{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T18:27:23Z","timestamp":1793212043245,"version":"4.5.0"},"reference-count":52,"publisher":"XMLink","issue":"22","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2021R1A6A1A03038899"],"award-info":[{"award-number":["NRF-2021R1A6A1A03038899"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jkms.org"],"crossmark-restriction":false},"short-container-title":["J Korean Med Sci"],"DOI":"10.3346\/jkms.2023.38.e172","type":"journal-article","created":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T05:15:56Z","timestamp":1683522956000},"update-policy":"https:\/\/doi.org\/10.3346\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Pregnancy Outcomes Associated With Biologic Agent Exposure in Patients With Several Rheumatic Diseases and Inflammatory Bowel Diseases"],"prefix":"10.3346","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9213-9768","authenticated-orcid":false,"given":"Soo Min","family":"Ahn","sequence":"first","affiliation":[{"name":"Division of Rheumatology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5580-8996","authenticated-orcid":false,"given":"Young Bin","family":"Joo","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea."},{"name":"Hanyang University Institute for Rheumatology Research, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3202-2696","authenticated-orcid":false,"given":"Yun Jin","family":"Kim","sequence":"additional","affiliation":[{"name":"Biostatistical Consulting and Research Lab, Medical Research Collaborating Center, Hanyang University, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4699-9350","authenticated-orcid":false,"given":"So-Young","family":"Bang","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea."},{"name":"Hanyang University Institute for Rheumatology Research, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8535-0442","authenticated-orcid":false,"given":"Hye-Soon","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea."},{"name":"Hanyang University Institute for Rheumatology Research, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","published-online":{"date-parts":[[2023]]},"reference":[{"key":"10.3346\/jkms.2023.38.e172_ref1","doi-asserted-by":"crossref","first-page":"102303","DOI":"10.1016\/j.jaut.2019.07.002","volume":"105","author":"Agrawal","year":"2019","journal-title":"J Autoimmun"},{"issue":"0","key":"10.3346\/jkms.2023.38.e172_ref2","doi-asserted-by":"crossref","first-page":"2","DOI":"10.3899\/jrheum.091461","volume":"85","author":"El-Gabalawy","year":"2010","journal-title":"J Rheumatol Suppl"},{"issue":"Suppl 1","key":"10.3346\/jkms.2023.38.e172_ref3","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1097\/01.MIB.0000195385.19268.68","volume":"12","author":"Hanauer","year":"2006","journal-title":"Inflamm Bowel Dis"},{"key":"10.3346\/jkms.2023.38.e172_ref4","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.bpobgyn.2019.09.005","volume":"64","author":"Littlejohn","year":"2020","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"10.3346\/jkms.2023.38.e172_ref5","doi-asserted-by":"crossref","first-page":"102676","DOI":"10.1016\/j.jaut.2021.102676","volume":"122","author":"Barenbrug","year":"2021","journal-title":"J Autoimmun"},{"issue":"2","key":"10.3346\/jkms.2023.38.e172_ref6","doi-asserted-by":"crossref","first-page":"60","DOI":"10.4078\/jrd.2021.28.2.60","volume":"28","author":"Kim","year":"2021","journal-title":"J Rheum Dis"},{"issue":"23","key":"10.3346\/jkms.2023.38.e172_ref7","doi-asserted-by":"crossref","first-page":"7123","DOI":"10.3748\/wjg.v20.i23.7123","volume":"20","author":"Palomba","year":"2014","journal-title":"World J Gastroenterol"},{"issue":"Suppl 2","key":"10.3346\/jkms.2023.38.e172_ref8","first-page":"866","volume":"77","author":"Tincani","year":"2018","journal-title":"Ann Rheum Dis"},{"issue":"6","key":"10.3346\/jkms.2023.38.e172_ref9","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1007\/s00404-022-06463-x","volume":"306","author":"Allen","year":"2022","journal-title":"Arch Gynecol Obstet"},{"issue":"16","key":"10.3346\/jkms.2023.38.e172_ref10","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1007\/s40265-020-01376-y","volume":"80","author":"Ghalandari","year":"2020","journal-title":"Drugs"},{"issue":"2","key":"10.3346\/jkms.2023.38.e172_ref11","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1136\/annrheumdis-2017-211555","volume":"77","author":"Baker","year":"2018","journal-title":"Ann Rheum Dis"},{"issue":"978","key":"10.3346\/jkms.2023.38.e172_ref12","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1136\/pgmj.2006.052688","volume":"83","author":"Kuek","year":"2007","journal-title":"Postgrad Med J"},{"issue":"4","key":"10.3346\/jkms.2023.38.e172_ref13","doi-asserted-by":"crossref","first-page":"176","DOI":"10.4078\/jrd.2021.28.4.176","volume":"28","author":"Kim","year":"2021","journal-title":"J Rheum Dis"},{"issue":"3","key":"10.3346\/jkms.2023.38.e172_ref14","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1053\/j.gastro.2015.12.003","volume":"150","author":"Nguyen","year":"2016","journal-title":"Gastroenterology"},{"issue":"5","key":"10.3346\/jkms.2023.38.e172_ref15","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1053\/j.gastro.2018.12.022","volume":"156","author":"Mahadevan","year":"2019","journal-title":"Gastroenterology"},{"issue":"4","key":"10.3346\/jkms.2023.38.e172_ref16","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1002\/art.41191","volume":"72","author":"Sammaritano","year":"2020","journal-title":"Arthritis Rheumatol"},{"issue":"3","key":"10.3346\/jkms.2023.38.e172_ref17","doi-asserted-by":"crossref","first-page":"119","DOI":"10.4078\/jrd.2021.28.3.119","volume":"28","author":"Park","year":"2021","journal-title":"J Rheum Dis"},{"issue":"1","key":"10.3346\/jkms.2023.38.e172_ref18","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1001\/jamainternmed.2019.4644","volume":"180","author":"Kim","year":"2020","journal-title":"JAMA Intern Med"},{"issue":"5","key":"10.3346\/jkms.2023.38.e172_ref19","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","volume":"40","author":"Charlson","year":"1987","journal-title":"J Chronic Dis"},{"issue":"11","key":"10.3346\/jkms.2023.38.e172_ref20","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1097\/01.mlr.0000182534.19832.83","volume":"43","author":"Quan","year":"2005","journal-title":"Med Care"},{"issue":"1","key":"10.3346\/jkms.2023.38.e172_ref21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/art.39480","volume":"68","author":"Singh","year":"2016","journal-title":"Arthritis Rheumatol"},{"issue":"7","key":"10.3346\/jkms.2023.38.e172_ref22","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1002\/acr.23434","volume":"70","author":"Tsao","year":"2018","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"9","key":"10.3346\/jkms.2023.38.e172_ref23","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1111\/apt.15654","volume":"51","author":"Lee","year":"2020","journal-title":"Aliment Pharmacol Ther"},{"issue":"37","key":"10.3346\/jkms.2023.38.e172_ref24","doi-asserted-by":"crossref","first-page":"e238","DOI":"10.3346\/jkms.2019.34.e238","volume":"34","author":"Lee","year":"2019","journal-title":"J Korean Med Sci"},{"key":"10.3346\/jkms.2023.38.e172_ref25","doi-asserted-by":"crossref","first-page":"279","DOI":"10.3389\/fphar.2019.00279","volume":"10","author":"Baumgart","year":"2019","journal-title":"Front Pharmacol"},{"issue":"3","key":"10.3346\/jkms.2023.38.e172_ref26","doi-asserted-by":"crossref","first-page":"721","DOI":"10.3904\/kjim.2019.144","volume":"36","author":"Park","year":"2021","journal-title":"Korean J Intern Med"},{"issue":"12","key":"10.3346\/jkms.2023.38.e172_ref27","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1046\/j.1600-0412.2003.00259.x","volume":"82","author":"Bartha","year":"2003","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"3","key":"10.3346\/jkms.2023.38.e172_ref28","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1002\/pds.4930","volume":"29","author":"Br\u00f6ms","year":"2020","journal-title":"Pharmacoepidemiol Drug Saf"},{"issue":"1","key":"10.3346\/jkms.2023.38.e172_ref29","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.22374\/1710-6222.25.1.5","volume":"25","author":"Mirdamadi","year":"2018","journal-title":"J Popul Ther Clin Pharmacol"},{"issue":"1","key":"10.3346\/jkms.2023.38.e172_ref30","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1186\/s12884-019-2300-0","volume":"19","author":"Kim","year":"2019","journal-title":"BMC Pregnancy Childbirth"},{"issue":"11","key":"10.3346\/jkms.2023.38.e172_ref31","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1111\/1471-0528.13946","volume":"123","author":"Shand","year":"2016","journal-title":"BJOG"},{"issue":"6","key":"10.3346\/jkms.2023.38.e172_ref32","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1002\/art.30210","volume":"63","author":"Wallenius","year":"2011","journal-title":"Arthritis Rheum"},{"issue":"5","key":"10.3346\/jkms.2023.38.e172_ref33","doi-asserted-by":"crossref","first-page":"668","DOI":"10.3899\/jrheum.190754","volume":"47","author":"Lee","year":"2020","journal-title":"J Rheumatol"},{"issue":"6","key":"10.3346\/jkms.2023.38.e172_ref34","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1034\/j.1600-0412.2000.079006490.x","volume":"79","author":"Skomsvoll","year":"2000","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"9","key":"10.3346\/jkms.2023.38.e172_ref35","doi-asserted-by":"crossref","first-page":"2765","DOI":"10.1002\/art.22053","volume":"54","author":"Dessein","year":"2006","journal-title":"Arthritis Rheum"},{"key":"10.3346\/jkms.2023.38.e172_ref36","doi-asserted-by":"crossref","first-page":"6712901","DOI":"10.1155\/2018\/6712901","volume":"2018","author":"Paschou","year":"2018","journal-title":"Int J Endocrinol"},{"issue":"8","key":"10.3346\/jkms.2023.38.e172_ref37","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.3390\/jcm11082109","volume":"11","author":"Nam","year":"2022","journal-title":"J Clin Med"},{"issue":"5","key":"10.3346\/jkms.2023.38.e172_ref38","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1136\/annrheumdis-2020-219140","volume":"80","author":"Baker","year":"2021","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"10.3346\/jkms.2023.38.e172_ref39","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/acr.20657","volume":"64","author":"Antohe","year":"2012","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"10.3346\/jkms.2023.38.e172_ref40","doi-asserted-by":"crossref","first-page":"105216","DOI":"10.1016\/j.phrs.2020.105216","volume":"161","author":"Lin","year":"2020","journal-title":"Pharmacol Res"},{"issue":"7","key":"10.3346\/jkms.2023.38.e172_ref41","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.placenta.2015.04.006","volume":"36","author":"Pantham","year":"2015","journal-title":"Placenta"},{"issue":"3","key":"10.3346\/jkms.2023.38.e172_ref42","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1095\/biolreprod54.3.554","volume":"54","author":"Hunt","year":"1996","journal-title":"Biol Reprod"},{"issue":"6","key":"10.3346\/jkms.2023.38.e172_ref43","doi-asserted-by":"crossref","first-page":"2922","DOI":"10.3390\/ijms22062922","volume":"22","author":"Romanowska-Pr\u00f3chnicka","year":"2021","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.3346\/jkms.2023.38.e172_ref44","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/s12016-016-8596-x","volume":"53","author":"Alijotas-Reig","year":"2017","journal-title":"Clin Rev Allergy Immunol"},{"issue":"12","key":"10.3346\/jkms.2023.38.e172_ref45","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.1111\/j.1572-0241.2004.30186.x","volume":"99","author":"Katz","year":"2004","journal-title":"Am J Gastroenterol"},{"issue":"8","key":"10.3346\/jkms.2023.38.e172_ref46","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1111\/1471-0528.17093","volume":"129","author":"O\u2019Byrne","year":"2022","journal-title":"BJOG"},{"issue":"2","key":"10.3346\/jkms.2023.38.e172_ref47","doi-asserted-by":"crossref","first-page":"237","DOI":"10.5217\/ir.2018.00071","volume":"17","author":"Lee","year":"2019","journal-title":"Intest Res"},{"issue":"5","key":"10.3346\/jkms.2023.38.e172_ref48","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1111\/j.1365-2036.2005.02384.x","volume":"21","author":"Agret","year":"2005","journal-title":"Aliment Pharmacol Ther"},{"issue":"11","key":"10.3346\/jkms.2023.38.e172_ref49","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1093\/rheumatology\/ker302","volume":"50","author":"Hazes","year":"2011","journal-title":"Rheumatology (Oxford)"},{"issue":"7","key":"10.3346\/jkms.2023.38.e172_ref50","first-page":"464","volume":"21","author":"Andreoli","year":"2019","journal-title":"Isr Med Assoc J"},{"issue":"Suppl 1","key":"10.3346\/jkms.2023.38.e172_ref51","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1159\/000502886","volume":"101","author":"Restellini","year":"2020","journal-title":"Digestion"},{"key":"10.3346\/jkms.2023.38.e172_ref52","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jaut.2016.11.004","volume":"76","author":"Komaki","year":"2017","journal-title":"J Autoimmun"}],"container-title":["Journal of Korean Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jkms.org\/pdf\/10.3346\/jkms.2023.38.e172","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2023.38.e172","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2023.38.e172","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,12]],"date-time":"2023-12-12T08:14:30Z","timestamp":1702368870000},"score":1,"resource":{"primary":{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2023.38.e172"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":52,"journal-issue":{"issue":"22","published-online":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.3346\/jkms.2023.38.e172","relation":{},"ISSN":["1011-8934","1598-6357"],"issn-type":[{"value":"1011-8934","type":"print"},{"value":"1598-6357","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]},"assertion":[{"value":"2022-11-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-21","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-08","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2023 The Korean Academy of Medical Sciences.","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}],"article-number":"e172"}}