{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T16:28:17Z","timestamp":1793896097386,"version":"4.8.0"},"reference-count":29,"publisher":"Yonsei University College of Medicine","issue":"6","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0"}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["Yonsei Med J"],"published-print":{"date-parts":[[2010]]},"DOI":"10.3349\/ymj.2010.51.6.912","type":"journal-article","created":{"date-parts":[[2010,10,7]],"date-time":"2010-10-07T04:50:56Z","timestamp":1286427056000},"page":"912","update-policy":"https:\/\/doi.org\/10.3349\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Association between Cystic Fibrosis Transmembrane Conductance Regulator Gene Mutations and Susceptibility for Childhood Asthma in Korea"],"prefix":"10.3349","volume":"51","author":[{"given":"Kyung Won","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Pediatrics and Institute of Allergy, Brain Korea 21 Project for Medical Science, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Hyun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Brain Korea 21 Project for Medical Science, Pharmacogenomic Research Center for Drug Transporters, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Goo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Brain Korea 21 Project for Medical Science, Pharmacogenomic Research Center for Drug Transporters, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung Hwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Brain Korea 21 Project for Medical Science, Pharmacogenomic Research Center for Drug Transporters, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myung Hyun","family":"Sohn","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Institute of Allergy, Brain Korea 21 Project for Medical Science, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyu-Earn","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Institute of Allergy, Brain Korea 21 Project for Medical Science, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1901","reference":[{"issue":"Suppl 61","key":"10.3349\/ymj.2010.51.6.912_ref1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1034\/j.1398-9995.2000.00513.x","volume":"55","author":"Maselli","year":"2000","journal-title":"Allergy"},{"key":"10.3349\/ymj.2010.51.6.912_ref2","doi-asserted-by":"crossref","first-page":"629","DOI":"10.3349\/ymj.2005.46.5.629","volume":"46","author":"Shin","year":"2005","journal-title":"Yonsei Med J"},{"key":"10.3349\/ymj.2010.51.6.912_ref3","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1146\/annurev.med.53.082901.103921","volume":"53","author":"Maddox","year":"2002","journal-title":"Annu Rev Med"},{"key":"10.3349\/ymj.2010.51.6.912_ref4","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/rr179","volume":"3","author":"Sengler","year":"2002","journal-title":"Respir Res"},{"key":"10.3349\/ymj.2010.51.6.912_ref5","doi-asserted-by":"crossref","first-page":"569","DOI":"10.3349\/ymj.2009.50.4.569","volume":"50","author":"Nam","year":"2009","journal-title":"Yonsei Med J"},{"key":"10.3349\/ymj.2010.51.6.912_ref6","doi-asserted-by":"crossref","first-page":"182","DOI":"10.3349\/ymj.2009.50.2.182","volume":"50","author":"Kim","year":"2009","journal-title":"Yonsei Med J"},{"key":"10.3349\/ymj.2010.51.6.912_ref7","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1016\/j.rmed.2006.03.026","volume":"100","author":"Munthe-Kaas","year":"2006","journal-title":"Respir Med"},{"key":"10.3349\/ymj.2010.51.6.912_ref8","doi-asserted-by":"crossref","first-page":"157","DOI":"10.3346\/jkms.1988.3.4.157","volume":"3","author":"Moon","year":"1988","journal-title":"J Korean Med Sci"},{"key":"10.3349\/ymj.2010.51.6.912_ref9","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3346\/jkms.2005.20.1.153","volume":"20","author":"Ahn","year":"2005","journal-title":"J Korean Med Sci"},{"key":"10.3349\/ymj.2010.51.6.912_ref10","doi-asserted-by":"crossref","first-page":"563","DOI":"10.3346\/jkms.2006.21.3.563","volume":"21","author":"Koh","year":"2006","journal-title":"J Korean Med Sci"},{"key":"10.3349\/ymj.2010.51.6.912_ref11","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1093\/hmg\/ddg243","volume":"12","author":"Lee","year":"2003","journal-title":"Hum Mol Genet"},{"key":"10.3349\/ymj.2010.51.6.912_ref12","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1007\/s10620-005-2950-9","volume":"50","author":"Lee","year":"2005","journal-title":"Dig Dis Sci"},{"key":"10.3349\/ymj.2010.51.6.912_ref13","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1164\/ajrccm.161.1.ats11-99","volume":"161","author":"Crapo","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"10.3349\/ymj.2010.51.6.912_ref14","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.jaci.2004.05.023","volume":"114","author":"Sedgwick","year":"2004","journal-title":"J Allergy Clin Immunol"},{"key":"10.3349\/ymj.2010.51.6.912_ref15","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1097\/00008571-200208000-00004","volume":"12","author":"Tang","year":"2002","journal-title":"Pharmacogenetics"},{"key":"10.3349\/ymj.2010.51.6.912_ref16","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1086\/338446","volume":"70","author":"Niu","year":"2002","journal-title":"Am J Hum Genet"},{"key":"10.3349\/ymj.2010.51.6.912_ref17","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1038\/nm1095-978b","volume":"1","author":"Mennie","year":"1995","journal-title":"Nat Med"},{"key":"10.3349\/ymj.2010.51.6.912_ref18","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/sj.ejhg.5200578","volume":"9","author":"de Cid","year":"2001","journal-title":"Eur J Hum Genet"},{"key":"10.3349\/ymj.2010.51.6.912_ref19","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1089\/10906570152742317","volume":"5","author":"Castellani","year":"2001","journal-title":"Genet Test"},{"key":"10.3349\/ymj.2010.51.6.912_ref20","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.jcf.2006.02.002","volume":"5","author":"Ngiam","year":"2006","journal-title":"J Cyst Fibros"},{"key":"10.3349\/ymj.2010.51.6.912_ref21","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.1164\/ajrccm.164.11.2101086","volume":"164","author":"Hakonarson","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.3349\/ymj.2010.51.6.912_ref22","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1016\/S0140-6736(97)11419-2","volume":"351","author":"Dahl","year":"1998","journal-title":"Lancet"},{"key":"10.3349\/ymj.2010.51.6.912_ref23","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1007\/s004390100467","volume":"108","author":"Tzetis","year":"2001","journal-title":"Hum Genet"},{"key":"10.3349\/ymj.2010.51.6.912_ref24","first-page":"345","volume":"1","author":"Douros","year":"2008","journal-title":"Int J Clin Exp Med"},{"key":"10.3349\/ymj.2010.51.6.912_ref25","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1002\/(SICI)1098-1004(199912)14:6<510::AID-HUMU10>3.0.CO;2-O","volume":"14","author":"L\u00e1zaro","year":"1999","journal-title":"Hum Mutat"},{"key":"10.3349\/ymj.2010.51.6.912_ref26","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/nm0795-703","volume":"1","author":"Schroeder","year":"1995","journal-title":"Nat Med"},{"key":"10.3349\/ymj.2010.51.6.912_ref27","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1093\/hmg\/3.4.607","volume":"3","author":"Cuppens","year":"1994","journal-title":"Hum Mol Genet"},{"key":"10.3349\/ymj.2010.51.6.912_ref28","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1067\/mai.2001.114117","volume":"107","author":"Dahl","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"10.3349\/ymj.2010.51.6.912_ref29","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1164\/ajrccm\/138.2.312","volume":"138","author":"Byard","year":"1988","journal-title":"Am Rev Respir Dis"}],"container-title":["Yonsei Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3349\/ymj.2010.51.6.912","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.3349\/ymj.2010.51.6.912","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eymj.org\/DOIx.php?id=10.3349\/ymj.2010.51.6.912","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T07:32:15Z","timestamp":1589527935000},"score":1,"resource":{"primary":{"URL":"https:\/\/eymj.org\/DOIx.php?id=10.3349\/ymj.2010.51.6.912"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.3349\/ymj.2010.51.6.912","relation":{},"ISSN":["0513-5796"],"issn-type":[{"value":"0513-5796","type":"print"}],"subject":[],"published":{"date-parts":[[2010]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3349\/ymj.2010.51.6.912","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3349\/ymj.2010.51.6.912","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"http:\/\/www.eymj.org\/DOIx.php?id=10.3349\/ymj.2010.51.6.912","URL":"http:\/\/www.eymj.org\/DOIx.php?id=10.3349\/ymj.2010.51.6.912","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2009-11-05","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-01-12","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-01-18","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-09-30","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 Copyright: Yonsei University College of Medicine 2010","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}