{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T04:18:50Z","timestamp":1783397930817,"version":"3.54.6"},"reference-count":0,"publisher":"Australian Centre for Disease Control","license":[{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Commun Dis Intell (2018)"],"abstract":"<jats:p>The Australian Group on Antimicrobial Resistance (AGAR) performs regular period-prevalence studies to monitor changes in antimicrobial resistance in selected enteric gram-negative pathogens. From 1 January 2024 to 31 December 2024, fifty-five hospitals across Australia participated in the Australian Gram-negative Surveillance Outcome Program (GnSOP).\r\nA total of 10,340 isolates, comprising Enterobacterales (9,376; 90.9%), Pseudomonas aeruginosa (804; 7.7%) and Acinetobacter species (160; 1.4%), were tested using commercial automated methods. The results were analysed using European Committee on Antimicrobial Susceptibility Testing (EUCAST) breakpoints (January 2025). Key resistances reported are to the third-generation cephalosporin ceftriaxone in 14.9% of Escherichia coli and 10.5% of Klebsiella pneumoniae complex isolates. Resistance rates to ciprofloxacin were 15.4% for E. coli; 9.7% for the K. pneumoniae complex; 3.8% for the Enterobacter cloacae complex; and 8.8% for P. aeruginosa. Resistance rates to piperacillin\u2013tazobactam were 7.5%, 10.3%, 25.2%, and 13.6% for the same four species\/complexes, respectively. Thirty-nine Enterobacterales isolates from 38\u00a0patients were shown to harbour a carbapenemase gene: 21 with a blaNDM gene (blaNDM-5 [8]; blaNDM-1 [7]; blaNDM-7 [6]); eight with blaIMP-4; four with a blaOXA-181-like gene (blaOXA-181 [2]; blaOXA-484 [1]; blaOXA-1205 [1]); three with a blaOXA-48-like gene (blaOXA-48 [2]; blaOXA-244); two with blaKPC-2; and one with blaNDM-5 + blaOXA-484. Carbapenemase genes were also detected in two P. aeruginosa isolates (blaNDM-1 [1]; blaGES-5 [1]).<\/jats:p>","DOI":"10.33321\/cdi.2025.49.055","type":"journal-article","created":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T20:53:31Z","timestamp":1763412811000},"source":"Crossref","is-referenced-by-count":3,"title":["Australian Group on Antimicrobial Resistance (AGAR) Australian Gram-negative Surveillance Outcome Program (GnSOP) Bloodstream Infection Annual Report 2024"],"prefix":"10.33321","volume":"49","author":[{"given":"Jan","family":"Bell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Fajardo Lubian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally","family":"Partridge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Gottlieb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Robson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Iredell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Daley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey","family":"Coombs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18788","published-online":{"date-parts":[[2025,11,18]]},"container-title":["Communicable Diseases Intelligence"],"original-title":[],"link":[{"URL":"https:\/\/ojs.cdi.cdc.gov.au\/index.php\/cdi\/article\/download\/3422\/4989","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ojs.cdi.cdc.gov.au\/index.php\/cdi\/article\/download\/3422\/4990","content-type":"application\/vnd.openxmlformats-officedocument.wordprocessingml.document","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ojs.cdi.cdc.gov.au\/index.php\/cdi\/article\/download\/3422\/4989","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T20:53:32Z","timestamp":1763412812000},"score":1,"resource":{"primary":{"URL":"https:\/\/ojs.cdi.cdc.gov.au\/index.php\/cdi\/article\/view\/3422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,18]]},"references-count":0,"URL":"https:\/\/doi.org\/10.33321\/cdi.2025.49.055","relation":{},"ISSN":["2209-6051"],"issn-type":[{"value":"2209-6051","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,18]]}}}