher","unstructured":"5. Pan Z, Chen YY, Wu X, Trisal V,                    Wilczynski SP, Weiss LM, et al. Merkel cell carcinoma of lymph node with unknown                    primary has a significantly lower association with Merkel cell polyomavirus than                    its cutaneous counterpart. Mod Pathol. 2014;27:1182-92. PMID:24406862,                    DOI:10.1038\/modpathol.2013.250","DOI":"10.1038\/modpathol.2013.250"},{"key":"6","doi-asserted-by":"publisher","unstructured":"6. Wong SQ, Waldeck K, Vergara IA, Schr\u00f6der                    J, Madore J, Wilmott JS, et al. UV-Associated Mutations Underlie the Etiology of                    MCV-Negative Merkel Cell Carcinomas. Cancer Res. 2015;75:5228-34. PMID:26627015,                    DOI:10.1158\/0008-5472.CAN-15-1877","DOI":"10.1158\/0008-5472.CAN-15-1877"},{"key":"7","doi-asserted-by":"publisher","unstructured":"7. Wong KKS, Oliver GF. Metastatic Merkel                    cell carcinoma with an unknown primary tumour presenting as lichenoid                    dermatitis. Australas J Dermatol. 2010;51:202-5. PMID:20695861,                    DOI:10.1111\/j.1440-0960.2010.00624.x","DOI":"10.1111\/j.1440-0960.2010.00624.x"},{"key":"8","unstructured":"8. Adel K. El-Naggar JKC, Jennifer R Grandis,                    Takashi Takata, Pieter J Slootweg. WHO Classification of Head &amp; Neck                    Tumours. 4th ed. Geneva: World Health Organization; 2017. 347                    p."},{"key":"9","doi-asserted-by":"publisher","unstructured":"9. Albores-Saavedra J, Batich K,                    Chable-Montero F, Sagy N, Schwartz AM, Henson DE. Merkel cell carcinoma                    demographics, morphology, and survival based on 3870 cases: a population based                    study. J Cutan Pathol. 2010;37:20-7. PMID:19638070,                    DOI:10.1111\/j.1600-0560.2009.01370.x","DOI":"10.1111\/j.1600-0560.2009.01370.x"},{"key":"10","unstructured":"10. Saini AT, Miles BA. Merkel cell carcinoma                    of the head and neck: pathogenesis, current and emerging treatment options.                    OncoTargets Ther. 2015;8:2157-67."},{"key":"11","doi-asserted-by":"publisher","unstructured":"11. Leech SN, Kolar AJO, Barrett PD, Sinclair                    SA, Leonard N. Merkel cell carcinoma can be distinguished from metastatic small                    cell carcinoma using antibodies to cytokeratin 20 and thyroid transcription                    factor 1. J Clin Pathol. 2001;54:727-9. PMID:11533085,                    DOI:10.1136\/jcp.54.9.727","DOI":"10.1136\/jcp.54.9.727"},{"key":"12","doi-asserted-by":"publisher","unstructured":"12. Byrd-Gloster AL, Khoor A, Glass LF,                    Messina JL, Whitsett JA, Livingston SK, et al. Differential expression of                    thyroid transcription factor 1 in small cell lung carcinoma and merkel cell                    tumor. Hum Pathol. 2000;31:58-62. PMID:10665914,                    DOI:10.1016\/S0046-8177(00)80199-9","DOI":"10.1016\/S0046-8177(00)80199-9"},{"key":"13","doi-asserted-by":"publisher","unstructured":"13. Feng H, Shuda M, Chang Y, Moore PS.                    Clonal integration of a polyomavirus in human Merkel cell carcinoma. Science.                    2008;319:1096-100. PMID:18202256, DOI:10.1126\/science.1152586","DOI":"10.1126\/science.1152586"},{"key":"14","doi-asserted-by":"publisher","unstructured":"14. Arora R, Chang Y, Moore PS. MCV and                    Merkel cell carcinoma: a molecular success story. Curr Opin Virol.                    2012;2:489-98. PMID:22710026, DOI:10.1016\/j.coviro.2012.05.007","DOI":"10.1016\/j.coviro.2012.05.007"},{"key":"15","doi-asserted-by":"publisher","unstructured":"15. Chen KT, Papavasiliou P, Edwards K, Zhu                    F, Perlis C, Wu H, et al. A better prognosis for Merkel cell carcinoma of                    unknown primary origin. Am J Surg. 2013;206:752-7. PMID:23835211,                    DOI:10.1016\/j.amjsurg.2013.02.005","DOI":"10.1016\/j.amjsurg.2013.02.005"},{"key":"16","doi-asserted-by":"publisher","unstructured":"16. Tarantola TI, Vallow LA, Halyard MY,                    Weenig RH, Warschaw KE, Weaver AL, et al. Unknown primary Merkel cell carcinoma:                    23 new cases and a review. J Am Acad Dermatol. 2013;68:433-40. PMID:23182060,                    DOI:10.1016\/j.jaad.2012.07.035","DOI":"10.1016\/j.jaad.2012.07.035"},{"key":"17","unstructured":"17. Yaramada P, Lim BS, Flannery CM, Koh SS,                    Yaghsezian H. Merkel cell carcinoma of unknown primary with lymph node and                    mesenteric metastasis involving the pancreas and duodenum. J Gastrointest Oncol.                    2016;7(suppl 1):S66-70."},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Harms KL, Healy MA, Nghiem P, Sober AJ,                    Johnson TM, Bichakjian CK, et al. Analysis of Prognostic Factors from 9387                    Merkel Cell Carcinoma Cases Forms the Basis for the New 8th Edition AJCC Staging                    System. Ann Surg Oncol. 2016;23:3564-71.","DOI":"10.1245\/s10434-016-5266-4"},{"key":"19","doi-asserted-by":"publisher","unstructured":"19. M\u00fcller-Richter UDA, Gesierich A, K\u00fcbler                    AC, Hartmann S, Brands RC. Merkel Cell Carcinoma of the Head and Neck:                    Recommendations for Diagnostics and Treatment. Ann Surg Oncol. 2017;24:3430-7.                    PMID:28762116, DOI:10.1245\/s10434-017-5993-1","DOI":"10.1245\/s10434-017-5993-1"}],"container-title":["Yonago Acta Medica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/yam\/62\/3\/62_2019.09.003\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,14]],"date-time":"2019-09-14T04:22:01Z","timestamp":1568434921000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/yam\/62\/3\/62_2019.09.003\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.33160\/yam.2019.09.003","relation":{},"ISSN":["1346-8049"],"issn-type":[{"value":"1346-8049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]}}}