{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T05:21:43Z","timestamp":1785302503326,"version":"3.55.0"},"reference-count":0,"publisher":"Australian Centre for Disease Control","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Commun Dis Intell (2018)"],"abstract":"<jats:p>Background  We examined trends in tetanus notification, hospitalisation and death data from 2003\u20132019 to assess the impact of adult tetanus booster recommendations in Australia.  Methods  Tetanus notifications and deaths from the National Notifiable Diseases Surveillance System; hospitalisations from the Australian Institute of Health and Welfare National Hospital Morbidity Database; and deaths from the Australian Coordinating Registry were analysed by age group, sex, Aboriginal and Torres Strait Islander status and state\/territory. Annual rates were calculated using Australian Bureau of Statistics mid-year estimated resident populations from 2003\u20132019 as denominators. To assess the impact of a recommended booster dose of reduced antigen content diphtheria\u2013tetanus\u2013acellular pertussis (dTpa) vaccine for adults aged \u2265 65 years, notification, hospitalisation and death rates of tetanus per 100,000 population were compared pre (2003\u20132012) and post (2013\u20132019) the recommendation\u2019s introduction.  Results  There were 63 notifications of tetanus from 2003\u20132019 with an average annual incidence rate of 0.02\/100,000. Similar to previous studies, the burden of tetanus in the Australian population continues to disproportionately affect the elderly, with those aged \u2265 65 years encompassing 63% (40\/63) of notifications and 100% (11\/11) of the deaths observed in this timeframe. Following the introduction of a recommendation for those aged \u2265 65 years to receive a dTpa booster, average annual notification and hospitalisation rates in those aged \u2265 65 years were significantly lower (notifications: 0.11\/100,000 in 2003\u20132012 and 0.05\/100,000 in 2013\u20132019, p = 0.01; hospitalisations: 0.24\/100,000 in 2003\u20132012 and 0.10\/100,000 in 2013\u20132019, p = 0.01]). The average annual death rate was similar in the two periods (0.002\/100,000), although based on small numbers.  Conclusions  The findings of this analysis suggest a positive impact from the 2013 recommendation. However, the burden is still disproportionately higher in those aged \u2265 65 years and strategies to improve vaccination coverage in older Australians are recommended.<\/jats:p>","DOI":"10.33321\/cdi.2023.47.61","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T21:56:51Z","timestamp":1697666211000},"source":"Crossref","is-referenced-by-count":2,"title":["Australian vaccine preventable disease epidemiological review series: tetanus 2003\u20132019"],"prefix":"10.33321","volume":"47","author":[{"given":"Eliora SG","family":"Morris","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditi","family":"Dey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaitlyn","family":"Vette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harunor","family":"Rashid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Wood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Beard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18788","published-online":{"date-parts":[[2023,10,19]]},"container-title":["Communicable Diseases Intelligence"],"original-title":[],"link":[{"URL":"https:\/\/www1.health.gov.au\/internet\/main\/publishing.nsf\/Content\/458DD8840E8C9332CA25891F0015C89D\/$File\/australian_vaccine_preventable_disease_epidemiological_review_series_tetanus_2003_2019.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T18:43:38Z","timestamp":1749581018000},"score":1,"resource":{"primary":{"URL":"https:\/\/ojs.cdi.cdc.gov.au\/index.php\/cdi\/article\/view\/56"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,19]]},"references-count":0,"URL":"https:\/\/doi.org\/10.33321\/cdi.2023.47.61","relation":{},"ISSN":["2209-6051"],"issn-type":[{"value":"2209-6051","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,19]]}}}