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In this case report, we summarize the presentation, treatment, and outcome of a patient with anti-GBMD with both anti-myeloperoxidase and anti-GBM antibodies, highlighting the safe use of rituximab. We also describe atypical complications in our case, including significant weight loss of unclear etiology and development of recurrent episodes of acute pericalcific arthritis.<\/jats:p>","DOI":"10.3339\/ckd.25.015","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T08:25:16Z","timestamp":1764318316000},"page":"54-61","update-policy":"https:\/\/doi.org\/10.3339\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Anti-glomerular basement membrane disease with concomitant myeloperoxidase antibodies in a pediatric patient: a case report of presentation, treatment and outcome a rare disease"],"prefix":"10.3339","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8809-1311","authenticated-orcid":true,"given":"Yiressy","family":"Pina","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7391-6098","authenticated-orcid":true,"given":"Emily","family":"Frierson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1464-3803","authenticated-orcid":true,"given":"John","family":"Hicks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5736-5578","authenticated-orcid":true,"given":"Partha","family":"Chakraborty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0329-5601","authenticated-orcid":true,"given":"Alvaro","family":"Orjuela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0476-4721","authenticated-orcid":true,"given":"Amit","family":"Thakral","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1891","published-online":{"date-parts":[[2025,11,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1053\/j.akdh.2024.04.007"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2024.103531"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2021.102885"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2021.05.021"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-012-2062-9"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-010-1663-2"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1990.72"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.5414\/cncs111439"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21886"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2019.11.009"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.4103\/1319-2442.202780"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000001179"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2369-14-66"},{"key":"ref14","first-page":"935","volume-title":"Goodpasture\u2019s syndrome in children","author":"Poddar","year":"2010"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-008-0928-5"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-004-1762-z"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/s0272-6386(99)70321-5"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1056\/nejm199312303292708"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002\/jca.22043"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s10140-007-0626-9"}],"container-title":["Childhood Kidney Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/chikd.org\/upload\/ckd-25-015.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:32:34Z","timestamp":1772166754000},"score":1,"resource":{"primary":{"URL":"http:\/\/chikd.org\/journal\/view.php?id=10.3339\/ckd.25.015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,8]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2,28]]}},"URL":"https:\/\/doi.org\/10.3339\/ckd.25.015","relation":{},"ISSN":["2384-0242","2384-0250"],"issn-type":[{"value":"2384-0242","type":"print"},{"value":"2384-0250","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,8]]},"assertion":[{"value":"2025-05-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}