{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:30:03Z","timestamp":1790713803916,"version":"4.1.0"},"reference-count":35,"publisher":"XMLink","issue":"4","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0"}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["J Korean Med Sci"],"published-print":{"date-parts":[[2006]]},"DOI":"10.3346\/jkms.2006.21.4.733","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T00:59:51Z","timestamp":1201136391000},"page":"733","update-policy":"https:\/\/doi.org\/10.3346\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Upregulation of Proinflammatory Cytokines in the Fetal Brain of the Gaucher Mouse"],"prefix":"10.3346","volume":"21","author":[{"given":"Young Bin","family":"Hong","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences, National Institute of Health, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, National Institute of Health, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Chul","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, College of Medicine, Ewha Womans University, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","reference":[{"key":"10.3346\/jkms.2006.21.4.733_ref1","first-page":"3635","volume-title":"The Metabolic and Molecular Bases of Inherited Disease","author":"Beutler","year":"2001"},{"key":"10.3346\/jkms.2006.21.4.733_ref2","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1172\/JCI105417","volume":"45","author":"Brady","year":"1966","journal-title":"J Clin Invest"},{"key":"10.3346\/jkms.2006.21.4.733_ref3","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1001\/archneur.1993.00540110088009","volume":"50","author":"Brady","year":"1993","journal-title":"Arch Neurol"},{"key":"10.3346\/jkms.2006.21.4.733_ref4","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s10038-004-0155-2","volume":"49","author":"Hong","year":"2004","journal-title":"J Hum Genet"},{"key":"10.3346\/jkms.2006.21.4.733_ref5","first-page":"205","volume":"10","author":"Barak","year":"1999","journal-title":"Eur Cytokine Netw"},{"key":"10.3346\/jkms.2006.21.4.733_ref6","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1006\/bcmd.1997.0156","volume":"23","author":"Lichtenstein","year":"1997","journal-title":"Blood Cell Mol Dis"},{"key":"10.3346\/jkms.2006.21.4.733_ref7","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1172\/JCI0214530","volume":"109","author":"Mizukami","year":"2002","journal-title":"J Clin Invest"},{"key":"10.3346\/jkms.2006.21.4.733_ref8","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/S0014-4886(03)00345-5","volume":"184","author":"Baudry","year":"2003","journal-title":"Exp Neurol"},{"key":"10.3346\/jkms.2006.21.4.733_ref9","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1093\/brain\/awg089","volume":"126","author":"Jeyakumar","year":"2003","journal-title":"Brain"},{"key":"10.3346\/jkms.2006.21.4.733_ref10","doi-asserted-by":"crossref","first-page":"8425","DOI":"10.1073\/pnas.0400625101","volume":"101","author":"Wu","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.3346\/jkms.2006.21.4.733_ref11","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/357407a0","volume":"357","author":"Tybulewicz","year":"1992","journal-title":"Nature"},{"key":"10.3346\/jkms.2006.21.4.733_ref12","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/emm.2004.58","volume":"36","author":"Min","year":"2004","journal-title":"Exp Mol Med"},{"key":"10.3346\/jkms.2006.21.4.733_ref13","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1023\/A:1005622001239","volume":"23","author":"Pelled","year":"2000","journal-title":"J Inherit Metab Dis"},{"key":"10.3346\/jkms.2006.21.4.733_ref14","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.4049\/jimmunol.141.7.2407","volume":"141","author":"Ding","year":"1988","journal-title":"J Immunol"},{"key":"10.3346\/jkms.2006.21.4.733_ref15","doi-asserted-by":"crossref","first-page":"21673","DOI":"10.1074\/jbc.274.31.21673","volume":"274","author":"Korkotian","year":"1999","journal-title":"J Biol Chem"},{"key":"10.3346\/jkms.2006.21.4.733_ref16","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/S1096-7192(02)00117-8","volume":"76","author":"Orvisky","year":"2002","journal-title":"Mol Genet Metab"},{"key":"10.3346\/jkms.2006.21.4.733_ref17","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1203\/00006450-200008000-00018","volume":"48","author":"Orvisky","year":"2000","journal-title":"Pediatr Res"},{"key":"10.3346\/jkms.2006.21.4.733_ref18","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1042\/bj20030613","volume":"375","author":"Lloyd-Evans","year":"2003","journal-title":"Biochem J"},{"key":"10.3346\/jkms.2006.21.4.733_ref19","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.nbd.2003.08.016","volume":"14","author":"Schueler","year":"2003","journal-title":"Neurobiol Dis"},{"key":"10.3346\/jkms.2006.21.4.733_ref20","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1023\/B:GLYC.0000046272.38480.ef","volume":"21","author":"Raas-Rothschild","year":"2004","journal-title":"Glycoconj J"},{"key":"10.3346\/jkms.2006.21.4.733_ref21","first-page":"388","volume":"106","author":"Shoenfeld","year":"1982","journal-title":"Arch Pathol Lab Med"},{"key":"10.3346\/jkms.2006.21.4.733_ref22","first-page":"576","volume":"16","author":"Kluth","year":"1996","journal-title":"Semin Nephrol"},{"key":"10.3346\/jkms.2006.21.4.733_ref23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1124\/jpet.102.035048","volume":"304","author":"Liu","year":"2003","journal-title":"J Pharmacol Exp Ther"},{"key":"10.3346\/jkms.2006.21.4.733_ref24","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1212\/WNL.38.8.1285","volume":"38","author":"McGeer","year":"1998","journal-title":"Neurology"},{"key":"10.3346\/jkms.2006.21.4.733_ref25","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1097\/00005072-199407000-00002","volume":"53","author":"Raine","year":"1994","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.3346\/jkms.2006.21.4.733_ref26","first-page":"469","volume":"54","author":"Guzik","year":"2003","journal-title":"J Physiol Pharmalcol"},{"key":"10.3346\/jkms.2006.21.4.733_ref27","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1038\/ni1001-907","volume":"2","author":"Bogdan","year":"2001","journal-title":"Nat Immunol"},{"key":"10.3346\/jkms.2006.21.4.733_ref28","first-page":"17","volume":"102","author":"Faber","year":"1994","journal-title":"Environ Health Perspect"},{"key":"10.3346\/jkms.2006.21.4.733_ref29","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1046\/j.1471-4159.2003.02242.x","volume":"88","author":"Wang","year":"2004","journal-title":"J Neurochem"},{"key":"10.3346\/jkms.2006.21.4.733_ref30","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.1046\/j.1523-1755.2002.00367.x","volume":"61","author":"Lal","year":"2002","journal-title":"Kidney Int"},{"key":"10.3346\/jkms.2006.21.4.733_ref31","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1046\/j.1471-4159.2001.00520.x","volume":"79","author":"Rosenberger","year":"2001","journal-title":"J Nerurochem"},{"key":"10.3346\/jkms.2006.21.4.733_ref32","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1093\/hmg\/11.11.1343","volume":"11","author":"Myerowitz","year":"2002","journal-title":"Hum Mol Genet"},{"key":"10.3346\/jkms.2006.21.4.733_ref33","doi-asserted-by":"crossref","first-page":"10954","DOI":"10.1073\/pnas.97.20.10954","volume":"97","author":"Wada","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.3346\/jkms.2006.21.4.733_ref34","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1073\/pnas.95.5.2503","volume":"95","author":"Liu","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.3346\/jkms.2006.21.4.733_ref35","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1016\/S0002-9440(10)63566-3","volume":"163","author":"Xu","year":"2003","journal-title":"Am J Pathol"}],"container-title":["Journal of Korean Medical Science"],"original-title":[],"link":[{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3346\/jkms.2006.21.4.733","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.3346\/jkms.2006.21.4.733","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2006.21.4.733","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T01:57:06Z","timestamp":1684202226000},"score":1,"resource":{"primary":{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2006.21.4.733"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006]]}},"URL":"https:\/\/doi.org\/10.3346\/jkms.2006.21.4.733","relation":{},"ISSN":["1011-8934"],"issn-type":[{"value":"1011-8934","type":"print"}],"subject":[],"published":{"date-parts":[[2006]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3346\/jkms.2006.21.4.733","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3346\/jkms.2006.21.4.733","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"http:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2006.21.4.733","URL":"http:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2006.21.4.733","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2005-11-09","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2005-12-27","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2006-08-22","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2006 The Korean Academy of Medical Sciences","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}