{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T10:20:15Z","timestamp":1792491615151,"version":"4.5.0"},"reference-count":37,"publisher":"Korean Society for Parasitology","issue":"2","license":[{"start":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T00:00:00Z","timestamp":1588204800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"name":"National Council of Science and Technology"}],"content-domain":{"domain":["parasitol.kr"],"crossmark-restriction":true},"short-container-title":["Korean J Parasitol"],"abstract":"<jats:p>Infections caused by &lt;i&gt;Trichomonas vaginalis&lt;\/i&gt; in humans are one of the main public health problems caused by sexually transmitted diseases. Objective of this study was to evaluate potential biological activity of the medicinal plant &lt;i&gt;Argemone mexicana&lt;\/i&gt; (Mexican poppy) on &lt;i&gt;T. vaginalis&lt;\/i&gt;. Methanolic extracts of the stems and leaves of &lt;i&gt;A. mexicana&lt;\/i&gt;, and different fractions were prepared with solvents of different polarities. The extracts and functional groups were detected containing sterols, triterpenes, quinones, flavonoids and, alkaloids. Extracts from both the stems and leaves of &lt;i&gt;A. mexicana&lt;\/i&gt; inhibited the growth of &lt;i&gt;T. vaginalis&lt;\/i&gt; with half-maximal inhibitory concentration value of 70.6 and 67.2 \u03bcg\/ml, respectively. In the active fractions, the most abundant compounds were berberine and jatrorrhizine, with presumed antiparasitic activity.<\/jats:p>","DOI":"10.3347\/kjp.2020.58.2.135","type":"journal-article","created":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T12:52:14Z","timestamp":1588251134000},"page":"135-145","update-policy":"https:\/\/doi.org\/10.3347\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["In Vitro Effect of Methanolic Extract of Argemone mexicana against Trichomonas vaginalis"],"prefix":"10.3347","volume":"58","author":[{"given":"Joel Horacio","family":"Elizondo-Luevano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Verde-Star","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azucena","family":"Gonz\u00e1lez-Horta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roc\u00edo","family":"Castro-R\u00edos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magda Elizabeth","family":"Hern\u00e1ndez-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abelardo","family":"Ch\u00e1vez-Montes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1900","published-online":{"date-parts":[[2020,4,30]]},"reference":[{"key":"ref1","first-page":"307","volume-title":"<italic>Trichomonas vaginalis<\/italic>: a review of epidemiologic, clinical and treatment issues","author":"Kissinger","year":"2015"},{"key":"ref2","first-page":"123","volume-title":"Trichomoniasis: challenges to Appropriate Management","author":"Wendel","year":"2007"},{"key":"ref3","first-page":"e704","volume-title":"Health in times of uncertainty in the eastern Mediterranean region, 1990\u20132013: a systematic analysis for the Global Burden of Disease Study 2013","author":"Mokdad","year":"2016"},{"key":"ref4","first-page":"337","volume-title":"Effect of different extracts from Celosia argentea on calcium and phosphate inhibition in vitro","author":"Patel","year":"2011"},{"key":"ref5","first-page":"45","volume-title":"Plant profile, phytochemistry and pharmacology of <italic>Argemone Mexicana<\/italic> Linn. 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Mosyakin &amp; Clemants in an amoebic liver abscess hamster model","author":"\u00c1vila-Blanco","year":"2014"}],"container-title":["The Korean Journal of Parasitology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/parasitol.kr\/upload\/pdf\/kjp-58-2-135.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,13]],"date-time":"2020-05-13T07:34:57Z","timestamp":1589355297000},"score":1,"resource":{"primary":{"URL":"http:\/\/parasitol.kr\/journal\/view.php?doi=10.3347\/kjp.2020.58.2.135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,30]]},"references-count":37,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,4]]}},"URL":"https:\/\/doi.org\/10.3347\/kjp.2020.58.2.135","relation":{},"ISSN":["0023-4001","1738-0006"],"issn-type":[{"value":"0023-4001","type":"print"},{"value":"1738-0006","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,30]]},"assertion":[{"value":"2019-10-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-09","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}