{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T23:16:18Z","timestamp":1782774978493,"version":"3.54.5"},"reference-count":29,"publisher":"Korean Academy of Medical Sciences","issue":"3","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0"}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["J Korean Med Sci"],"published-print":{"date-parts":[[2012]]},"DOI":"10.3346\/jkms.2012.27.3.268","type":"journal-article","created":{"date-parts":[[2012,2,25]],"date-time":"2012-02-25T01:19:15Z","timestamp":1330132755000},"page":"268","update-policy":"https:\/\/doi.org\/10.3346\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Spontaneously Reported Hepatic Adverse Drug Events in Korea: Multicenter Study"],"prefix":"10.3346","volume":"27","author":[{"given":"Hee","family":"Kwon","sequence":"first","affiliation":[{"name":"Severance Regional Pharmacovigilance Center, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suk-Hyang","family":"Lee","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Ajou University, Suwon, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong-Eun","family":"Kim","sequence":"additional","affiliation":[{"name":"Severance Regional Pharmacovigilance Center, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Hyun","family":"Lee","sequence":"additional","affiliation":[{"name":"Severance Regional Pharmacovigilance Center, Seoul, Korea."},{"name":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yung-Koo","family":"Jee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hye-Ryun","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung-Joo","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung-Won","family":"Park","sequence":"additional","affiliation":[{"name":"Severance Regional Pharmacovigilance Center, Seoul, Korea."},{"name":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chein-Soo","family":"Hong","sequence":"additional","affiliation":[{"name":"Severance Regional Pharmacovigilance Center, Seoul, Korea."},{"name":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1898","reference":[{"key":"10.3346\/jkms.2012.27.3.268_ref1","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1002\/lt.20204","volume":"10","author":"Russo","year":"2004","journal-title":"Liver Transpl"},{"key":"10.3346\/jkms.2012.27.3.268_ref2","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1055\/s-2002-30105","volume":"22","author":"Larrey","year":"2002","journal-title":"Semin Liver Dis"},{"key":"10.3346\/jkms.2012.27.3.268_ref3","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1056\/NEJMra052270","volume":"354","author":"Navarro","year":"2006","journal-title":"N Engl J Med"},{"key":"10.3346\/jkms.2012.27.3.268_ref4","first-page":"8","volume":"35","author":"Meadows","year":"2001","journal-title":"FDA Consum"},{"key":"10.3346\/jkms.2012.27.3.268_ref5","doi-asserted-by":"crossref","first-page":"483","DOI":"10.3350\/kjhep.2008.14.4.483","volume":"14","author":"Kang","year":"2008","journal-title":"Korean J Hepatol"},{"key":"10.3346\/jkms.2012.27.3.268_ref6","first-page":"125","volume":"10","author":"Kim","year":"2004","journal-title":"Korean J Hepatol"},{"key":"10.3346\/jkms.2012.27.3.268_ref7","first-page":"74","volume":"12","author":"Seo","year":"2006","journal-title":"Korean J Hepatol"},{"key":"10.3346\/jkms.2012.27.3.268_ref8","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1111\/j.1478-3231.2007.01461.x","volume":"27","author":"Wai","year":"2007","journal-title":"Liver Int"},{"key":"10.3346\/jkms.2012.27.3.268_ref9","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.gastro.2005.05.006","volume":"129","author":"Andrade","year":"2005","journal-title":"Gastroenterology"},{"key":"10.3346\/jkms.2012.27.3.268_ref10","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1053\/j.gastro.2008.09.011","volume":"135","author":"Chalasani","year":"2008","journal-title":"Gastroenterology"},{"key":"10.3346\/jkms.2012.27.3.268_ref11","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1002\/pds.1796","volume":"18","author":"Shin","year":"2009","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.3346\/jkms.2012.27.3.268_ref12","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1046\/j.1365-2125.1997.05417.x","volume":"43","author":"Moride","year":"1997","journal-title":"Br J Clin Pharmacol"},{"key":"10.3346\/jkms.2012.27.3.268_ref13","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1111\/j.1365-2125.2005.02504.x","volume":"60","author":"Vallano","year":"2005","journal-title":"Br J Clin Pharmacol"},{"key":"10.3346\/jkms.2012.27.3.268_ref14","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/pds.668","volume":"11","author":"van Puijenbroek","year":"2002","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.3346\/jkms.2012.27.3.268_ref15","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1002\/pds.1001","volume":"13","author":"Rothman","year":"2004","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.3346\/jkms.2012.27.3.268_ref16","volume-title":"The WHO-ART Adverse Reaction Terminology","author":"The Uppsala Monitoring Centre","year":"2005"},{"key":"10.3346\/jkms.2012.27.3.268_ref17","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/S0140-6736(00)02799-9","volume":"356","author":"Edwards","year":"2000","journal-title":"Lancet"},{"key":"10.3346\/jkms.2012.27.3.268_ref18","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/pds.1947","volume":"20","author":"Shin","year":"2011","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.3346\/jkms.2012.27.3.268_ref19","volume-title":"Safety monitoring of medicinal products: Guidelines for setting up and running a pharmacovigilance centre","author":"WHO and the Uppsala Monitoring Centre","year":"2000"},{"key":"10.3346\/jkms.2012.27.3.268_ref20","doi-asserted-by":"crossref","first-page":"999","DOI":"10.5124\/jkma.2010.53.11.999","volume":"53","author":"Song","year":"2010","journal-title":"J Korean Med Assoc"},{"key":"10.3346\/jkms.2012.27.3.268_ref21","doi-asserted-by":"crossref","first-page":"947","DOI":"10.7326\/0003-4819-137-12-200212170-00007","volume":"137","author":"Ostapowicz","year":"2002","journal-title":"Ann Intern Med"},{"key":"10.3346\/jkms.2012.27.3.268_ref22","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1136\/bmj.319.7224.1541","volume":"319","author":"Aithal","year":"1999","journal-title":"BMJ"},{"key":"10.3346\/jkms.2012.27.3.268_ref23","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.cgh.2010.02.008","volume":"8","author":"Agarwal","year":"2010","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.3346\/jkms.2012.27.3.268_ref24","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/0895-4356(93)90101-6","volume":"46","author":"Danan","year":"1993","journal-title":"J Clin Epidemiol"},{"key":"10.3346\/jkms.2012.27.3.268_ref25","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/0895-4356(93)90102-7","volume":"46","author":"Benichou","year":"1993","journal-title":"J Clin Epidemiol"},{"key":"10.3346\/jkms.2012.27.3.268_ref26","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1002\/hep.22442","volume":"48","author":"Rochon","year":"2008","journal-title":"Hepatology"},{"key":"10.3346\/jkms.2012.27.3.268_ref27","first-page":"1381","volume":"99","author":"Akhtar","year":"2007","journal-title":"J Natl Med Assoc"},{"key":"10.3346\/jkms.2012.27.3.268_ref28","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1164\/ajrccm.157.6.9711039","volume":"157","author":"Ungo","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"key":"10.3346\/jkms.2012.27.3.268_ref29","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.cld.2007.06.003","volume":"11","author":"Shapiro","year":"2007","journal-title":"Clin Liver Dis"}],"container-title":["Journal of Korean Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.3346\/jkms.2012.27.3.268","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3346\/jkms.2012.27.3.268","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2012.27.3.268","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T06:05:21Z","timestamp":1589522721000},"score":1,"resource":{"primary":{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2012.27.3.268"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.3346\/jkms.2012.27.3.268","relation":{},"ISSN":["1011-8934","1598-6357"],"issn-type":[{"value":"1011-8934","type":"print"},{"value":"1598-6357","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3346\/jkms.2012.27.3.268","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3346\/jkms.2012.27.3.268","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"http:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2012.27.3.268","URL":"http:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2012.27.3.268","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2011-07-23","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-12-26","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-02-23","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2012 The Korean Academy of Medical Sciences.","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}