{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T22:52:45Z","timestamp":1790981565475,"version":"4.1.0"},"reference-count":29,"publisher":"The Korean Association for the Study of the Liver","issue":"Suppl","license":[{"start":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T00:00:00Z","timestamp":1674604800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["e-cmh.org"],"crossmark-restriction":true},"short-container-title":["Clin Mol Hepatol"],"published-print":{"date-parts":[[2023,2,28]]},"abstract":"<jats:p>Nonalcoholic fatty liver disease (NAFLD) affects approximately 30% of the population worldwide and includes nonalcoholic fatty liver, nonalcoholic steatohepatitis (NASH), and cirrhosis. Since NAFLD-associated diseases begin with steatosis, the early diagnosis of steatosis helps to prevent the progression of NASH and fibrosis. In addition, more convenient and easily diagnosable serum biomarkers are becoming crucial in disease diagnosis. In this report, we summarize the known serum biomarkers for liver steatosis and provide guidance for their application in clinical practice.<\/jats:p>","DOI":"10.3350\/cmh.2022.0362","type":"journal-article","created":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T19:44:48Z","timestamp":1674675888000},"page":"S150-S156","update-policy":"https:\/\/doi.org\/10.3350\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Noninvasive serum biomarkers for liver steatosis in nonalcoholic fatty liver disease: Current and future developments"],"prefix":"10.3350","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7419-5259","authenticated-orcid":true,"given":"Sang Bong","family":"Ahn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1902","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29367"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2018.0037"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2021.0178"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000002020"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01526.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2022.0099"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2022.0239"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159\/000469304"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20818"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20466"},{"key":"ref11","first-page":"41","volume-title":"Mildly elevated liver transaminase levels in the asymptomatic patient. Am Fam Physician 2005;71:1105-1110","author":"Giboney","year":"2005"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2003.50193"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2004.07.010"},{"key":"ref14","first-page":"1433","volume-title":"Serum gamma-glutamyltranspeptidase distinguishes non-alcoholic fatty liver disease at high risk","author":"Tahan","year":"2008"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1186\/1476-5926-4-10"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0030325"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230x-6-33"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24356"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2009.08.002"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.06.005"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14172"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.21037\/atm-20-2951"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2017.09.020"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2017.01.021"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230x-10-98"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1530\/eje-14-0112"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.12665"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9092851"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2021.0127"}],"container-title":["Clinical and Molecular Hepatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/e-cmh.org\/upload\/pdf\/cmh-2022-0362.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-cmh.org\/journal\/view.php?doi=10.3350\/cmh.2022.0362","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-cmh.org\/upload\/pdf\/cmh-2022-0362.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T00:11:49Z","timestamp":1678752709000},"score":1,"resource":{"primary":{"URL":"http:\/\/e-cmh.org\/journal\/view.php?doi=10.3350\/cmh.2022.0362"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,28]]},"references-count":29,"journal-issue":{"issue":"Suppl","published-print":{"date-parts":[[2023,2]]}},"URL":"https:\/\/doi.org\/10.3350\/cmh.2022.0362","relation":{},"ISSN":["2287-2728","2287-285X"],"issn-type":[{"value":"2287-2728","type":"print"},{"value":"2287-285X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,28]]},"assertion":[{"value":"2022-11-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-25","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-28","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}