{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T10:33:56Z","timestamp":1747218836374,"version":"3.40.5"},"reference-count":40,"publisher":"XMLink","issue":"12","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002569","name":"Wonkwang University","doi-asserted-by":"publisher","award":["2020-03-20-68"],"award-info":[{"award-number":["2020-03-20-68"]}],"id":[{"id":"10.13039\/501100002569","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["eymj.org"],"crossmark-restriction":false},"short-container-title":["Yonsei Med J"],"published-print":{"date-parts":[[2020]]},"DOI":"10.3349\/ymj.2020.61.12.1042","type":"journal-article","created":{"date-parts":[[2020,11,27]],"date-time":"2020-11-27T05:26:36Z","timestamp":1606454796000},"page":"1042","update-policy":"https:\/\/doi.org\/10.3349\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Combination Therapy by Tissue-Specific Suicide Gene and Bevacizumab in Intramedullary Spinal Cord Tumor"],"prefix":"10.3349","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4642-5226","authenticated-orcid":false,"given":"So-Jung","family":"Gwak","sequence":"first","affiliation":[{"name":"Department of Chemical Engineering, Wonkwang University, Iksan, Korea."},{"name":"Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8925-0468","authenticated-orcid":false,"given":"Lihua","family":"Che","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea."},{"name":"Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0927-107X","authenticated-orcid":false,"given":"Yeomin","family":"Yun","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea."},{"name":"Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7083-9296","authenticated-orcid":false,"given":"Minhyung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Bioengineering, College of Engineering, Hanyang University, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3775-2324","authenticated-orcid":false,"given":"Yoon","family":"Ha","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea."},{"name":"Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18617","reference":[{"key":"10.3349\/ymj.2020.61.12.1042_ref1","doi-asserted-by":"crossref","first-page":"S617","DOI":"10.4103\/2152-7806.189733","volume":"7","author":"Bakhshi","year":"2016","journal-title":"Surg Neurol Int"},{"key":"10.3349\/ymj.2020.61.12.1042_ref2","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1055\/s-0035-1549029","volume":"5","author":"Samartzis","year":"2015","journal-title":"Global Spine J"},{"volume-title":"Glioblastoma [Internet]","year":"2017","author":"Fernandes","key":"10.3349\/ymj.2020.61.12.1042_ref3"},{"key":"10.3349\/ymj.2020.61.12.1042_ref4","doi-asserted-by":"crossref","first-page":"E65","DOI":"10.1097\/BRS.0000000000000070","volume":"39","author":"Gwak","year":"2014","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3349\/ymj.2020.61.12.1042_ref5","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s13018-018-0735-z","volume":"13","author":"Uei","year":"2018","journal-title":"J Orthop Surg Res"},{"key":"10.3349\/ymj.2020.61.12.1042_ref6","doi-asserted-by":"crossref","first-page":"e27670","DOI":"10.1002\/pbc.27670","volume":"66 Suppl 3","author":"Pio","year":"2019","journal-title":"Pediatr Blood Cancer"},{"key":"10.3349\/ymj.2020.61.12.1042_ref7","first-page":"397","volume":"24","author":"Alexiou","year":"2019","journal-title":"J BUON"},{"key":"10.3349\/ymj.2020.61.12.1042_ref8","doi-asserted-by":"crossref","first-page":"3223","DOI":"10.7150\/thno.40298","volume":"10","author":"Yang","year":"2020","journal-title":"Theranostics"},{"key":"10.3349\/ymj.2020.61.12.1042_ref9","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s11060-016-2091-3","volume":"128","author":"Lee","year":"2016","journal-title":"J Neurooncol"},{"key":"10.3349\/ymj.2020.61.12.1042_ref10","first-page":"5565","volume":"60","author":"Lee","year":"2000","journal-title":"Cancer Res"},{"key":"10.3349\/ymj.2020.61.12.1042_ref11","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.bbrc.2005.05.132","volume":"333","author":"Ferrara","year":"2005","journal-title":"Biochem Biophys Res Commun"},{"key":"10.3349\/ymj.2020.61.12.1042_ref12","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1158\/0008-5472.CAN-11-3831","volume":"72","author":"Hu","year":"2012","journal-title":"Cancer Res"},{"key":"10.3349\/ymj.2020.61.12.1042_ref13","doi-asserted-by":"crossref","first-page":"429","DOI":"10.2147\/OTT.S125587","volume":"10","author":"Hata","year":"2017","journal-title":"Onco Targets Ther"},{"key":"10.3349\/ymj.2020.61.12.1042_ref14","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jconrel.2016.01.047","volume":"226","author":"Lee","year":"2016","journal-title":"J Control Release"},{"key":"10.3349\/ymj.2020.61.12.1042_ref15","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1021\/mp4006003","volume":"11","author":"Kim","year":"2014","journal-title":"Mol Pharm"},{"key":"10.3349\/ymj.2020.61.12.1042_ref16","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1002\/jps.24363","volume":"104","author":"Oh","year":"2015","journal-title":"J Pharm Sci"},{"key":"10.3349\/ymj.2020.61.12.1042_ref17","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1002\/jgm.1110","volume":"9","author":"Horst","year":"2007","journal-title":"J Gene Med"},{"key":"10.3349\/ymj.2020.61.12.1042_ref18","first-page":"205","volume":"434","author":"Zheng","year":"2008","journal-title":"Methods Mol Biol"},{"key":"10.3349\/ymj.2020.61.12.1042_ref19","doi-asserted-by":"crossref","first-page":"6113","DOI":"10.1158\/1078-0432.CCR-09-1087","volume":"15","author":"Ghulam Muhammad","year":"2009","journal-title":"Clin Cancer Res"},{"key":"10.3349\/ymj.2020.61.12.1042_ref20","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3389\/fonc.2019.00043","volume":"9","author":"Campillo","year":"2019","journal-title":"Front Oncol"},{"key":"10.3349\/ymj.2020.61.12.1042_ref21","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1023\/A:1015832726054","volume":"58","author":"Beppu","year":"2002","journal-title":"J Neurooncol"},{"key":"10.3349\/ymj.2020.61.12.1042_ref22","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/nrc704","volume":"2","author":"Harris","year":"2002","journal-title":"Nat Rev Cancer"},{"key":"10.3349\/ymj.2020.61.12.1042_ref23","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/0092-8674(90)90662-X","volume":"60","author":"Lendahl","year":"1990","journal-title":"Cell"},{"key":"10.3349\/ymj.2020.61.12.1042_ref24","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1111\/j.1460-9568.1997.tb01622.x","volume":"9","author":"Lothian","year":"1997","journal-title":"Eur J Neurosci"},{"key":"10.3349\/ymj.2020.61.12.1042_ref25","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0896-6273(94)90148-1","volume":"12","author":"Zimmerman","year":"1994","journal-title":"Neuron"},{"key":"10.3349\/ymj.2020.61.12.1042_ref26","doi-asserted-by":"crossref","first-page":"e0147389","DOI":"10.1371\/journal.pone.0147389","volume":"11","author":"Gwak","year":"2016","journal-title":"PLoS One"},{"key":"10.3349\/ymj.2020.61.12.1042_ref27","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1590\/S1807-59322008000100018","volume":"63","author":"Barros Filho","year":"2008","journal-title":"Clinics (Sao Paulo)"},{"key":"10.3349\/ymj.2020.61.12.1042_ref28","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s11940-009-0035-3","volume":"11","author":"Vaillant","year":"2009","journal-title":"Curr Treat Options Neurol"},{"key":"10.3349\/ymj.2020.61.12.1042_ref29","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.wneu.2018.11.113","volume":"122","author":"Chanchotisatien","year":"2019","journal-title":"World Neurosurg"},{"key":"10.3349\/ymj.2020.61.12.1042_ref30","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.ejpn.2014.09.007","volume":"19","author":"Kutluk","year":"2015","journal-title":"Eur J Paediatr Neurol"},{"key":"10.3349\/ymj.2020.61.12.1042_ref31","doi-asserted-by":"crossref","first-page":"573","DOI":"10.3390\/nano9040573","volume":"9","author":"Gwak","year":"2019","journal-title":"Nanomaterials (Basel)"},{"key":"10.3349\/ymj.2020.61.12.1042_ref32","first-page":"3871","volume":"37","author":"Okuda","year":"2017","journal-title":"Anticancer Res"},{"key":"10.3349\/ymj.2020.61.12.1042_ref33","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s11060-006-9279-x","volume":"82","author":"Huang","year":"2007","journal-title":"J Neurooncol"},{"key":"10.3349\/ymj.2020.61.12.1042_ref34","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1002\/jnr.10376","volume":"69","author":"Johansson","year":"2002","journal-title":"J Neurosci Res"},{"key":"10.3349\/ymj.2020.61.12.1042_ref35","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.celrep.2017.10.001","volume":"21","author":"Sonawane","year":"2017","journal-title":"Cell Rep"},{"key":"10.3349\/ymj.2020.61.12.1042_ref36","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.nec.2013.12.010","volume":"25","author":"Tredway","year":"2014","journal-title":"Neurosurg Clin N Am"},{"key":"10.3349\/ymj.2020.61.12.1042_ref37","doi-asserted-by":"crossref","first-page":"3670","DOI":"10.1158\/1535-7163.MCT-08-0715","volume":"7","author":"Ma","year":"2008","journal-title":"Mol Cancer Ther"},{"key":"10.3349\/ymj.2020.61.12.1042_ref38","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3389\/fcell.2017.00101","volume":"5","author":"Comunanza","year":"2017","journal-title":"Front Cell Dev Biol"},{"key":"10.3349\/ymj.2020.61.12.1042_ref39","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1200\/JCO.2012.46.2762","volume":"31","author":"Lambrechts","year":"2013","journal-title":"J Clin Oncol"},{"key":"10.3349\/ymj.2020.61.12.1042_ref40","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.pdpdt.2018.06.008","volume":"23","author":"Peng","year":"2018","journal-title":"Photodiagnosis Photodyn Ther"}],"container-title":["Yonsei Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/eymj.org\/pdf\/10.3349\/ymj.2020.61.12.1042","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eymj.org\/DOIx.php?id=10.3349\/ymj.2020.61.12.1042","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eymj.org\/DOIx.php?id=10.3349\/ymj.2020.61.12.1042","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T02:43:15Z","timestamp":1697251395000},"score":1,"resource":{"primary":{"URL":"https:\/\/eymj.org\/DOIx.php?id=10.3349\/ymj.2020.61.12.1042"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":40,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.3349\/ymj.2020.61.12.1042","relation":{},"ISSN":["0513-5796","1976-2437"],"issn-type":[{"type":"print","value":"0513-5796"},{"type":"electronic","value":"1976-2437"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"2020-06-18","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-11","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-19","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-25","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 Copyright: Yonsei University College of Medicine 2020","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}