{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T18:25:37Z","timestamp":1782411937382,"version":"3.54.5"},"reference-count":25,"publisher":"Korean Ophthalmological Society","issue":"6","license":[{"start":{"date-parts":[[2021,9,6]],"date-time":"2021-09-06T00:00:00Z","timestamp":1630886400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["ekjo.org"],"crossmark-restriction":true},"short-container-title":["Korean J Ophthalmol"],"published-print":{"date-parts":[[2021,12,5]]},"abstract":"<jats:p>Purpose: To report the intraoperative corneal pachymetry changes during accelerated corneal cross-linking (A-CXL) in progressive keratoconus patients with thin corneas.Methods: Thirty-six eyes (mean age, 22.26 \u00b1 4.02 years) with progressive keratoconic thin corneas (&lt;400 \u03bcm without epithelium) who underwent A-CXL with ultraviolet (UV)-A (UVA) (9 mW\/cm2) using isotonic riboflavin5-phosphate 0.1% with 1.1% hydroxypropyl methycellulose (RF-HPMC, MedioCROSS M) were included in this retrospective study. Intraoperative corneal pachymetric changes were noted before the procedure, after removal of epithelium, after RF-HPMC instillation, before and after UV irradiation. The mean of corneal pachymetric values were compared statistically.Results: The mean corneal pachymetry reduced from 415.72 \u00b1 29.66 to 369.50 \u00b1 23.45 \u03bcm after removal of the epithelium (p &lt; 0.05). After the application of RF-HPMC solution the mean thinnest corneal pachymetry (TCP) increased to 412.89 \u00b1 26.94 \u03bcm. Statistically significant increase was observed in TCP after saturation with RF-HPMC (p = 0.001). The mean corneal pachymetry before and after UVA irradiation was 419.86 \u00b1 10.41 and 417.47 \u00b1 8.25 \u03bcm, respectively (p &gt; 0.05).Conclusions: Isotonic RF-HPMC lead to a significant increase in intraoperative mean TCP. RF-HPMC seems to be a favorable riboflavin option in keratoconus patients with thin corneas.<\/jats:p>","DOI":"10.3341\/kjo.2021.0111","type":"journal-article","created":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T00:59:40Z","timestamp":1630976380000},"page":"438-442","update-policy":"https:\/\/doi.org\/10.3341\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The Intraoperative Corneal Pachymetry Changes during Accelerated Corneal Cross-linking in Progressive Keratoconus Patients with Thin Corneas"],"prefix":"10.3341","volume":"35","author":[{"given":"Serap Yurtta\u015fer","family":"Ocak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet Serhat","family":"Mangan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa 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