{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T01:40:43Z","timestamp":1777340443552,"version":"3.51.4"},"reference-count":32,"publisher":"Korean Society for Parasitology","issue":"2","license":[{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100018688","name":"Korea Disease Control and Prevention Agency","doi-asserted-by":"crossref","award":["6332-305-210-13"],"award-info":[{"award-number":["6332-305-210-13"]}],"id":[{"id":"10.13039\/100018688","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100018688","name":"Korea Disease Control and Prevention Agency","doi-asserted-by":"crossref","award":["2025"],"award-info":[{"award-number":["2025"]}],"id":[{"id":"10.13039\/100018688","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["parahostdis.org"],"crossmark-restriction":true},"short-container-title":["PHD"],"abstract":"Until now, 3 Metagonimus spp. (<i>M. yokogawai<\/i>, <i>M. takahashii<\/i>, and <i>M. miyatai<\/i>) causing human metagonimiasis have been reported in Korea. In this study, we investigated the possible presence of Metagonimus spp. other than these 3 species using human fecal samples from an endemic area in Korea. DNA was extracted from Metagonimus egg-positive fecal samples collected from residents of Gurye-gun, Jeollanam-do. A total of 21 representative mitochondrial cytochrome <i>c<\/i> oxidase subunit I sequences were obtained by PCR and cloning, and sequencing. Phylogenetic analysis revealed 1 cluster corresponding to <i>M. yokogawai<\/i> (<i>n<\/i>=10) and 2 additional distinct clusters corresponding to M. kogai (<i>n<\/i>=8) and M. saitoi (<i>n<\/i>=3), which were proposed as new species in Japan in 2022. Pairwise cytochrome <i>c<\/i> oxidase subunit I distances were low for <i>M. yokogawai<\/i> and <i>M. kogai<\/i> (mean Kimura 2-parameter: 0.005\u20130.006), whereas <i>M. saitoi<\/i> showed higher Korea\u2013Japan values (~0.029), a pattern consistent with geographic structuring. In conclusion, we provide the first molecular evidence for the occurrence of M. kogai and M. saitoi in human fecal samples in Korea. Further confirmation using adult morphology, additional nuclear markers, and ecological surveys are needed to clarify metagonimiasis transmission in the Seomjin-gang (river) basin.<\/jats:p>","DOI":"10.3347\/phd.25071","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T07:07:38Z","timestamp":1773644858000},"page":"123-129","update-policy":"https:\/\/doi.org\/10.3347\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Molecular evidence for human Metagonimus kogai and M. saitoi infection in Korea: Detection of COI genes in the feces of riverside people along the Seomjin\u2011gang (river)"],"prefix":"10.3347","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-0291-4717","authenticated-orcid":true,"given":"Eunsol","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2708-2671","authenticated-orcid":true,"given":"Jong-Hun","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8514-6044","authenticated-orcid":true,"given":"Yeong-Ju","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5914-1561","authenticated-orcid":true,"given":"Seon-Ok","family":"Baek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1636-0639","authenticated-orcid":true,"given":"Hee-Il","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5248-6995","authenticated-orcid":true,"given":"Jung-Won","family":"Ju","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3369-0063","authenticated-orcid":true,"given":"Myeong-Ro","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3083-8424","authenticated-orcid":true,"given":"Tae Yun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1900","published-online":{"date-parts":[[2026,3,16]]},"reference":[{"key":"ref1","volume-title":"","author":"Chai","year":"2011"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(11)70294-8"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.fawpar.2017.09.001"},{"key":"ref4","volume-title":"","author":"Montresor","year":"1998"},{"key":"ref5","first-page":"373","volume-title":"Heterophyes in Japan","author":"Katsurada","year":"1912"},{"key":"ref6","first-page":"158","volume-title":"On a new parasite Metagonimus yokogawai<\/italic> with a trout, Plecoglossus altivelis<\/italic> (Temminck), as intermediate host: a new genus established","author":"Yokogawa","year":"1913"},{"key":"ref7","first-page":"26","volume-title":"Studies on trematodes whose second intermediate hosts are fishes from the brackish waters of Formosa","author":"Katsuta","year":"1932"},{"key":"ref8","first-page":"2687","volume-title":"On the life-history of Metagonimus yokogawai<\/italic>, a new species of Metagonimus<\/italic> and Exorchis major<\/italic>","author":"Takahashi","year":"1929"},{"key":"ref9","first-page":"365","volume-title":"Studies concerning a new species of Metagonimus<\/italic> and its life cycle","author":"Izumi","year":"1935"},{"key":"ref10","first-page":"167","volume-title":"A new trematode, Metagonimus otsurui<\/italic> sp. nov. from the fresh-water fishes (Trematoda: Heterophyidae)","author":"Saito","year":"1968"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.1997.35.4.223"},{"key":"ref12","first-page":"87","volume-title":"Metagonimus hakubaensis<\/italic> sp. n. 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