{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T03:48:44Z","timestamp":1790135324842,"version":"4.0.1"},"reference-count":9,"publisher":"XMLink","issue":"28","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2017M3A9F3047495"],"award-info":[{"award-number":["NRF-2017M3A9F3047495"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jkms.org"],"crossmark-restriction":false},"short-container-title":["J Korean Med Sci"],"DOI":"10.3346\/jkms.2022.37.e220","type":"journal-article","created":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T01:15:40Z","timestamp":1656983740000},"update-policy":"https:\/\/doi.org\/10.3346\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Establishment of Patient-Derived Gastric Cancer Organoid Model From Tissue Obtained by Endoscopic Biopsies"],"prefix":"10.3346","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9869-2409","authenticated-orcid":false,"given":"Hana","family":"Song","sequence":"first","affiliation":[{"name":"Laboratory of Gastrointestinal Mucosal Immunology, Chung-Ang University College of Medicine, Seoul, Korea."},{"name":"Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6114-8920","authenticated-orcid":false,"given":"Jae Yong","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5620-6564","authenticated-orcid":false,"given":"Ju-Hee","family":"Kim","sequence":"additional","affiliation":[{"name":"Laboratory of Gastrointestinal Mucosal Immunology, Chung-Ang University College of Medicine, Seoul, Korea."},{"name":"Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8165-0595","authenticated-orcid":false,"given":"Tae-Seop","family":"Shin","sequence":"additional","affiliation":[{"name":"Institute of MD Healthcare Inc., Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7902-4608","authenticated-orcid":false,"given":"Soon Auck","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Pathology, Chung-Ang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1653-7470","authenticated-orcid":false,"given":"Md Nazmul","family":"Huda","sequence":"additional","affiliation":[{"name":"Laboratory of Gastrointestinal Mucosal Immunology, Chung-Ang University College of Medicine, Seoul, Korea."},{"name":"Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0938-6697","authenticated-orcid":false,"given":"Beom Jin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4841-9404","authenticated-orcid":false,"given":"Jae Gyu","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","published-online":{"date-parts":[[2022]]},"reference":[{"issue":"3","key":"10.3346\/jkms.2022.37.e220_ref1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3322\/caac.21660","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"issue":"1","key":"10.3346\/jkms.2022.37.e220_ref2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5230\/jgc.2019.19.e8","volume":"19","author":"Guideline Committee of the Korean Gastric Cancer Association (KGCA), Development Working Group & Review Panel","year":"2019","journal-title":"J Gastric Cancer"},{"issue":"3","key":"10.3346\/jkms.2022.37.e220_ref3","doi-asserted-by":"crossref","first-page":"235","DOI":"10.5230\/jgc.2019.19.e25","volume":"19","author":"Jeon","year":"2019","journal-title":"J Gastric Cancer"},{"issue":"4","key":"10.3346\/jkms.2022.37.e220_ref4","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.tibtech.2017.12.005","volume":"36","author":"Aboulkheyr Es","year":"2018","journal-title":"Trends Biotechnol"},{"issue":"2","key":"10.3346\/jkms.2022.37.e220_ref5","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1136\/gutjnl-2017-314549","volume":"68","author":"Seidlitz","year":"2019","journal-title":"Gut"},{"issue":"6","key":"10.3346\/jkms.2022.37.e220_ref6","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.stem.2018.09.016","volume":"23","author":"Yan","year":"2018","journal-title":"Cell Stem Cell"},{"issue":"1","key":"10.3346\/jkms.2022.37.e220_ref7","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.jcmgh.2018.09.008","volume":"7","author":"Steele","year":"2019","journal-title":"Cell Mol Gastroenterol Hepatol"},{"issue":"15","key":"10.3346\/jkms.2022.37.e220_ref8","doi-asserted-by":"crossref","first-page":"2884","DOI":"10.1016\/j.jmb.2019.05.031","volume":"431","author":"Wallaschek","year":"2019","journal-title":"J Mol Biol"},{"issue":"4","key":"10.3346\/jkms.2022.37.e220_ref9","doi-asserted-by":"crossref","first-page":"878","DOI":"10.3904\/kjim.2020.474","volume":"36","author":"Nam","year":"2021","journal-title":"Korean J Intern Med"}],"container-title":["Journal of Korean Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jkms.org\/pdf\/10.3346\/jkms.2022.37.e220","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2022.37.e220","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2022.37.e220","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,17]],"date-time":"2022-07-17T20:08:39Z","timestamp":1658088519000},"score":1,"resource":{"primary":{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2022.37.e220"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":9,"journal-issue":{"issue":"28","published-online":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.3346\/jkms.2022.37.e220","relation":{},"ISSN":["1011-8934","1598-6357"],"issn-type":[{"value":"1011-8934","type":"print"},{"value":"1598-6357","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]},"assertion":[{"value":"2022-03-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-15","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-05","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2022 The Korean Academy of Medical Sciences.","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}],"article-number":"e220"}}