{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T09:58:36Z","timestamp":1773655116479,"version":"3.50.1"},"reference-count":0,"publisher":"Australian Centre for Disease Control","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Commun Dis Intell (2018)"],"abstract":"<jats:p>The Australian Mycobacterium Reference Laboratory Network (AMRLN) collects and analyses laboratory data on new cases of disease caused by the\u00a0Mycobacterium tuberculosis\u00a0complex. In 2005, a total of 810 cases were identified by bacteriology; an annual reporting rate of 4.0 cases per 100,000 population. Isolates were identified as\u00a0M. tuberculosis\u00a0(n = 806),\u00a0Mycobacterium africanum\u00a0(n=2) and\u00a0Mycobacterium bovis\u00a0(n=2). Fifteen children aged under 10 years had bacteriologically-confirmed tuberculosis. Results of\u00a0in vitro\u00a0drug susceptibility testing were available for all 810 isolates for isoniazid (H), rifampicin (R), ethambutol (E), and pyrazinamide (Z). A total of 74 (9.1%) isolates of\u00a0M. tuberculosis\u00a0were resistant to at least one of these anti-tuberculosis agents. Resistance to at least H and R (defined as multi-drug resistance, MDR) was detected in 12 (1.5 %) isolates; nine were from the respiratory tract (sputum n= 8, bronchoscopy n= 1). Of the 74\u00a0M. tuberculosis\u00a0isolates resistant to at least one of the standard drugs, 67 (90.5 %) were from new cases, 6 from previously treated cases, and no information was available on the remaining case. Eight were Australian-born, 65 were overseas-born, and the country of birth of one was unknown. Of the 65 overseas-born persons with drug resistant disease, 41 (63.1%) were from 4 countries; Vietnam (n=16), Papua New Guinea (n=10), the Philippines (n=9), and India (n=6). A retrospective review of AMRLN data on isolates collected between 2000 and 2005 found that none of 70 MDR-TB isolates met the new definition for extensively drug resistant TB (XDR-TB, i.e. MDR-TB with additional resistance to quinolones and second-line injectable agents).\u00a0Commun Dis Intell\u00a02007;31:80\u201386.<\/jats:p>","DOI":"10.33321\/cdi.2007.31.3","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T23:12:12Z","timestamp":1749597132000},"page":"80-86","source":"Crossref","is-referenced-by-count":0,"title":["Tuberculosis in Australia: bacteriologically confirmed cases and drug resistance, 2005"],"prefix":"10.33321","volume":"31","author":[{"given":"Richard","family":"Lumb","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Bastian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"Gilpin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Jelfs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terillee","family":"Keehner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aina","family":"Sievers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Australian Mycobacterium Reference Laboratory Network","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18788","published-online":{"date-parts":[[2007,3,1]]},"container-title":["Communicable Diseases Intelligence"],"original-title":[],"link":[{"URL":"https:\/\/ojs.cdi.cdc.gov.au\/index.php\/cdi\/article\/download\/1689\/2762","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ojs.cdi.cdc.gov.au\/index.php\/cdi\/article\/download\/1689\/2762","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T23:12:48Z","timestamp":1749597168000},"score":1,"resource":{"primary":{"URL":"https:\/\/ojs.cdi.cdc.gov.au\/index.php\/cdi\/article\/view\/1689"}},"subtitle":["A Report of the Australian Mycobacterium Reference Laboratory Network"],"short-title":[],"issued":{"date-parts":[[2007,3,1]]},"references-count":0,"URL":"https:\/\/doi.org\/10.33321\/cdi.2007.31.3","relation":{},"ISSN":["2209-6051"],"issn-type":[{"value":"2209-6051","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,3,1]]}}}