{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:28:01Z","timestamp":1792099681228,"version":"4.4.0"},"reference-count":35,"publisher":"Korean Academy of Medical Sciences","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0"}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["J Korean Med Sci"],"published-print":{"date-parts":[[2009]]},"DOI":"10.3346\/jkms.2009.24.1.77","type":"journal-article","created":{"date-parts":[[2009,3,4]],"date-time":"2009-03-04T07:29:54Z","timestamp":1236151794000},"page":"77","update-policy":"https:\/\/doi.org\/10.3346\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Improved Detection of Germline Mutations in Korean VHL Patients by Multiple Ligation-dependent Probe Amplification Analysis"],"prefix":"10.3346","volume":"24","author":[{"given":"Hyun-Jung","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine, Konyang Univeristy Hospital, College of Medical Science Konyang University, Daejon, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Seok","family":"Ki","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong-Won","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1898","reference":[{"key":"10.3346\/jkms.2009.24.1.77_ref1","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/0002-9343(64)90107-X","volume":"36","author":"Melmon","year":"1964","journal-title":"Am J Med"},{"key":"10.3346\/jkms.2009.24.1.77_ref2","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1148\/radiology.194.3.7862955","volume":"194","author":"Choyke","year":"1995","journal-title":"Radiology"},{"key":"10.3346\/jkms.2009.24.1.77_ref3","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1016\/S0090-4295(97)00074-5","volume":"49","author":"Choyke","year":"1997","journal-title":"Urology"},{"key":"10.3346\/jkms.2009.24.1.77_ref4","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1001\/jama.1997.03540420057030","volume":"277","author":"Manski","year":"1997","journal-title":"JAMA"},{"key":"10.3346\/jkms.2009.24.1.77_ref5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s101430050024","volume":"23","author":"Richard","year":"2000","journal-title":"Neurosurg Rev"},{"key":"10.3346\/jkms.2009.24.1.77_ref6","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1136\/jmg.33.2.120","volume":"33","author":"Maddock","year":"1996","journal-title":"J Med Genet"},{"key":"10.3346\/jkms.2009.24.1.77_ref7","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1136\/jmg.28.7.443","volume":"28","author":"Maher","year":"1991","journal-title":"J Med Genet"},{"key":"10.3346\/jkms.2009.24.1.77_ref8","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/nrc885","volume":"2","author":"Kaelin","year":"2002","journal-title":"Nat Rev Cancer"},{"key":"10.3346\/jkms.2009.24.1.77_ref9","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1038\/332268a0","volume":"332","author":"Seizinger","year":"1998","journal-title":"Nature"},{"key":"10.3346\/jkms.2009.24.1.77_ref10","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1126\/science.8493574","volume":"260","author":"Latif","year":"1993","journal-title":"Science"},{"key":"10.3346\/jkms.2009.24.1.77_ref11","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1093\/hmg\/3.8.1303","volume":"3","author":"Crossey","year":"1994","journal-title":"Hum Mol Genet"},{"key":"10.3346\/jkms.2009.24.1.77_ref12","first-page":"1092","volume":"55","author":"Whaley","year":"1994","journal-title":"Am J Hum Genet"},{"key":"10.3346\/jkms.2009.24.1.77_ref13","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/humu.1380050109","volume":"5","author":"Chen","year":"1995","journal-title":"Hum Mutat"},{"key":"10.3346\/jkms.2009.24.1.77_ref14","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1093\/hmg\/4.12.2233","volume":"4","author":"Clinical Research Group for VHL in Japan","year":"1995","journal-title":"Hum Mol Genet"},{"key":"10.3346\/jkms.2009.24.1.77_ref15","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1136\/jmg.33.4.328","volume":"33","author":"Maher","year":"1996","journal-title":"J Med Genet"},{"key":"10.3346\/jkms.2009.24.1.77_ref16","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1002\/(SICI)1098-1004(1996)8:4<348::AID-HUMU8>3.0.CO;2-3","volume":"8","author":"Zbar","year":"1996","journal-title":"Hum Mutat"},{"key":"10.3346\/jkms.2009.24.1.77_ref17","first-page":"4184","volume":"61","author":"Kamada","year":"2001","journal-title":"Cancer Res"},{"key":"10.3346\/jkms.2009.24.1.77_ref18","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1002\/(SICI)1098-1004(1998)12:6<417::AID-HUMU8>3.0.CO;2-K","volume":"12","author":"Stolle","year":"1998","journal-title":"Hum Mutat"},{"key":"10.3346\/jkms.2009.24.1.77_ref19","doi-asserted-by":"crossref","first-page":"e31","DOI":"10.1136\/jmg.40.3.e31","volume":"40","author":"Rocha","year":"2003","journal-title":"J Med Genet"},{"key":"10.3346\/jkms.2009.24.1.77_ref20","doi-asserted-by":"crossref","first-page":"e57","DOI":"10.1093\/nar\/gnf056","volume":"30","author":"Schouten","year":"2002","journal-title":"Nucleic Acids Res"},{"key":"10.3346\/jkms.2009.24.1.77_ref21","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1002\/humu.20035","volume":"23","author":"Sellner","year":"2004","journal-title":"Hum Mutat"},{"key":"10.3346\/jkms.2009.24.1.77_ref22","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s10048-006-0051-3","volume":"7","author":"Scarciolla","year":"2006","journal-title":"Neurogenetics"},{"key":"10.3346\/jkms.2009.24.1.77_ref23","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s004399900137","volume":"105","author":"Cybulski","year":"1999","journal-title":"Hum Genet"},{"key":"10.3346\/jkms.2009.24.1.77_ref24","doi-asserted-by":"crossref","first-page":"E38","DOI":"10.1136\/jmg.39.7.e38","volume":"39","author":"Cybulski","year":"2002","journal-title":"J Med Genet"},{"key":"10.3346\/jkms.2009.24.1.77_ref25","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1086\/302726","volume":"66","author":"Sgambati","year":"2000","journal-title":"Am J Hum Genet"},{"key":"10.3346\/jkms.2009.24.1.77_ref26","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s004390050206","volume":"98","author":"Glavac","year":"1996","journal-title":"Hum Genet"},{"key":"10.3346\/jkms.2009.24.1.77_ref27","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1093\/qjmed\/77.2.1151","volume":"77","author":"Maher","year":"1990","journal-title":"Q J Med"},{"key":"10.3346\/jkms.2009.24.1.77_ref28","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1046\/j.1365-2796.1998.00337.x","volume":"243","author":"Richard","year":"1998","journal-title":"J Intern Med"},{"key":"10.3346\/jkms.2009.24.1.77_ref29","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1002\/(SICI)1098-1004(1999)13:6<464::AID-HUMU6>3.0.CO;2-A","volume":"13","author":"Gallou","year":"1999","journal-title":"Hum Mutat"},{"key":"10.3346\/jkms.2009.24.1.77_ref30","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/humu.20082","volume":"24","author":"Gallou","year":"2004","journal-title":"Hum Mutat"},{"key":"10.3346\/jkms.2009.24.1.77_ref31","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/j.1349-7006.2000.tb00933.x","volume":"91","author":"Yoshida","year":"2000","journal-title":"Jpn J Cancer Res"},{"key":"10.3346\/jkms.2009.24.1.77_ref32","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1093\/hmg\/10.7.763","volume":"10","author":"Friedrich","year":"2001","journal-title":"Hum Mol Genet"},{"key":"10.3346\/jkms.2009.24.1.77_ref33","first-page":"879","volume":"14","author":"Kang","year":"2005","journal-title":"Oncol Rep"},{"key":"10.3346\/jkms.2009.24.1.77_ref34","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1002\/(SICI)1098-1004(1998)12:6<424::AID-HUMU9>3.0.CO;2-H","volume":"12","author":"Olschwang","year":"1998","journal-title":"Hum Mutat"},{"key":"10.3346\/jkms.2009.24.1.77_ref35","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1136\/jmg.32.11.885","volume":"32","author":"Crossey","year":"1995","journal-title":"J Med Genet"}],"container-title":["Journal of Korean Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3346\/jkms.2009.24.1.77","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.3346\/jkms.2009.24.1.77","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2009.24.1.77","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T05:51:00Z","timestamp":1589521860000},"score":1,"resource":{"primary":{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2009.24.1.77"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.3346\/jkms.2009.24.1.77","relation":{},"ISSN":["1011-8934"],"issn-type":[{"value":"1011-8934","type":"print"}],"subject":[],"published":{"date-parts":[[2009]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3346\/jkms.2009.24.1.77","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3346\/jkms.2009.24.1.77","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"http:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2009.24.1.77","URL":"http:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2009.24.1.77","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2008-03-25","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-05-28","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-02-28","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2009 The Korean Academy of Medical Sciences","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}