{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T04:58:10Z","timestamp":1783400290472,"version":"3.54.6"},"reference-count":0,"publisher":"Australian Centre for Disease Control","license":[{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Commun Dis Intell (2018)"],"abstract":"<jats:p>A 4-year-old fully immunised male presented to a regional hospital in the West Kimberley with fever and lethargy. Blood cultures yielded serogroup B\u00a0Neisseria meningitidis,\u00a0resistant to benzylpenicillin (minimum inhibitory concentration (MIC) 1.0\u00a0mg\/L). The patient was treated with intravenous ceftriaxone and made a complete recovery. Although invasive\u00a0N. meningitidis\u00a0isolates with reduced penicillin susceptibility are not uncommon in Australia, this is the first report of a benzylpenicillin-resistant isolate (MIC &gt; 0.5 mg\/L) causing invasive disease. As benzylpenicillin is currently recommended as first line empiric and definitive therapy for invasive meningococcal disease, the emergence of penicillin-resistant\u00a0N. meningitidis\u00a0disease is of concern and emphasises the importance of ongoing surveillance for antimicrobial resistance.\u00a0Commun Dis Intell\u00a02010;34(3):324\u2013326.<\/jats:p>","DOI":"10.33321\/cdi.2010.34.36","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T22:52:33Z","timestamp":1749595953000},"page":"342-344","source":"Crossref","is-referenced-by-count":5,"title":["Penicillin-resistant Neisseria meningitidis bacteraemia, Kimberley region, March 2010"],"prefix":"10.33321","volume":"34","author":[{"given":"Shivanti D","family":"Abeysuriya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J","family":"Speers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jackie","family":"Gardiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronan J","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18788","published-online":{"date-parts":[[2010,9,1]]},"container-title":["Communicable Diseases Intelligence"],"original-title":[],"link":[{"URL":"https:\/\/ojs.cdi.cdc.gov.au\/index.php\/cdi\/article\/download\/1469\/1587","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ojs.cdi.cdc.gov.au\/index.php\/cdi\/article\/download\/1469\/1587","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T22:52:42Z","timestamp":1749595962000},"score":1,"resource":{"primary":{"URL":"https:\/\/ojs.cdi.cdc.gov.au\/index.php\/cdi\/article\/view\/1469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9,1]]},"references-count":0,"URL":"https:\/\/doi.org\/10.33321\/cdi.2010.34.36","relation":{},"ISSN":["2209-6051"],"issn-type":[{"value":"2209-6051","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9,1]]}}}