{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T16:23:05Z","timestamp":1782922985983,"version":"3.54.5"},"reference-count":44,"publisher":"Yonsei University College of Medicine","issue":"4","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0"}],"funder":[{"name":"Scientific Research Fund of the Chinese Ministry of Education","award":["30960128"],"award-info":[{"award-number":["30960128"]}]},{"name":"Scientific Research Fund of the Chinese Ministry of Education","award":["82160068"],"award-info":[{"award-number":["82160068"]}]},{"name":"Ministry of Education, Science and Technology of Korea","award":["2010-0019913"],"award-info":[{"award-number":["2010-0019913"]}]}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["Yonsei Med J"],"published-print":{"date-parts":[[2014]]},"DOI":"10.3349\/ymj.2014.55.4.912","type":"journal-article","created":{"date-parts":[[2014,6,20]],"date-time":"2014-06-20T10:00:56Z","timestamp":1403258456000},"page":"912","update-policy":"https:\/\/doi.org\/10.3349\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Increased Serum Cathepsin K in Patients with Coronary Artery Disease"],"prefix":"10.3349","volume":"55","author":[{"given":"Xiang","family":"Li","sequence":"first","affiliation":[{"name":"Department of Cardiology, Yanbian University Hospital, Yanji, Jilin P.R., China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuzi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yanbian University Hospital, Yanji, Jilin P.R., China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiyong","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yanbian University Hospital, Yanji, Jilin P.R., China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dehao","family":"Jin","sequence":"additional","affiliation":[{"name":"Intervention Laboratory, Yanbian University Hospital, Yanji, Jilin P.R., China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yanbian University Hospital, Yanji, Jilin P.R., China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangshan","family":"Li","sequence":"additional","affiliation":[{"name":"Central Laboratory, Yanbian University Hospital, Yanji, Jilin P.R., China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanna","family":"Rei","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yanbian University Hospital, Yanji, Jilin P.R., China."},{"name":"Department of Anesthesiology, Yanbian University Hospital, Yanji, Jilin P.R., China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiying","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pathophysiology, Yanbian University Medical College, Yanji, Jilin P.R., China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangxian","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yanbian University Hospital, Yanji, Jilin P.R., China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yanbian University Hospital, Yanji, Jilin P.R., China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enbo","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yanbian University Hospital, Yanji, Jilin P.R., China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongshan","family":"Nan","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Yanbian University Hospital, Yanji, Jilin P.R., China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianwu","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yanbian University Hospital, Yanji, Jilin P.R., China."},{"name":"Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan."},{"name":"Department of Internal Medicine, Kyung Hee University Hospital, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1901","reference":[{"key":"10.3349\/ymj.2014.55.4.912_ref1","doi-asserted-by":"crossref","first-page":"4629","DOI":"10.1093\/emboj\/20.17.4629","volume":"20","author":"Turk","year":"2001","journal-title":"EMBO J"},{"key":"10.3349\/ymj.2014.55.4.912_ref2","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1161\/CIRCULATIONAHA.111.066712","volume":"125","author":"Cheng","year":"2012","journal-title":"Circulation"},{"key":"10.3349\/ymj.2014.55.4.912_ref3","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1161\/HYPERTENSIONAHA.111.180935","volume":"58","author":"Cheng","year":"2011","journal-title":"Hypertension"},{"key":"10.3349\/ymj.2014.55.4.912_ref4","doi-asserted-by":"crossref","first-page":"3421","DOI":"10.1172\/JCI42918","volume":"120","author":"Reiser","year":"2010","journal-title":"J Clin Invest"},{"key":"10.3349\/ymj.2014.55.4.912_ref5","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1172\/JCI181","volume":"102","author":"Sukhova","year":"1998","journal-title":"J Clin Invest"},{"key":"10.3349\/ymj.2014.55.4.912_ref6","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1172\/JCI7709","volume":"104","author":"Shi","year":"1999","journal-title":"J Clin Invest"},{"key":"10.3349\/ymj.2014.55.4.912_ref7","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0002-9440(10)63114-8","volume":"164","author":"Cheng","year":"2004","journal-title":"Am J Pathol"},{"key":"10.3349\/ymj.2014.55.4.912_ref8","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.cardiores.2004.02.002","volume":"62","author":"Burns-Kurtis","year":"2004","journal-title":"Cardiovasc Res"},{"key":"10.3349\/ymj.2014.55.4.912_ref9","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1093\/cvr\/cvq328","volume":"89","author":"Sun","year":"2011","journal-title":"Cardiovasc Res"},{"key":"10.3349\/ymj.2014.55.4.912_ref10","doi-asserted-by":"crossref","first-page":"2500","DOI":"10.1161\/ATVBAHA.111.230201","volume":"31","author":"Sun","year":"2011","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.3349\/ymj.2014.55.4.912_ref11","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1161\/ATVBAHA.111.235002","volume":"32","author":"Sun","year":"2012","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.3349\/ymj.2014.55.4.912_ref12","doi-asserted-by":"crossref","first-page":"358","DOI":"10.2353\/ajpath.2008.071126","volume":"173","author":"Cheng","year":"2008","journal-title":"Am J Pathol"},{"key":"10.3349\/ymj.2014.55.4.912_ref13","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1021\/bi992251u","volume":"39","author":"Li","year":"2000","journal-title":"Biochemistry"},{"key":"10.3349\/ymj.2014.55.4.912_ref14","doi-asserted-by":"crossref","first-page":"7893","DOI":"10.1074\/jbc.M610107200","volume":"282","author":"Novinec","year":"2007","journal-title":"J Biol Chem"},{"key":"10.3349\/ymj.2014.55.4.912_ref15","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.atherosclerosis.2005.05.012","volume":"184","author":"Liu","year":"2006","journal-title":"Atherosclerosis"},{"key":"10.3349\/ymj.2014.55.4.912_ref16","doi-asserted-by":"crossref","first-page":"685","DOI":"10.2353\/ajpath.2006.050295","volume":"168","author":"Cheng","year":"2006","journal-title":"Am J Pathol"},{"key":"10.3349\/ymj.2014.55.4.912_ref17","doi-asserted-by":"crossref","first-page":"3029","DOI":"10.1096\/fj.06-7924com","volume":"21","author":"Lutgens","year":"2007","journal-title":"FASEB J"},{"key":"10.3349\/ymj.2014.55.4.912_ref18","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1161\/CIRCULATIONAHA.105.561449","volume":"113","author":"Lutgens","year":"2006","journal-title":"Circulation"},{"key":"10.3349\/ymj.2014.55.4.912_ref19","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1161\/HYPERTENSIONAHA.111.00947","volume":"61","author":"Hua","year":"2013","journal-title":"Hypertension"},{"key":"10.3349\/ymj.2014.55.4.912_ref20","doi-asserted-by":"crossref","first-page":"498","DOI":"10.2337\/db12-0350","volume":"62","author":"Hua","year":"2013","journal-title":"Diabetes"},{"key":"10.3349\/ymj.2014.55.4.912_ref21","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1161\/01.HYP.0000242331.99369.2f","volume":"48","author":"Cheng","year":"2006","journal-title":"Hypertension"},{"key":"10.3349\/ymj.2014.55.4.912_ref22","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1161\/HYPERTENSIONAHA.111.187807","volume":"59","author":"Smith","year":"2012","journal-title":"Hypertension"},{"key":"10.3349\/ymj.2014.55.4.912_ref23","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.atherosclerosis.2005.08.001","volume":"186","author":"Liu","year":"2006","journal-title":"Atherosclerosis"},{"key":"10.3349\/ymj.2014.55.4.912_ref24","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1093\/eurheartj\/ehs184","volume":"33","author":"Thygesen","year":"2012","journal-title":"Eur Heart J"},{"key":"10.3349\/ymj.2014.55.4.912_ref25","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1016\/S0735-1097(01)01175-5","volume":"37","author":"Mintz","year":"2001","journal-title":"J Am Coll Cardiol"},{"key":"10.3349\/ymj.2014.55.4.912_ref26","first-page":"883","volume":"369","author":"Libby","year":"2013","journal-title":"N Engl J Med"},{"key":"10.3349\/ymj.2014.55.4.912_ref27","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/j.immuni.2013.06.009","volume":"38","author":"Libby","year":"2013","journal-title":"Immunity"},{"key":"10.3349\/ymj.2014.55.4.912_ref28","doi-asserted-by":"crossref","first-page":"77","DOI":"10.4068\/cmj.2012.48.2.77","volume":"48","author":"Li","year":"2012","journal-title":"Chonnam Med J"},{"key":"10.3349\/ymj.2014.55.4.912_ref29","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.ijcard.2010.08.061","volume":"145","author":"Zografos","year":"2010","journal-title":"Int J Cardiol"},{"key":"10.3349\/ymj.2014.55.4.912_ref30","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.amjcard.2008.10.011","volume":"103","author":"Liu","year":"2009","journal-title":"Am J Cardiol"},{"key":"10.3349\/ymj.2014.55.4.912_ref31","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1161\/CIRCULATIONAHA.110.970038","volume":"123","author":"Chatzizisis","year":"2011","journal-title":"Circulation"},{"key":"10.3349\/ymj.2014.55.4.912_ref32","doi-asserted-by":"crossref","first-page":"H1479","DOI":"10.1152\/ajpheart.00954.2006","volume":"292","author":"Platt","year":"2007","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.3349\/ymj.2014.55.4.912_ref33","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1056\/NEJMra1216063","volume":"368","author":"Libby","year":"2013","journal-title":"N Engl J Med"},{"key":"10.3349\/ymj.2014.55.4.912_ref34","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.atherosclerosis.2009.02.014","volume":"206","author":"Nakamura","year":"2009","journal-title":"Atherosclerosis"},{"key":"10.3349\/ymj.2014.55.4.912_ref35","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.atherosclerosis.2010.05.013","volume":"213","author":"Hermus","year":"2010","journal-title":"Atherosclerosis"},{"key":"10.3349\/ymj.2014.55.4.912_ref36","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.atherosclerosis.2006.11.013","volume":"196","author":"Geluk","year":"2008","journal-title":"Atherosclerosis"},{"key":"10.3349\/ymj.2014.55.4.912_ref37","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1161\/CIRCULATIONAHA.105.596031","volume":"113","author":"Liang","year":"2006","journal-title":"Circulation"},{"key":"10.3349\/ymj.2014.55.4.912_ref38","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1161\/hc0902.104353","volume":"105","author":"Libby","year":"2002","journal-title":"Circulation"},{"key":"10.3349\/ymj.2014.55.4.912_ref39","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1172\/JCI200314915","volume":"111","author":"Sukhova","year":"2003","journal-title":"J Clin Invest"},{"key":"10.3349\/ymj.2014.55.4.912_ref40","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.atherosclerosis.2009.12.031","volume":"210","author":"Sasaki","year":"2010","journal-title":"Atherosclerosis"},{"key":"10.3349\/ymj.2014.55.4.912_ref41","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1161\/01.ATV.0000261709.34878.20","volume":"27","author":"Schwartz","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.3349\/ymj.2014.55.4.912_ref42","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.amjcard.2005.08.020","volume":"97","author":"Fukuda","year":"2006","journal-title":"Am J Cardiol"},{"key":"10.3349\/ymj.2014.55.4.912_ref43","doi-asserted-by":"crossref","first-page":"34776","DOI":"10.1074\/jbc.M310814200","volume":"279","author":"O\u00f6rni","year":"2004","journal-title":"J Biol Chem"},{"key":"10.3349\/ymj.2014.55.4.912_ref44","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.bbrc.2003.11.020","volume":"312","author":"Lindstedt","year":"2003","journal-title":"Biochem Biophys Res Commun"}],"container-title":["Yonsei Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3349\/ymj.2014.55.4.912","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.3349\/ymj.2014.55.4.912","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eymj.org\/DOIx.php?id=10.3349\/ymj.2014.55.4.912","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T07:41:45Z","timestamp":1589528505000},"score":1,"resource":{"primary":{"URL":"https:\/\/eymj.org\/DOIx.php?id=10.3349\/ymj.2014.55.4.912"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.3349\/ymj.2014.55.4.912","relation":{},"ISSN":["0513-5796","1976-2437"],"issn-type":[{"value":"0513-5796","type":"print"},{"value":"1976-2437","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3349\/ymj.2014.55.4.912","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.3349\/ymj.2014.55.4.912","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"http:\/\/www.eymj.org\/DOIx.php?id=10.3349\/ymj.2014.55.4.912","URL":"http:\/\/www.eymj.org\/DOIx.php?id=10.3349\/ymj.2014.55.4.912","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2013-09-13","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-10-05","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-10-11","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-06-13","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 Copyright: Yonsei University College of Medicine 2014","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}