{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T08:05:04Z","timestamp":1761897904847},"reference-count":19,"publisher":"Korean Ophthalmological Society","issue":"5","license":[{"start":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T00:00:00Z","timestamp":1691625600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["ekjo.org"],"crossmark-restriction":true},"short-container-title":["Korean J Ophthalmol"],"published-print":{"date-parts":[[2023,10,5]]},"abstract":"Purpose: Although the popularity of Descemet membrane endothelial keratoplasty (DMEK) is increased, there is still few clinical studies in Korea. In this study, we aimed to report the initial clinical outcomes of DMEK in patients followed up for more than 6 months.Methods: A total of 96 eyes that underwent DMEK by a single surgeon for Fuchs endothelial corneal dystrophy, pseudophakic bullous keratopathy, or other indications were evaluated for best-corrected visual acuity (BCVA), endothelial cell density (ECD), central corneal thickness (CCT), postoperative complications, and graft survival.Results: The postoperative BCVA significantly increased compared to the preoperative BCVA by 59.4% (1.00 \u00b1 0.77 logarithm of the minimum angle of resolution vs. 0.67 \u00b1 0.76 logarithm of the minimum angle of resolution, <i>p<\/i> < 0.001). The average preoperative ECD was 754 \u00b1 382 cells\/mm<sup>2<\/sup>, increasing to 1,333 \u00b1 562 cells\/mm<sup>2<\/sup> at 3 months (76.8%, <i>p<\/i> < 0.001), 1,334 \u00b1 632 cells\/mm<sup>2<\/sup> at 6 months (76.9%, <i>p<\/i> < 0.001), 1,121 \u00b1 474 cells\/mm<sup>2<\/sup> at 12 months (48.7%, <i>p<\/i> = 0.024), and 972 \u00b1 458 cells\/mm<sup>2<\/sup> at 24 months postoperatively (28.9%, <i>p<\/i> = 0.445). Compared to 3 months, the ECD declined by 15.9% at 12 months (<i>p<\/i> = 0.009) and 27.1% at 24 months postoperatively (<i>p<\/i> = 0.158). The average CCT was 675 \u00b1 113 \u03bcm preoperatively, decreasing to 581 \u00b1 102, 574 \u00b1 101, and 594 \u00b1 94 \u03bcm at 6, 12, and 24 months after DMEK, respectively (<i>p<\/i> < 0.001 between all follow-up time points). Allograft rejection was detected in three (3.1%) and 14 eyes (14.6%) underwent retransplantation at an average of 10.1 \u00b1 8.4 months after DMEK.Conclusions: DMEK is promising for maintaining corneal clarity, low postoperative complication rates, and stable graft longevity.<\/jats:p>","DOI":"10.3341\/kjo.2023.0053","type":"journal-article","created":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T07:01:04Z","timestamp":1691650864000},"page":"373-379","update-policy":"http:\/\/dx.doi.org\/10.3341\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Clinical Outcomes of Descemet Membrane Endothelial Keratoplasty Using a Preloaded Imported Graft"],"prefix":"10.3341","volume":"37","author":[{"given":"Minha","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyung Keun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1893","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-vision-102016-061400"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/icu.0000000000000577"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/ico.0b013e318296e0f7"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3341\/jkos.2021.62.6.848"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0270037"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/ico.0000000000001093"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/ico.0000000000001646"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3341\/jkos.2015.56.10.1489"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/ico.0000000000002120"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2020.04.005"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.07.010"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2011.06.002"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/ico.0000000000001220"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.09.032"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2014.04.023"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1136\/bmjophth-2020-000679"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2016.08.038"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2015.3064"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2016.07.002"}],"container-title":["Korean Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/ekjo.org\/upload\/pdf\/kjo-2023-0053.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/ekjo.org\/journal\/view.php?doi=10.3341\/kjo.2023.0053","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/ekjo.org\/upload\/pdf\/kjo-2023-0053.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T06:28:47Z","timestamp":1697524127000},"score":1,"resource":{"primary":{"URL":"http:\/\/ekjo.org\/journal\/view.php?doi=10.3341\/kjo.2023.0053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,5]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,10]]}},"URL":"https:\/\/doi.org\/10.3341\/kjo.2023.0053","relation":{},"ISSN":["1011-8942","2092-9382"],"issn-type":[{"value":"1011-8942","type":"print"},{"value":"2092-9382","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,5]]},"assertion":[{"value":"2023-05-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-10","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-05","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}