{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T05:22:59Z","timestamp":1793856179464,"version":"4.6.1"},"reference-count":25,"publisher":"XMLink","issue":"39","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","award":["HI19C1298"],"award-info":[{"award-number":["HI19C1298"]}],"id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jkms.org"],"crossmark-restriction":false},"short-container-title":["J Korean Med Sci"],"DOI":"10.3346\/jkms.2025.40.e259","type":"journal-article","created":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:15:27Z","timestamp":1756368927000},"update-policy":"https:\/\/doi.org\/10.3346\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Long-Term Safety of Tofacitinib for Treatment of Moderate-to-Severe Ulcerative Colitis: Three Years of Korean National Data"],"prefix":"10.3346","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2428-1551","authenticated-orcid":false,"given":"Eun Mi","family":"Song","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7414-0258","authenticated-orcid":false,"given":"Gi Hyeon","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Healthcare Review and Assessment Committee, Health Insurance Review and Assessment Service, Wonju, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9075-2027","authenticated-orcid":false,"given":"Sung Hoon","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","published-online":{"date-parts":[[2025]]},"reference":[{"issue":"1","key":"10.3346\/jkms.2025.40.e259_ref1","doi-asserted-by":"crossref","first-page":"54","DOI":"10.5217\/ir.2018.00096","volume":"17","author":"Yen","year":"2019","journal-title":"Intest Res"},{"issue":"4","key":"10.3346\/jkms.2025.40.e259_ref2","doi-asserted-by":"crossref","first-page":"345","DOI":"10.5217\/ir.2020.00121","volume":"18","author":"Hong","year":"2020","journal-title":"Intest Res"},{"issue":"4","key":"10.3346\/jkms.2025.40.e259_ref3","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.crohns.2010.04.004","volume":"4","author":"Allez","year":"2010","journal-title":"J Crohn\u2019s Colitis"},{"issue":"4","key":"10.3346\/jkms.2025.40.e259_ref4","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1038\/ajg.2011.60","volume":"106","author":"Billioud","year":"2011","journal-title":"Am J Gastroenterol"},{"issue":"11","key":"10.3346\/jkms.2025.40.e259_ref5","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.1097\/MIB.0b013e3182a19268","volume":"19","author":"Buisson","year":"2013","journal-title":"Inflamm Bowel Dis"},{"issue":"24","key":"10.3346\/jkms.2025.40.e259_ref6","doi-asserted-by":"crossref","first-page":"8468","DOI":"10.1021\/jm1004286","volume":"53","author":"Flanagan","year":"2010","journal-title":"J Med Chem"},{"issue":"11","key":"10.3346\/jkms.2025.40.e259_ref7","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1111\/apt.17509","volume":"57","author":"Olivera","year":"2023","journal-title":"Aliment Pharmacol Ther"},{"issue":"1","key":"10.3346\/jkms.2025.40.e259_ref8","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.cgh.2020.10.004","volume":"20","author":"Colombel","year":"2022","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"4","key":"10.3346\/jkms.2025.40.e259_ref9","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1111\/apt.16712","volume":"55","author":"Sandborn","year":"2022","journal-title":"Aliment Pharmacol Ther"},{"issue":"6","key":"10.3346\/jkms.2025.40.e259_ref10","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1053\/j.gastro.2020.01.001","volume":"158","author":"Olivera","year":"2020","journal-title":"Gastroenterology"},{"issue":"8","key":"10.3346\/jkms.2025.40.e259_ref11","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1016\/j.cgh.2018.11.035","volume":"17","author":"Sandborn","year":"2019","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"10","key":"10.3346\/jkms.2025.40.e259_ref12","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1111\/apt.15514","volume":"50","author":"Sandborn","year":"2019","journal-title":"Aliment Pharmacol Ther"},{"issue":"4","key":"10.3346\/jkms.2025.40.e259_ref13","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1056\/NEJMoa2109927","volume":"386","author":"Ytterberg","year":"2022","journal-title":"N Engl J Med"},{"issue":"1","key":"10.3346\/jkms.2025.40.e259_ref14","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1136\/ard-2022-222259","volume":"82","author":"Charles-Schoeman","year":"2023","journal-title":"Ann Rheum Dis"},{"issue":"4","key":"10.3346\/jkms.2025.40.e259_ref15","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1002\/bjs.4454","volume":"91","author":"Cheuk","year":"2004","journal-title":"Br J Surg"},{"issue":"3","key":"10.3346\/jkms.2025.40.e259_ref16","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.thromres.2012.05.025","volume":"130","author":"Cohen","year":"2012","journal-title":"Thromb Res"},{"issue":"1","key":"10.3346\/jkms.2025.40.e259_ref17","first-page":"15017644","volume":"15","author":"Huang","year":"2016","journal-title":"Genet Mol Res"},{"issue":"8","key":"10.3346\/jkms.2025.40.e259_ref18","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1093\/ibd\/izy058","volume":"24","author":"Weng","year":"2018","journal-title":"Inflamm Bowel Dis"},{"issue":"4","key":"10.3346\/jkms.2025.40.e259_ref19","doi-asserted-by":"crossref","first-page":"555","DOI":"10.5009\/gnl210190","volume":"16","author":"Kim","year":"2022","journal-title":"Gut Liver"},{"issue":"3","key":"10.3346\/jkms.2025.40.e259_ref20","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.thromres.2014.12.025","volume":"135","author":"Chung","year":"2015","journal-title":"Thromb Res"},{"issue":"3","key":"10.3346\/jkms.2025.40.e259_ref21","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1055\/s-0037-1615600","volume":"85","author":"Bernstein","year":"2001","journal-title":"Thromb Haemost"},{"issue":"10","key":"10.3346\/jkms.2025.40.e259_ref22","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1111\/jgh.15923","volume":"37","author":"Matsuoka","year":"2022","journal-title":"J Gastroenterol Hepatol"},{"issue":"12","key":"10.3346\/jkms.2025.40.e259_ref23","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1016\/j.cgh.2018.05.024","volume":"16","author":"Chang","year":"2018","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"1","key":"10.3346\/jkms.2025.40.e259_ref24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/gene.2014.51","volume":"16","author":"Crosslin","year":"2015","journal-title":"Genes Immun"},{"issue":"RR-3","key":"10.3346\/jkms.2025.40.e259_ref25","first-page":"1","volume":"59","author":"Marin","year":"2010","journal-title":"MMWR Recomm Rep"}],"container-title":["Journal of Korean Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jkms.org\/pdf\/10.3346\/jkms.2025.40.e259","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2025.40.e259","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2025.40.e259","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:26:23Z","timestamp":1760315183000},"score":1,"resource":{"primary":{"URL":"https:\/\/jkms.org\/DOIx.php?id=10.3346\/jkms.2025.40.e259"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":25,"journal-issue":{"issue":"39","published-online":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.3346\/jkms.2025.40.e259","relation":{},"ISSN":["1011-8934","1598-6357"],"issn-type":[{"value":"1011-8934","type":"print"},{"value":"1598-6357","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"2024-08-23","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-27","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2025 The Korean Academy of Medical Sciences.","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}],"article-number":"e259"}}