{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T02:02:22Z","timestamp":1774922542327,"version":"3.50.1"},"reference-count":144,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T00:00:00Z","timestamp":1465171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CA A Cancer J Clinicians"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/www.wileyhealthlearning.com\/acs.aspx\">Answer questions and earn CME\/CNE<\/jats:ext-link>\n                  <\/jats:p>\n                  <jats:p>\n                    In this report, a team of surgical pathologists has provided a review of intraepithelial neoplasia in a host of (but not all) anatomic sites of interest to colleagues in various medical specialties, namely, uterine cervix, ovary, breast, lung, head and neck, skin, prostate, bladder, pancreas, and esophagus. There is more experience with more readily accessible sites (such as the uterine cervix and skin) than with other anatomic sites, and the lack of uniform terminology, together with divergent biology in various sites, makes it difficult to paint a unifying, relevant portrait. The authors' aim was to provide a framework from which to move forward as we care for patients with such precancerous lesions.\n                    <jats:bold>CA Cancer J Clin 2016;66:408\u2013436. \u00a9 2016 American Cancer Society.<\/jats:bold>\n                  <\/jats:p>","DOI":"10.3322\/caac.21350","type":"journal-article","created":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T11:53:01Z","timestamp":1465213981000},"page":"408-436","source":"Crossref","is-referenced-by-count":32,"title":["Current concepts in the diagnosis and pathobiology of intraepithelial neoplasia: A review by organ system"],"prefix":"10.3322","volume":"66","author":[{"given":"Lysandra","family":"Voltaggio","sequence":"first","affiliation":[{"name":"Assistant Professor of Pathology, Department of Pathology Johns Hopkins Medical Institutions Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley","family":"Cimino\u2010Mathews","sequence":"additional","affiliation":[{"name":"Assistant Professor of Pathology, Department of Pathology Johns Hopkins Medical Institutions Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin A.","family":"Bishop","sequence":"additional","affiliation":[{"name":"Associate Professor of Pathology, Department of Pathology Johns Hopkins Medical Institutions Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedram","family":"Argani","sequence":"additional","affiliation":[{"name":"Professor of Pathology, Department of Pathology Johns Hopkins Medical Institutions Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan D.","family":"Cuda","sequence":"additional","affiliation":[{"name":"Assistant Professor of Dermatology, Department of Dermatology Johns Hopkins Medical Institutions Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan I.","family":"Epstein","sequence":"additional","affiliation":[{"name":"Professor of Pathology, Department of Pathology Johns Hopkins Medical Institutions Baltimore MD"},{"name":"Professor of Urology, Brady Urological Institute Johns Hopkins Hospital Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph H.","family":"Hruban","sequence":"additional","affiliation":[{"name":"Professor of Pathology, Department of Pathology Johns Hopkins Medical Institutions Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George J.","family":"Netto","sequence":"additional","affiliation":[{"name":"Professor of Pathology, Department of Pathology Johns Hopkins Medical Institutions Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark H.","family":"Stoler","sequence":"additional","affiliation":[{"name":"Professor of Pathology, Department of Pathology University of Virginia Health System Charlottesville VA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janis M.","family":"Taube","sequence":"additional","affiliation":[{"name":"Associate Professor of Dermatology and Pathology, Department of Dermatology Johns Hopkins Medical Institutions Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Russell","family":"Vang","sequence":"additional","affiliation":[{"name":"Professor of Pathology, Department of Pathology Johns Hopkins Medical Institutions Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William H.","family":"Westra","sequence":"additional","affiliation":[{"name":"Professor of Pathology, Department of Pathology Johns Hopkins Medical Institutions Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth A.","family":"Montgomery","sequence":"additional","affiliation":[{"name":"Professor of Pathology, Department of Pathology Johns Hopkins Medical Institutions Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,6,6]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000288"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200608000-00014"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.143.451"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00695230"},{"issue":"1","key":"e_1_2_14_6_1","first-page":"419","article-title":"Three\u2010dimensional microstructure of gastrointestinal tumors. 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