{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T05:14:44Z","timestamp":1788326084362,"version":"build-2803163510"},"reference-count":0,"publisher":"Bangladesh Journals Online (JOL)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bangladesh Med Res Counc Bull"],"abstract":"<jats:p>Background: Tazarotene is a new 3rd generation topical acetylenic retinoid. It normalizes keratinocyte differentiation, reduces keratinocyte proliferation and decreases expression of inflammatory markers. Tazarotene was approved by US FDA in 1997 for acne vulgaris.Objectives: To evaluate the efficacy and safety of topical tazarotene 0.1% cream in the treatment of facial acne.Materials and methods: 67 patients with facial acne in the age range of 13-30 years were enrolled in the study. Purposive sampling was done. Patients were treated with topical Tazarotene cream (0.1%) and were instructed to apply the medication as a thin film over the affected area in the evening once daily for 12 weeks. Follow-up was done at 2nd, 4th week, 8th week and at 12th week.Results: Of the 67 patients, 53% got remission, 9% had good response, 34% had poor response and there was no response in 4% of the patients by 12 weeks of treatment. Among the patients, 9 (13.43%) developed mild side effects. Conclusion: Topical tazarotene cream (0.1%) is a effective and safe treatment option for acne vulgaris affecting face. It is mostly effective in grade-1 and grade-2 acne.DOI: 10.3329\/bmrcb.v36i2.6985Bangladesh Med Res Counc Bull 2010; 36: 43-46<\/jats:p>","DOI":"10.3329\/bmrcb.v36i2.6985","type":"journal-article","created":{"date-parts":[[2011,1,28]],"date-time":"2011-01-28T12:32:53Z","timestamp":1296217973000},"page":"43-46","source":"Crossref","is-referenced-by-count":6,"title":["Topical tazarotene cream (0.1%) in the treatment of facial acne: An open clinical trial"],"prefix":"10.3329","volume":"36","author":[{"given":"ASM","family":"Zakaria","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HK","family":"Paul","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MA","family":"Rahman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MT","family":"Islam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AM","family":"Choudhury","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1861","published-online":{"date-parts":[[1970,1,1]]},"container-title":["Bangladesh Medical Research Council Bulletin"],"original-title":[],"link":[{"URL":"https:\/\/www.banglajol.info\/index.php\/BMRCB\/article\/download\/6985\/5302","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.banglajol.info\/index.php\/BMRCB\/article\/download\/6985\/5302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T21:31:48Z","timestamp":1546378308000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.banglajol.info\/index.php\/BMRCB\/article\/view\/6985"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,1,1]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2011,1,28]]}},"URL":"https:\/\/doi.org\/10.3329\/bmrcb.v36i2.6985","relation":{},"ISSN":["2224-7238","0377-9238"],"issn-type":[{"value":"2224-7238","type":"electronic"},{"value":"0377-9238","type":"print"}],"subject":[],"published":{"date-parts":[[1970,1,1]]}}}