{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T16:35:01Z","timestamp":1790440501433,"version":"4.1.0"},"reference-count":54,"publisher":"XMLink","issue":"28","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2014R1A1A1005144"],"award-info":[{"award-number":["NRF-2014R1A1A1005144"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2021M3E5D1A01015177"],"award-info":[{"award-number":["NRF-2021M3E5D1A01015177"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jkms.org"],"crossmark-restriction":false},"short-container-title":["J Korean Med Sci"],"DOI":"10.3346\/jkms.2021.36.e189","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T00:09:11Z","timestamp":1625443751000},"update-policy":"https:\/\/doi.org\/10.3346\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Association of Microbial Dysbiosis with Gallbladder Diseases Identified by Bile Microbiome Profiling"],"prefix":"10.3346","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1969-516X","authenticated-orcid":false,"given":"Seong Ji","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8273-884X","authenticated-orcid":false,"given":"Yeseul","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hanyang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4684-0745","authenticated-orcid":false,"given":"Jehyun","family":"Jeon","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Engineering, College of Engineering, Hanyang University, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7765-0827","authenticated-orcid":false,"given":"Ho-Jin","family":"Gwak","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Engineering, College of Engineering, Hanyang University, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8266-0226","authenticated-orcid":false,"given":"Mimi","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hanyang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0993-6967","authenticated-orcid":false,"given":"Kyojin","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hanyang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0212-1688","authenticated-orcid":false,"given":"Yohan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hanyang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9758-7917","authenticated-orcid":false,"given":"Jaemin","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hanyang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5193-5418","authenticated-orcid":false,"given":"Yun Kyung","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hanyang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3275-3544","authenticated-orcid":false,"given":"Kyeong Geun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hanyang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3746-8742","authenticated-orcid":false,"given":"Ho Soon","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5984-023X","authenticated-orcid":false,"given":"Dong-Hwan","family":"Jung","sequence":"additional","affiliation":[{"name":"Division of Liver Transplantation and Hepatobiliary Surgery, Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9161-3491","authenticated-orcid":false,"given":"Sung-Gyu","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Liver Transplantation and Hepatobiliary Surgery, Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3821-3741","authenticated-orcid":false,"given":"Yangsoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Hanyang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9114-8438","authenticated-orcid":false,"given":"Su-Jin","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hanyang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6585-3990","authenticated-orcid":false,"given":"Kiseok","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hanyang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1638-5921","authenticated-orcid":false,"given":"Mina","family":"Rho","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Engineering, College of Engineering, Hanyang University, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1255-1964","authenticated-orcid":false,"given":"Dongho","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hanyang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","published-online":{"date-parts":[[2021]]},"reference":[{"key":"10.3346\/jkms.2021.36.e189_ref1","unstructured":"Global cancer observatory: cancer today. Updated 2020. Accessed March 20, 2020. https:\/\/gco.iarc.fr\/today"},{"issue":"2","key":"10.3346\/jkms.2021.36.e189_ref2","first-page":"200","volume":"84","author":"Yamaguchi","year":"1997","journal-title":"Br J Surg"},{"issue":"4","key":"10.3346\/jkms.2021.36.e189_ref3","doi-asserted-by":"crossref","first-page":"e183","DOI":"10.1016\/j.suronc.2012.08.002","volume":"21","author":"Boutros","year":"2012","journal-title":"Surg Oncol"},{"issue":"43","key":"10.3346\/jkms.2021.36.e189_ref4","doi-asserted-by":"crossref","first-page":"5395","DOI":"10.3748\/wjg.v16.i43.5395","volume":"16","author":"Nath","year":"2010","journal-title":"World J Gastroenterol"},{"issue":"6","key":"10.3346\/jkms.2021.36.e189_ref5","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1097\/00008469-199712000-00011","volume":"6","author":"Nath","year":"1997","journal-title":"Eur J Cancer Prev"},{"issue":"1","key":"10.3346\/jkms.2021.36.e189_ref6","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1038\/sj.bjc.6604780","volume":"100","author":"de Martel","year":"2009","journal-title":"Br J Cancer"},{"issue":"6","key":"10.3346\/jkms.2021.36.e189_ref7","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.chom.2015.05.002","volume":"17","author":"Scanu","year":"2015","journal-title":"Cell Host Microbe"},{"issue":"12","key":"10.3346\/jkms.2021.36.e189_ref8","doi-asserted-by":"crossref","first-page":"e84058","DOI":"10.1371\/journal.pone.0084058","volume":"8","author":"Gonzalez-Escobedo","year":"2013","journal-title":"PLoS One"},{"issue":"6","key":"10.3346\/jkms.2021.36.e189_ref9","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1053\/j.gastro.2014.01.001","volume":"146","author":"Abreu","year":"2014","journal-title":"Gastroenterology"},{"issue":"3","key":"10.3346\/jkms.2021.36.e189_ref10","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1080\/00365521.1976.12097105","volume":"11","author":"Lykkegaard Nielsen","year":"1976","journal-title":"Scand J Gastroenterol"},{"issue":"15","key":"10.3346\/jkms.2021.36.e189_ref11","doi-asserted-by":"crossref","first-page":"e94","DOI":"10.3346\/jkms.2021.36.e94","volume":"36","author":"Kim","year":"2021","journal-title":"J Korean Med Sci"},{"issue":"4","key":"10.3346\/jkms.2021.36.e189_ref12","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.femsre.2004.09.003","volume":"29","author":"Begley","year":"2005","journal-title":"FEMS Microbiol Rev"},{"issue":"1","key":"10.3346\/jkms.2021.36.e189_ref13","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/s40168-019-0712-8","volume":"7","author":"Molinero","year":"2019","journal-title":"Microbiome"},{"issue":"5","key":"10.3346\/jkms.2021.36.e189_ref14","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.2214\/AJR.07.3599","volume":"191","author":"Furlan","year":"2008","journal-title":"AJR Am J Roentgenol"},{"issue":"3","key":"10.3346\/jkms.2021.36.e189_ref15","doi-asserted-by":"crossref","first-page":"765","DOI":"10.2214\/AJR.07.3331","volume":"191","author":"Kim","year":"2008","journal-title":"AJR Am J Roentgenol"},{"issue":"1","key":"10.3346\/jkms.2021.36.e189_ref16","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/s00261-003-0080-4","volume":"29","author":"Yun","year":"2004","journal-title":"Abdom Imaging"},{"issue":"3","key":"10.3346\/jkms.2021.36.e189_ref17","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S1092-9134(03)00011-X","volume":"7","author":"Barcia","year":"2003","journal-title":"Ann Diagn Pathol"},{"issue":"21","key":"10.3346\/jkms.2021.36.e189_ref18","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1093\/bioinformatics\/btr507","volume":"27","author":"Mago\\xc4\\x8d","year":"2011","journal-title":"Bioinformatics"},{"issue":"23","key":"10.3346\/jkms.2021.36.e189_ref19","doi-asserted-by":"crossref","first-page":"3150","DOI":"10.1093\/bioinformatics\/bts565","volume":"28","author":"Fu","year":"2012","journal-title":"Bioinformatics"},{"issue":"16","key":"10.3346\/jkms.2021.36.e189_ref20","doi-asserted-by":"crossref","first-page":"5261","DOI":"10.1128\/AEM.00062-07","volume":"73","author":"Wang","year":"2007","journal-title":"Appl Environ Microbiol"},{"issue":"1","key":"10.3346\/jkms.2021.36.e189_ref21","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/s12915-014-0087-z","volume":"12","author":"Salter","year":"2014","journal-title":"BMC Biol"},{"issue":"4","key":"10.3346\/jkms.2021.36.e189_ref22","doi-asserted-by":"crossref","first-page":"e00290-19","DOI":"10.1128\/mSystems.00290-19","volume":"4","author":"Karstens","year":"2019","journal-title":"mSystems"},{"issue":"10","key":"10.3346\/jkms.2021.36.e189_ref23","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1093\/bioinformatics\/btv033","volume":"31","author":"Li","year":"2015","journal-title":"Bioinformatics"},{"issue":"20","key":"10.3346\/jkms.2021.36.e189_ref24","doi-asserted-by":"crossref","first-page":"e191","DOI":"10.1093\/nar\/gkq747","volume":"38","author":"Rho","year":"2010","journal-title":"Nucleic Acids Res"},{"issue":"4","key":"10.3346\/jkms.2021.36.e189_ref25","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.1923","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat Methods"},{"issue":"12","key":"10.3346\/jkms.2021.36.e189_ref26","doi-asserted-by":"crossref","first-page":"e121","DOI":"10.1093\/nar\/gkt263","volume":"41","author":"Mistry","year":"2013","journal-title":"Nucleic Acids Res"},{"issue":"5","key":"10.3346\/jkms.2021.36.e189_ref27","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1093\/nar\/gkh340","volume":"32","author":"Edgar","year":"2004","journal-title":"Nucleic Acids Res"},{"issue":"12","key":"10.3346\/jkms.2021.36.e189_ref28","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1093\/molbev\/mst197","volume":"30","author":"Tamura","year":"2013","journal-title":"Mol Biol Evol"},{"issue":"6","key":"10.3346\/jkms.2021.36.e189_ref29","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1002\/mbo3.218","volume":"3","author":"Jim\u00e9nez","year":"2014","journal-title":"MicrobiologyOpen"},{"key":"10.3346\/jkms.2021.36.e189_ref30","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/978-3-642-38922-1_167","volume-title":"The Prokaryotes: Gammaproteobacteria","author":"Octavia","year":"2014"},{"issue":"9","key":"10.3346\/jkms.2021.36.e189_ref31","doi-asserted-by":"crossref","first-page":"e105046","DOI":"10.1371\/journal.pone.0105046","volume":"9","author":"Brower-Sinning","year":"2014","journal-title":"PLoS One"},{"issue":"1","key":"10.3346\/jkms.2021.36.e189_ref32","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s10096-008-0598-z","volume":"28","author":"Samonis","year":"2009","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"10","key":"10.3346\/jkms.2021.36.e189_ref33","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1001\/archinte.1985.00360100068010","volume":"145","author":"Drelichman","year":"1985","journal-title":"Arch Intern Med"},{"issue":"1","key":"10.3346\/jkms.2021.36.e189_ref34","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1080\/00365520410009546","volume":"40","author":"Apostolov","year":"2005","journal-title":"Scand J Gastroenterol"},{"issue":"4","key":"10.3346\/jkms.2021.36.e189_ref35","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/S0016-5085(98)70589-X","volume":"114","author":"Fox","year":"1998","journal-title":"Gastroenterology"},{"issue":"3","key":"10.3346\/jkms.2021.36.e189_ref36","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1111\/j.1572-0241.2000.01860.x","volume":"95","author":"Dutta","year":"2000","journal-title":"Am J Gastroenterol"},{"issue":"4","key":"10.3346\/jkms.2021.36.e189_ref37","first-page":"961","volume":"19","author":"Tsuchiya","year":"2018","journal-title":"Asian Pac J Cancer Prev"},{"issue":"8","key":"10.3346\/jkms.2021.36.e189_ref38","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1002\/jso.20530","volume":"93","author":"Kumar","year":"2006","journal-title":"J Surg Oncol"},{"issue":"2","key":"10.3346\/jkms.2021.36.e189_ref39","first-page":"32","volume":"110","author":"O\u2019Brien","year":"2014","journal-title":"W V Med J"},{"issue":"3","key":"10.3346\/jkms.2021.36.e189_ref40","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1590\/S0004-28032016000300007","volume":"53","author":"Alves","year":"2016","journal-title":"Arq Gastroenterol"},{"issue":"11","key":"10.3346\/jkms.2021.36.e189_ref41","doi-asserted-by":"crossref","first-page":"3042","DOI":"10.1128\/jcm.33.11.3042-3043.1995","volume":"33","author":"Bottone","year":"1995","journal-title":"J Clin Microbiol"},{"issue":"2","key":"10.3346\/jkms.2021.36.e189_ref42","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1080\/003655499750006344","volume":"31","author":"Alvarez","year":"1999","journal-title":"Scand J Infect Dis"},{"issue":"1","key":"10.3346\/jkms.2021.36.e189_ref43","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1080\/13651820310025192","volume":"6","author":"Hazrah","year":"2004","journal-title":"HPB (Oxford)"},{"issue":"6-7","key":"10.3346\/jkms.2021.36.e189_ref44","first-page":"363","volume":"160","author":"Csendes","year":"1994","journal-title":"Eur J Surg"},{"issue":"986","key":"10.3346\/jkms.2021.36.e189_ref45","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1136\/pgmj.2007.064683","volume":"83","author":"Melzer","year":"2007","journal-title":"Postgrad Med J"},{"issue":"6","key":"10.3346\/jkms.2021.36.e189_ref46","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1086\/513637","volume":"24","author":"Lin","year":"1997","journal-title":"Clin Infect Dis"},{"issue":"9","key":"10.3346\/jkms.2021.36.e189_ref47","doi-asserted-by":"crossref","first-page":"6","DOI":"10.18203\/2320-6012.ijrms20173977","volume":"5","author":"Katyal","year":"2017","journal-title":"Int J Res Med Sci"},{"issue":"1","key":"10.3346\/jkms.2021.36.e189_ref48","doi-asserted-by":"crossref","first-page":"12321","DOI":"10.1038\/s41598-018-30569-5","volume":"8","author":"P\u00f6tgens","year":"2018","journal-title":"Sci Rep"},{"issue":"27","key":"10.3346\/jkms.2021.36.e189_ref49","first-page":"1540","volume":"46","author":"Roa","year":"1999","journal-title":"Hepatogastroenterology"},{"issue":"17","key":"10.3346\/jkms.2021.36.e189_ref50","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1001\/jama.1983.03340170049027","volume":"250","author":"Diehl","year":"1983","journal-title":"JAMA"},{"issue":"10","key":"10.3346\/jkms.2021.36.e189_ref51","first-page":"737","volume":"4","author":"Shaffer","year":"2008","journal-title":"Gastroenterol Hepatol (N Y)"},{"key":"10.3346\/jkms.2021.36.e189_ref52","first-page":"99","volume":"6","author":"Hundal","year":"2014","journal-title":"Clin Epidemiol"},{"issue":"4","key":"10.3346\/jkms.2021.36.e189_ref53","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/j.1440-1827.2005.01816.x","volume":"55","author":"Zen","year":"2005","journal-title":"Pathol Int"},{"issue":"1","key":"10.3346\/jkms.2021.36.e189_ref54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15279\/kpba.2018.23.1.1","volume":"23","author":"Lee","year":"2018","journal-title":"Korean J Pancreas Biliary Tract"}],"container-title":["Journal of Korean Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jkms.org\/pdf\/10.3346\/jkms.2021.36.e189","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2021.36.e189","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2021.36.e189","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T08:48:27Z","timestamp":1725353307000},"score":1,"resource":{"primary":{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2021.36.e189"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":54,"journal-issue":{"issue":"28","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.3346\/jkms.2021.36.e189","relation":{},"ISSN":["1011-8934","1598-6357"],"issn-type":[{"value":"1011-8934","type":"print"},{"value":"1598-6357","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"2021-04-18","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-28","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2021 The Korean Academy of Medical Sciences.","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}],"article-number":"e189"}}