{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T10:46:00Z","timestamp":1777718760517,"version":"3.51.4"},"reference-count":27,"publisher":"Korean Ophthalmological Society","issue":"5","license":[{"start":{"date-parts":[[2024,8,16]],"date-time":"2024-08-16T00:00:00Z","timestamp":1723766400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["ekjo.org"],"crossmark-restriction":true},"short-container-title":["Korean J Ophthalmol"],"published-print":{"date-parts":[[2024,10,5]]},"abstract":"<jats:p>Purpose: To compare corneal higher order aberrations (HOAs) in patients with epiphora caused by unilateral primary acquired nasolacrimal duct obstruction (PANDO) and their fellow eyes.Methods: A total of 122 eyes of 61 patients with unilateral PANDO were included. Affected eyes were named as group 1 and contralateral eyes as group 2. The Munk score and fluorescein dye disappearance test (FDDT) were assessed. Corneal topographic and HOAs measurements were taken by Sirius topography.Results: There were 47 female and 14 male patients. The mean keratometry was 43.84 \u00b1 1.4 in group 1 and 43.96 \u00b1 1.4 in group 2 (p = 0.73). The mean corneal topographic astigmatism was 0.81 \u00b1 0.7 in group 1 and 0.78 \u00b1 0.5 in group 2 (p = 0.57). The mean coma-like aberration was 0.19 \u00b1 0.2 in group 1 and 0.10 \u00b1 0.1 in group 2 (p = 0.03). The mean spherical-like aberration was 0.16 \u00b1 0.1 in group 1 and 0.11 \u00b1 0.1 in group 2 (p = 0.04). The mean total corneal HOA was 0.30 \u00b1 0.5 in group 1 and 0.23 \u00b1 0.2 in group 2 (p = 0.04). The mean Munk score was 3.47 \u00b1 1.0 in group 1. There was a positive correlation between the Munk score and both coma-like aberration (r = 0.53, p = 0.003) and total corneal HOAs (r = 0.44, p = 0.010). The mean FDDT grade was 2.60 \u00b1 0.1 in group 1. A positive correlation was observed between the FDDT grade and both coma-like aberration (r = 0.48, p = 0.001) and total corneal HOAs (r = 0.33, p = 0.001).Conclusions: Epiphora in patients with PANDO can affect corneal HOAs. 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