{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:45:45Z","timestamp":1753890345057,"version":"3.41.2"},"reference-count":24,"publisher":"XMLink","issue":"15","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["J Korean Med Sci"],"DOI":"10.3346\/jkms.2018.33.e123","type":"journal-article","created":{"date-parts":[[2018,4,8]],"date-time":"2018-04-08T23:16:26Z","timestamp":1523229386000},"update-policy":"https:\/\/doi.org\/10.3346\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Anaplastic lymphoma kinase (ALK)-expressing Lung Adenocarcinoma with Combined Neuroendocrine Component or Neuroendocrine Transformation: Implications for Neuroendocrine Transformation and Response to ALK-tyrosine Kinase Inhibitors"],"prefix":"10.3346","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7106-1279","authenticated-orcid":false,"given":"Jongmin","family":"Sim","sequence":"first","affiliation":[{"name":"Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8336-881X","authenticated-orcid":false,"given":"Hyunjin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3074-4142","authenticated-orcid":false,"given":"Jiyeon","family":"Hyeon","sequence":"additional","affiliation":[{"name":"Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5788-5140","authenticated-orcid":false,"given":"Yoon-La","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4424-7008","authenticated-orcid":false,"given":"Joungho","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18617","published-online":{"date-parts":[[2018]]},"reference":[{"issue":"1","key":"10.3346\/jkms.2018.33.e123_ref1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3322\/caac.21387","volume":"67","author":"Siegel","year":"2017","journal-title":"CA Cancer J Clin"},{"issue":"2","key":"10.3346\/jkms.2018.33.e123_ref2","doi-asserted-by":"crossref","first-page":"292","DOI":"10.4143\/crt.2017.118","volume":"49","author":"Jung","year":"2017","journal-title":"Cancer Res Treat"},{"issue":"9","key":"10.3346\/jkms.2018.33.e123_ref3","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1097\/JTO.0000000000000630","volume":"10","author":"Travis","year":"2015","journal-title":"J Thorac Oncol"},{"issue":"5","key":"10.3346\/jkms.2018.33.e123_ref4","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1097\/PAP.0000000000000121","volume":"23","author":"Kim","year":"2016","journal-title":"Adv Anat Pathol"},{"issue":"2","key":"10.3346\/jkms.2018.33.e123_ref5","doi-asserted-by":"crossref","first-page":"763","DOI":"10.3390\/cancers7020763","volume":"7","author":"Isozaki","year":"2015","journal-title":"Cancers (Basel)"},{"issue":"10","key":"10.3346\/jkms.2018.33.e123_ref6","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1158\/1078-0432.CCR-07-2248","volume":"14","author":"Engelman","year":"2008","journal-title":"Clin Cancer Res"},{"issue":"75","key":"10.3346\/jkms.2018.33.e123_ref7","doi-asserted-by":"crossref","first-page":"75ra26","DOI":"10.1126\/scitranslmed.3002003","volume":"3","author":"Sequist","year":"2011","journal-title":"Sci Transl Med"},{"issue":"8","key":"10.3346\/jkms.2018.33.e123_ref8","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1158\/1078-0432.CCR-12-2246","volume":"19","author":"Yu","year":"2013","journal-title":"Clin Cancer Res"},{"issue":"4","key":"10.3346\/jkms.2018.33.e123_ref9","doi-asserted-by":"crossref","first-page":"e165","DOI":"10.1016\/S1470-2045(14)71180-5","volume":"16","author":"Oser","year":"2015","journal-title":"Lancet Oncol"},{"key":"10.3346\/jkms.2018.33.e123_ref10","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.lungcan.2016.10.012","volume":"102","author":"Levacq","year":"2016","journal-title":"Lung Cancer"},{"issue":"4","key":"10.3346\/jkms.2018.33.e123_ref11","doi-asserted-by":"crossref","first-page":"258","DOI":"10.4132\/jptm.2016.04.19","volume":"50","author":"Ahn","year":"2016","journal-title":"J Pathol Transl Med"},{"issue":"1","key":"10.3346\/jkms.2018.33.e123_ref12","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jtho.2015.09.013","volume":"11","author":"Ham","year":"2016","journal-title":"J Thorac Oncol"},{"key":"10.3346\/jkms.2018.33.e123_ref13","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1186\/s12885-016-2623-4","volume":"16","author":"Lin","year":"2016","journal-title":"BMC Cancer"},{"issue":"5","key":"10.3346\/jkms.2018.33.e123_ref14","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1093\/annonc\/mdw032","volume":"27","author":"Takegawa","year":"2016","journal-title":"Ann Oncol"},{"issue":"3","key":"10.3346\/jkms.2018.33.e123_ref15","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.lungcan.2015.10.002","volume":"90","author":"Shen","year":"2015","journal-title":"Lung Cancer"},{"issue":"2","key":"10.3346\/jkms.2018.33.e123_ref16","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.lungcan.2015.05.012","volume":"89","author":"Savic","year":"2015","journal-title":"Lung Cancer"},{"issue":"5","key":"10.3346\/jkms.2018.33.e123_ref17","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1097\/PAS.0000000000000604","volume":"40","author":"Jiang","year":"2016","journal-title":"Am J Surg Pathol"},{"issue":"12","key":"10.3346\/jkms.2018.33.e123_ref18","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1038\/modpathol.2013.87","volume":"26","author":"Selinger","year":"2013","journal-title":"Mod Pathol"},{"issue":"8","key":"10.3346\/jkms.2018.33.e123_ref19","doi-asserted-by":"crossref","first-page":"e75","DOI":"10.1097\/JTO.0b013e318293d96f","volume":"8","author":"Kobayashi","year":"2013","journal-title":"J Thorac Oncol"},{"issue":"2","key":"10.3346\/jkms.2018.33.e123_ref20","first-page":"170","volume":"46","author":"Miyamoto","year":"2016","journal-title":"Jpn J Clin Oncol"},{"issue":"5","key":"10.3346\/jkms.2018.33.e123_ref21","doi-asserted-by":"crossref","first-page":"e55","DOI":"10.1016\/j.jtho.2015.12.097","volume":"11","author":"Cha","year":"2016","journal-title":"J Thorac Oncol"},{"key":"10.3346\/jkms.2018.33.e123_ref22","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.lungcan.2015.12.001","volume":"92","author":"Caumont","year":"2016","journal-title":"Lung Cancer"},{"issue":"6","key":"10.3346\/jkms.2018.33.e123_ref23","doi-asserted-by":"crossref","first-page":"e67","DOI":"10.1016\/j.jtho.2015.12.105","volume":"11","author":"Fujita","year":"2016","journal-title":"J Thorac Oncol"},{"key":"10.3346\/jkms.2018.33.e123_ref24","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.lungcan.2017.01.005","volume":"105","author":"Le","year":"2017","journal-title":"Lung Cancer"}],"container-title":["Journal of Korean Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jkms.org\/pdf\/10.3346\/jkms.2018.33.e123","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2018.33.e123","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2018.33.e123","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T06:37:47Z","timestamp":1589524667000},"score":1,"resource":{"primary":{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2018.33.e123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":24,"journal-issue":{"issue":"15","published-online":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.3346\/jkms.2018.33.e123","relation":{},"ISSN":["1011-8934","1598-6357"],"issn-type":[{"type":"print","value":"1011-8934"},{"type":"electronic","value":"1598-6357"}],"subject":[],"published":{"date-parts":[[2018]]},"assertion":[{"value":"2017-09-05","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-01-19","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-04-03","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2018 The Korean Academy of Medical Sciences.","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}],"article-number":"e123"}}