{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T03:56:11Z","timestamp":1775620571058,"version":"3.50.1"},"reference-count":39,"publisher":"XMLink","issue":"26","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["jkms.org"],"crossmark-restriction":false},"short-container-title":["J Korean Med Sci"],"DOI":"10.3346\/jkms.2024.39.e200","type":"journal-article","created":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T05:20:54Z","timestamp":1718342454000},"update-policy":"https:\/\/doi.org\/10.3346\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Machine Learning-Based Identification of Diagnostic Biomarkers for Korean Male Sarcopenia Through Integrative DNA Methylation and Methylation Risk Score: From the Korean Genomic Epidemiology Study (KoGES)"],"prefix":"10.3346","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4590-2214","authenticated-orcid":false,"given":"Seohyun","family":"Ahn","sequence":"first","affiliation":[{"name":"Health and Exercise Science Laboratory, Institute of Sport Science, Department of Physical Education, Seoul National University, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4493-250X","authenticated-orcid":false,"given":"Yunho","family":"Sung","sequence":"additional","affiliation":[{"name":"Health and Exercise Science Laboratory, Institute of Sport Science, Department of Physical Education, Seoul National University, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8825-6259","authenticated-orcid":false,"given":"Wook","family":"Song","sequence":"additional","affiliation":[{"name":"Health and Exercise Science Laboratory, Institute of Sport Science, Department of Physical Education, Seoul National University, Seoul, Korea."},{"name":"Institute on Aging, Seoul National University, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18617","published-online":{"date-parts":[[2024]]},"reference":[{"issue":"2","key":"10.3346\/jkms.2024.39.e200_ref1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jamda.2013.11.025","volume":"15","author":"Chen","year":"2014","journal-title":"J Am Med Dir Assoc"},{"issue":"3","key":"10.3346\/jkms.2024.39.e200_ref2","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1007\/s11357-012-9384-z","volume":"35","author":"Bijlsma","year":"2013","journal-title":"Age (Dordr)"},{"issue":"3","key":"10.3346\/jkms.2024.39.e200_ref3","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.apmr.2016.07.015","volume":"98","author":"Ryan","year":"2017","journal-title":"Arch Phys Med Rehabil"},{"issue":"1","key":"10.3346\/jkms.2024.39.e200_ref4","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/s12902-019-0432-x","volume":"19","author":"Du","year":"2019","journal-title":"BMC Endocr Disord"},{"issue":"1","key":"10.3346\/jkms.2024.39.e200_ref5","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1186\/s12877-022-03704-1","volume":"22","author":"Chew","year":"2022","journal-title":"BMC Geriatr"},{"issue":"6","key":"10.3346\/jkms.2024.39.e200_ref6","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.jamda.2020.03.018","volume":"21","author":"Kim","year":"2020","journal-title":"J Am Med Dir Assoc"},{"issue":"1","key":"10.3346\/jkms.2024.39.e200_ref7","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1365-2605.2007.00757.x","volume":"31","author":"Haren","year":"2008","journal-title":"Int J Androl"},{"issue":"6","key":"10.3346\/jkms.2024.39.e200_ref8","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1177\/1947601910393957","volume":"2","author":"Jin","year":"2011","journal-title":"Genes Cancer"},{"issue":"4","key":"10.3346\/jkms.2024.39.e200_ref9","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.cell.2014.10.039","volume":"159","author":"Kennedy","year":"2014","journal-title":"Cell"},{"issue":"6245","key":"10.3346\/jkms.2024.39.e200_ref10","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1126\/science.aaa8415","volume":"349","author":"Jordan","year":"2015","journal-title":"Science"},{"issue":"3","key":"10.3346\/jkms.2024.39.e200_ref11","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.acra.2019.03.011","volume":"27","author":"Burns","year":"2020","journal-title":"Acad Radiol"},{"issue":"43","key":"10.3346\/jkms.2024.39.e200_ref12","doi-asserted-by":"crossref","first-page":"e17699","DOI":"10.1097\/MD.0000000000017699","volume":"98","author":"Kang","year":"2019","journal-title":"Medicine (Baltimore)"},{"issue":"5","key":"10.3346\/jkms.2024.39.e200_ref13","doi-asserted-by":"crossref","first-page":"822","DOI":"10.2174\/0929867328666210917115733","volume":"29","author":"Ao","year":"2022","journal-title":"Curr Med Chem"},{"issue":"2","key":"10.3346\/jkms.2024.39.e200_ref14","doi-asserted-by":"crossref","first-page":"e20","DOI":"10.1093\/ije\/dyv316","volume":"46","author":"Kim","year":"2017","journal-title":"Int J Epidemiol"},{"issue":"3","key":"10.3346\/jkms.2024.39.e200_ref15","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jamda.2019.12.012","volume":"21","author":"Chen","year":"2020","journal-title":"J Am Med Dir Assoc"},{"issue":"4","key":"10.3346\/jkms.2024.39.e200_ref16","first-page":"551","volume":"20","author":"Wen","year":"2011","journal-title":"Asia Pac J Clin Nutr"},{"key":"10.3346\/jkms.2024.39.e200_ref17","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.nut.2018.05.031","volume":"57","author":"Wigodski","year":"2019","journal-title":"Nutrition"},{"issue":"8","key":"10.3346\/jkms.2024.39.e200_ref18","doi-asserted-by":"crossref","first-page":"e110","DOI":"10.1093\/gerona\/glab085","volume":"76","author":"Kim","year":"2021","journal-title":"J Gerontol A Biol Sci Med Sci"},{"issue":"6","key":"10.3346\/jkms.2024.39.e200_ref19","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1002\/jcsm.12834","volume":"12","author":"Linge","year":"2021","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"10.3346\/jkms.2024.39.e200_ref20","doi-asserted-by":"crossref","first-page":"986236","DOI":"10.3389\/fonc.2022.986236","volume":"12","author":"Bolte","year":"2022","journal-title":"Front Oncol"},{"issue":"4","key":"10.3346\/jkms.2024.39.e200_ref21","doi-asserted-by":"crossref","first-page":"92","DOI":"10.3390\/jfmk7040092","volume":"7","author":"Oshita","year":"2022","journal-title":"J Funct Morphol Kinesiol"},{"issue":"24","key":"10.3346\/jkms.2024.39.e200_ref22","doi-asserted-by":"crossref","first-page":"3982","DOI":"10.1093\/bioinformatics\/btx513","volume":"33","author":"Tian","year":"2017","journal-title":"Bioinformatics"},{"issue":"1","key":"10.3346\/jkms.2024.39.e200_ref23","doi-asserted-by":"crossref","first-page":"8946","DOI":"10.1038\/s41598-019-45346-1","volume":"9","author":"Unruh","year":"2019","journal-title":"Sci Rep"},{"issue":"1","key":"10.3346\/jkms.2024.39.e200_ref24","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s13148-018-0541-9","volume":"10","author":"Chandra","year":"2018","journal-title":"Clin Epigenetics"},{"key":"10.3346\/jkms.2024.39.e200_ref25","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.ebiom.2019.07.006","volume":"46","author":"Ringh","year":"2019","journal-title":"EBioMedicine"},{"issue":"3","key":"10.3346\/jkms.2024.39.e200_ref26","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1007\/s10489-017-0992-2","volume":"48","author":"Huang","year":"2018","journal-title":"Appl Intell"},{"issue":"35","key":"10.3346\/jkms.2024.39.e200_ref27","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.21105\/joss.01075","volume":"4","author":"Bengfort","year":"2019","journal-title":"J Open Source Softw"},{"key":"10.3346\/jkms.2024.39.e200_ref28","first-page":"10","volume":"3","author":"Batista","year":"2003","journal-title":"Wob"},{"issue":"1","key":"10.3346\/jkms.2024.39.e200_ref29","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/s41525-022-00320-1","volume":"7","author":"Thompson","year":"2022","journal-title":"NPJ Genom Med"},{"issue":"9","key":"10.3346\/jkms.2024.39.e200_ref30","doi-asserted-by":"crossref","first-page":"R102","DOI":"10.1186\/gb-2013-14-9-r102","volume":"14","author":"Day","year":"2013","journal-title":"Genome Biol"},{"issue":"1","key":"10.3346\/jkms.2024.39.e200_ref31","doi-asserted-by":"crossref","first-page":"15360","DOI":"10.1038\/s41598-020-72730-z","volume":"10","author":"Turner","year":"2020","journal-title":"Sci Rep"},{"issue":"2","key":"10.3346\/jkms.2024.39.e200_ref32","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1111\/acel.12180","volume":"13","author":"Zykovich","year":"2014","journal-title":"Aging Cell"},{"key":"10.3346\/jkms.2024.39.e200_ref33","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.yjmcc.2013.03.005","volume":"58","author":"Marx","year":"2013","journal-title":"J Mol Cell Cardiol"},{"issue":"2","key":"10.3346\/jkms.2024.39.e200_ref34","doi-asserted-by":"crossref","first-page":"e162891","DOI":"10.1172\/JCI162891","volume":"133","author":"Marks","year":"2023","journal-title":"J Clin Invest"},{"issue":"10","key":"10.3346\/jkms.2024.39.e200_ref35","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1359\/jbmr.2003.18.10.1740","volume":"18","author":"Frattini","year":"2003","journal-title":"J Bone Miner Res"},{"issue":"8","key":"10.3346\/jkms.2024.39.e200_ref36","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1002\/jbmr.4322","volume":"36","author":"R\u00f6ssler","year":"2021","journal-title":"J Bone Miner Res"},{"key":"10.3346\/jkms.2024.39.e200_ref37","doi-asserted-by":"crossref","first-page":"978879","DOI":"10.3389\/fped.2023.978879","volume":"11","author":"Wang","year":"2023","journal-title":"Front Pediatr"},{"issue":"4","key":"10.3346\/jkms.2024.39.e200_ref38","doi-asserted-by":"crossref","first-page":"e16834","DOI":"10.15252\/emmm.202216834","volume":"15","author":"El-Gazzar","year":"2023","journal-title":"EMBO Mol Med"},{"issue":"4","key":"10.3346\/jkms.2024.39.e200_ref39","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/s41584-023-00921-9","volume":"19","author":"Bennett","year":"2023","journal-title":"Nat Rev Rheumatol"}],"container-title":["Journal of Korean Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jkms.org\/pdf\/10.3346\/jkms.2024.39.e200","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2024.39.e200","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2024.39.e200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,7]],"date-time":"2024-07-07T23:29:41Z","timestamp":1720394981000},"score":1,"resource":{"primary":{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2024.39.e200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":39,"journal-issue":{"issue":"26","published-online":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.3346\/jkms.2024.39.e200","relation":{},"ISSN":["1011-8934","1598-6357"],"issn-type":[{"value":"1011-8934","type":"print"},{"value":"1598-6357","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]},"assertion":[{"value":"2024-01-17","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-21","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-25","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2024 The Korean Academy of Medical Sciences.","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}],"article-number":"e200"}}