{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T23:18:02Z","timestamp":1782688682525,"version":"3.54.5"},"reference-count":49,"publisher":"Korean Neurosurgical Society","issue":"2","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Korean Neurosurg Soc"],"published-print":{"date-parts":[[2016]]},"DOI":"10.3340\/jkns.2016.59.2.98","type":"journal-article","created":{"date-parts":[[2016,3,8]],"date-time":"2016-03-08T09:52:53Z","timestamp":1457430773000},"page":"98","source":"Crossref","is-referenced-by-count":21,"title":["The Effect of GCSB-5 a New Herbal Medicine on Changes in Pain Behavior and Neuroglial Activation in a Rat Model of Lumbar Disc Herniation"],"prefix":"10.3340","volume":"59","author":[{"given":"Hee Kyung","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, College of Medicine, Catholic University of Daegu, Daegu, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So-Yeon","family":"Kim","sequence":"additional","affiliation":[{"name":"Medical Devices Clinical Trial Center, College of Medicine, Yeungnam University, Daegu, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi Jung","family":"Choi","sequence":"additional","affiliation":[{"name":"Medical Devices Clinical Trial Center, College of Medicine, Yeungnam University, Daegu, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Ok","family":"Baek","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Daegu, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Gyu","family":"Kwak","sequence":"additional","affiliation":[{"name":"Department of Medical Statistics, College of Medicine, Catholic University of Daegu, Daegu, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Ho","family":"Ahn","sequence":"additional","affiliation":[{"name":"Medical Devices Clinical Trial Center, College of Medicine, Yeungnam University, Daegu, Korea."},{"name":"Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Daegu, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1892","reference":[{"key":"10.3340\/jkns.2016.59.2.98_ref1","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1097\/00007632-200205010-00005","volume":"27","author":"Ahn","year":"2002","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref2","doi-asserted-by":"crossref","first-page":"E50","DOI":"10.1097\/00007632-200202010-00003","volume":"27","author":"Anzai","year":"2002","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref3","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1097\/00007632-200208010-00004","volume":"27","author":"Aoki","year":"2002","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref4","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1002\/jor.1100180520","volume":"18","author":"Brisby","year":"2000","journal-title":"J Orthop Res"},{"key":"10.3340\/jkns.2016.59.2.98_ref5","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1097\/00007632-200207010-00006","volume":"27","author":"Burke","year":"2002","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref6","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.expneurol.2009.09.030","volume":"220","author":"Chen","year":"2009","journal-title":"Exp Neurol"},{"key":"10.3340\/jkns.2016.59.2.98_ref7","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.jep.2010.05.020","volume":"130","author":"Chung","year":"2010","journal-title":"J Ethnopharmacol"},{"key":"10.3340\/jkns.2016.59.2.98_ref8","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.pain.2004.03.029","volume":"110","author":"Cuellar","year":"2004","journal-title":"Pain"},{"key":"10.3340\/jkns.2016.59.2.98_ref9","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1002\/neu.480280405","volume":"28","author":"Ding","year":"1995","journal-title":"J Neurobiol"},{"key":"10.3340\/jkns.2016.59.2.98_ref10","first-page":"1777","volume":"32","author":"Ge","year":"2007","journal-title":"Zhongguo Zhong Yao Za Zhi"},{"key":"10.3340\/jkns.2016.59.2.98_ref11","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1097\/BRS.0b013e3181733188","volume":"33","author":"Hatashita","year":"2008","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref12","first-page":"102","volume":"19","author":"Hong","year":"1988","journal-title":"Korean J Pharmacogn"},{"key":"10.3340\/jkns.2016.59.2.98_ref13","doi-asserted-by":"crossref","first-page":"4742","DOI":"10.1523\/JNEUROSCI.16-15-04742.1996","volume":"16","author":"Hua","year":"1996","journal-title":"J Neurosci"},{"key":"10.3340\/jkns.2016.59.2.98_ref14","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1016\/S0960-894X(98)00457-0","volume":"8","author":"Ida","year":"1998","journal-title":"Bioorg Med Chem Lett"},{"key":"10.3340\/jkns.2016.59.2.98_ref15","doi-asserted-by":"crossref","first-page":"2975","DOI":"10.1097\/00007632-200012010-00003","volume":"25","author":"Igarashi","year":"2000","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref16","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/01.brs.0000251437.10545.e9","volume":"32","author":"Ito","year":"2007","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref17","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1007\/s00586-004-0773-6","volume":"14","author":"Kallakuri","year":"2005","journal-title":"Eur Spine J"},{"key":"10.3340\/jkns.2016.59.2.98_ref18","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1097\/00007632-199602010-00003","volume":"21","author":"Kang","year":"1996","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref19","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1097\/00007632-199705150-00003","volume":"22","author":"Kang","year":"1997","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref20","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1097\/00007632-199705150-00004","volume":"22","author":"Kawakami","year":"1997","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref21","doi-asserted-by":"crossref","first-page":"2539","DOI":"10.1097\/00007632-199611150-00002","volume":"21","author":"Kayama","year":"1996","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref22","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1089\/jmf.2008.1239","volume":"12","author":"Kim","year":"2009","journal-title":"J Med Food"},{"key":"10.3340\/jkns.2016.59.2.98_ref23","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.pain.2009.02.006","volume":"143","author":"Kim","year":"2009","journal-title":"Pain"},{"key":"10.3340\/jkns.2016.59.2.98_ref24","doi-asserted-by":"crossref","first-page":"343","DOI":"10.4142\/jvs.2002.3.4.343","volume":"3","author":"Kim","year":"2002","journal-title":"J Vet Sci"},{"key":"10.3340\/jkns.2016.59.2.98_ref25","first-page":"730907","volume":"2012","author":"Kim","year":"2012","journal-title":"Evid Based Complement Alternat Med"},{"key":"10.3340\/jkns.2016.59.2.98_ref26","doi-asserted-by":"crossref","first-page":"E1562","DOI":"10.1097\/BRS.0b013e318210aa10","volume":"36","author":"Kim","year":"2011","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref27","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ejphar.2006.04.046","volume":"540","author":"Lappin","year":"2006","journal-title":"Eur J Pharmacol"},{"key":"10.3340\/jkns.2016.59.2.98_ref28","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1038\/nrn1700","volume":"6","author":"Marchand","year":"2005","journal-title":"Nat Rev Neurosci"},{"key":"10.3340\/jkns.2016.59.2.98_ref29","doi-asserted-by":"crossref","first-page":"549","DOI":"10.4184\/asj.2014.8.5.549","volume":"8","author":"Norimoto","year":"2014","journal-title":"Asian Spine J"},{"key":"10.3340\/jkns.2016.59.2.98_ref30","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.jpain.2004.06.004","volume":"5","author":"Ohtori","year":"2004","journal-title":"J Pain"},{"key":"10.3340\/jkns.2016.59.2.98_ref31","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1097\/00007632-200405150-00006","volume":"29","author":"Ohtori","year":"2004","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref32","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1097\/00007632-199703010-00001","volume":"22","author":"Olmarker","year":"1997","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref33","doi-asserted-by":"crossref","first-page":"2538","DOI":"10.1097\/00007632-199812010-00008","volume":"23","author":"Olmarker","year":"1998","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref34","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1097\/00007632-199318110-00005","volume":"18","author":"Olmarker","year":"1993","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref35","doi-asserted-by":"crossref","first-page":"E753","DOI":"10.1097\/BRS.0b013e3181ef610b","volume":"36","author":"Park","year":"2011","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref36","doi-asserted-by":"crossref","first-page":"18820","DOI":"10.1073\/pnas.0905415106","volume":"106","author":"Patwardhan","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.3340\/jkns.2016.59.2.98_ref37","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1097\/00007632-199711150-00002","volume":"22","author":"Rand","year":"1997","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref38","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1097\/BRS.0b013e3181fa1fca","volume":"36","author":"Sekiguchi","year":"2011","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref39","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1152\/jn.00024.2009","volume":"102","author":"Spicarova","year":"2009","journal-title":"J Neurophysiol"},{"key":"10.3340\/jkns.2016.59.2.98_ref40","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/00007632-199601150-00011","volume":"21","author":"Takahashi","year":"1996","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref41","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.pain.2006.10.007","volume":"129","author":"Takeda","year":"2007","journal-title":"Pain"},{"key":"10.3340\/jkns.2016.59.2.98_ref42","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.tins.2004.12.002","volume":"28","author":"Tsuda","year":"2005","journal-title":"Trends Neurosci"},{"key":"10.3340\/jkns.2016.59.2.98_ref43","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1096\/fasebj.1.2.3111928","volume":"1","author":"Vane","year":"1987","journal-title":"FASEB J"},{"key":"10.3340\/jkns.2016.59.2.98_ref44","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0304-3835(99)00248-7","volume":"145","author":"Wang","year":"1999","journal-title":"Cancer Lett"},{"key":"10.3340\/jkns.2016.59.2.98_ref45","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1152\/physrev.00011.2002","volume":"82","author":"Watkins","year":"2002","journal-title":"Physiol Rev"},{"key":"10.3340\/jkns.2016.59.2.98_ref46","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1038\/nrd1251","volume":"2","author":"Watkins","year":"2003","journal-title":"Nat Rev Drug Discov"},{"key":"10.3340\/jkns.2016.59.2.98_ref47","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0304-3959(97)03369-1","volume":"71","author":"Watkins","year":"1997","journal-title":"Pain"},{"key":"10.3340\/jkns.2016.59.2.98_ref48","doi-asserted-by":"crossref","first-page":"2517","DOI":"10.1097\/00007632-199812010-00006","volume":"23","author":"Yabuki","year":"1998","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3340\/jkns.2016.59.2.98_ref49","first-page":"708","volume":"30","author":"Zhu","year":"2005","journal-title":"Zhongguo Zhong Yao Za Zhi"}],"container-title":["Journal of Korean Neurosurgical Society"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jkns.or.kr\/upload\/pdf\/jkns-59-98.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T09:34:27Z","timestamp":1567676067000},"score":1,"resource":{"primary":{"URL":"http:\/\/jkns.or.kr\/journal\/view.php?doi=10.3340\/jkns.2016.59.2.98"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.3340\/jkns.2016.59.2.98","relation":{},"ISSN":["2005-3711","1598-7876"],"issn-type":[{"value":"2005-3711","type":"print"},{"value":"1598-7876","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}