{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T05:16:12Z","timestamp":1732684572506,"version":"3.28.2"},"reference-count":0,"publisher":"Nepal Health Research Council","issue":"3","license":[{"start":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T00:00:00Z","timestamp":1678406400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nepal Health Res Counc"],"abstract":"<jats:p>Background: Alopecia Areata is a common non scarring alopecia with autoimmune etiology. In several previous studies, an insufficient level of 25 hydroxyvitamin D had been correlated with various autoimmune diseases. The current study aimed to determine the level of serum 25 hydroxyvitamin D in patients with alopecia areata.Methods: A cross-sectional\u00a0study was conducted on 35 patients with alopecia areata who visited the outpatient department of Dermatology of KIST Medical College and Teaching Hospital, Nepal. A prior approval of the institute review committee was taken. Convenience sampling technique period for 3 months (March 2022-May 2022) was used to include the participants (informed consent was taken; in minors parental consent was prepared). The serum levels of 25 hydroxyvitamin D was estimated using Abbott Architect i1000 SR analyser. Result: In this study, Alopecia Areata was common in the age group of 16\u201330 years (Mean age: 31.65 \u00b1 11.92 Years). The average duration of the disease in Alopecia Areata patients was close to 1 year. This study indicated a lower concentration of 25 hydroxyvitamin D in half of the studied AA patients (51.4%).The number of patches, Severity of Alopecia Tool scoring, serum 25 hydroxyvitamin D level, and age were found to be statistically insignificant with the disease activity. However, a significant positive correlation was found between the Severity of Alopecia Tool score and the number of patches.Conclusions: Although low levels of serum 25 hydroxyvitamin D may be seen among subjects with alopecia areata; No statistical correlation was observed. Hence, a larger study of similar nature is needed in the future to elucidate the exact correlation. Keywords: Alopecia areata; autoimmune; 25 hydroxyvitamin d.<\/jats:p>","DOI":"10.33314\/jnhrc.v20i3.4408","type":"journal-article","created":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T06:48:49Z","timestamp":1732603729000},"page":"746-749","source":"Crossref","is-referenced-by-count":0,"title":["Determination of Serum 25-Hydroxyvitamin D Levels in Patients with Alopecia Areata"],"prefix":"10.33314","volume":"20","author":[{"given":"Manisha","family":"Singh Basukala","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayush","family":"Jha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roji","family":"Dawadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rima","family":"Shrestha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18778","published-online":{"date-parts":[[2023,3,10]]},"container-title":["Journal of Nepal Health Research Council"],"original-title":[],"deposited":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T06:49:14Z","timestamp":1732603754000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnhrc.com.np\/index.php\/jnhrc\/article\/view\/4408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,10]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,3,17]]}},"URL":"https:\/\/doi.org\/10.33314\/jnhrc.v20i3.4408","relation":{},"ISSN":["1999-6217","1727-5482"],"issn-type":[{"value":"1999-6217","type":"electronic"},{"value":"1727-5482","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3,10]]}}}