{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T16:46:57Z","timestamp":1779900417860,"version":"3.53.1"},"reference-count":19,"publisher":"Korean Ophthalmological Society","issue":"5","license":[{"start":{"date-parts":[[2022,8,19]],"date-time":"2022-08-19T00:00:00Z","timestamp":1660867200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["ekjo.org"],"crossmark-restriction":true},"short-container-title":["Korean J Ophthalmol"],"published-print":{"date-parts":[[2022,10,5]]},"abstract":"<jats:p>Purpose: To determine the efficacy of immediate pars plana vitrectomy as the primary treatment for acute endophthalmitis in patients with a visual acuity (VA) of hand motion (HM) or better.Methods: A total of 149 patients who were referred to a single center for acute endophthalmitis after cataract surgery over the 13-year study period were retrospectively analyzed. Only patients presenting with a VA of at least HM were included. Patients were initially treated with either primary vitrectomy or intravitreal antibiotic injection alone, and their visual outcomes and reintervention rates after initial treatment were compared.Results: There was no significant difference in the proportion of good (final VA \u226520 \/ 40) and poor (VA \u2264 counting finger) visual outcomes between the groups. However, subgroup analysis of patients with a VA of HM (92 eyes) showed that the incidence of reintervention (14 of 72 eyes [19.4%] vs. 9 of 20 eyes [45.0%]) and poor visual outcomes (10 of 72 eyes [13.9%] vs. 8 of 20 eyes [40.0%]) were lower after prompt vitrectomy than after intravitreal antibiotic injection alone (p = 0.019 and p = 0.022, respectively). For those with a VA of at least counting finger, no significant difference was observed between the groups.Conclusions: For patients with endophthalmitis presenting with a VA of HM, performing a prompt vitrectomy reduced the incidence of reintervention and poor visual outcomes than the administration of intravitreal antibiotics alone. Our results suggest that primary vitrectomy for patients with endophthalmitis presenting with a VA of HM could be more beneficial than intravitreal antibiotic injection alone.<\/jats:p>","DOI":"10.3341\/kjo.2022.0014","type":"journal-article","created":{"date-parts":[[2022,8,22]],"date-time":"2022-08-22T01:12:56Z","timestamp":1661130776000},"page":"390-397","update-policy":"https:\/\/doi.org\/10.3341\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Immediate Vitrectomy for Acute Endophthalmitis in Patients with a Visual Acuity of Hand Motion or Better"],"prefix":"10.3341","volume":"36","author":[{"given":"Jaemin","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyoung Seok","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su 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endophthalmitis after cataract surgery: success of initial therapy, visual outcomes, and related factors","author":"Altan","year":"2009"},{"key":"ref16","first-page":"423","volume-title":"Visual outcome of early vitrectomy and intravitreal antibiotics in acute postsurgical and postintravitreal injection endophthalmitis: European Vitreo-Retinal Society Endophthalmitis Study report two","author":"Soliman","year":"2021"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2017.4276"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3928\/23258160-20170802-05"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-005-0133-1"}],"container-title":["Korean Journal of 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